{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T20:10:36Z","timestamp":1779912636400,"version":"3.53.1"},"reference-count":16,"publisher":"Termedia Sp. z.o.o.","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anaesthesiol Intensive Ther"],"abstract":"Introduction<\/jats:title>Malnutrition in surgical patients remains a common issue affecting the perioperative period. Oesophageal cancer is a disease associated with one of the highest malnutrition rates. Assessment of patient nutritional status remains a challenge due to limited validated tools. Novel parameters to identify malnourished patients and the effectiveness of preoperative nutritional intervention might improve treatment results in the perioperative period.<\/jats:p><\/jats:sec>Material and methods<\/jats:title>This was a prospective, observational, single-centre study of patients scheduled for elective oesophagectomy. The primary aim of this study was to establish the correlation between neutrophil reactivity intensity (NEUT-RI) and neutrophil granularity intensity (NEUT-GI) and patients\u2019 nutritional status. We divided patients into nutritional responders (R group) and nutritional non-responders (NR group) defined as regaining at least 25% of the maximum preoperative body weight loss during the preoperative period.<\/jats:p><\/jats:sec>Results<\/jats:title>The R group had significantly shorter intensive care unit (ICU) stays: 5.5 (4\u20138) vs. 13 (7\u201331) days (<i>P<\/i> = 0.01). It resulted in a lower cost of ICU stays in the R group: 4775.2 (3938.9\u20137640.7) vs. 12255.8 (7787.6\u201349108.7) euro in the NR group (<i>P<\/i> = 0.01). Between the R group and the NR group, we observed statistically significant differences in both preoperative NEUT-RI (48.6 vs. 53.4, <i>P<\/i> = 0.03) and NEUT-GI (154.6 vs. 159.3, <i>P<\/i> = 0.02). Apart from the T grade, the only preoperative factor associated with reduced mortality was the nutritional responsiveness: 11.1% vs. 71.4% (<i>P<\/i> = 0.008).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Preoperative nutritional responsiveness affects neutrophil intensity indexes and reduces in-hospital mortality and costs associated with hospital stay. Further research is required to determine the correlation between novel neutrophil parameters and patients\u2019 nutritional status.<\/jats:p><\/jats:sec>","DOI":"10.5114\/ait.2024.136013","type":"journal-article","created":{"date-parts":[[2024,3,7]],"date-time":"2024-03-07T11:51:45Z","timestamp":1709812305000},"page":"77-82","source":"Crossref","is-referenced-by-count":2,"title":["Nutritional responsiveness affects novel neutrophil parameters and reduces in-hospital mortality and costs in elective cancer oesophagectomy \u2013 a single centre, prospective, observational study"],"prefix":"10.5114","volume":"56","author":[{"given":"Pawe\u0142","family":"Kutnik","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Micha\u0142","family":"Borys","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamil","family":"Nurczyk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weronika","family":"Domerecka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacek","family":"Dziedzic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grzegorz","family":"Buszewicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grzegorz","family":"Teresi\u0144ski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helena","family":"Donica","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pawe\u0142","family":"Piwowarczyk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miros\u0142aw","family":"Czuczwar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3061","published-online":{"date-parts":[[2024,3,7]]},"reference":[{"key":"ref-1373911","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2018.08.002"},{"key":"ref-1373912","doi-asserted-by":"publisher","DOI":"10.5114\/ait.2023.130632"},{"key":"ref-1373913","doi-asserted-by":"publisher","DOI":"10.1016\/j.currproblcancer.2020.100638"},{"key":"ref-1373914","doi-asserted-by":"publisher","DOI":"10.1097\/ACO.0000000000000722"},{"key":"ref-1373915","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-014-2363-4"},{"key":"ref-1373916","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-67202015000300012"},{"key":"ref-1373917","doi-asserted-by":"publisher","DOI":"10.5114\/ait.2023.134190"},{"key":"ref-1373918","doi-asserted-by":"publisher","DOI":"10.3390\/cells11162554"},{"key":"ref-1373919","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000133083.54934.ae"},{"key":"ref-1373920","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2021.03.031"},{"key":"ref-1373921","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19116573"},{"key":"ref-1373922","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7819-3-37"},{"key":"ref-1373923","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2016.09.009"},{"key":"ref-1373924","doi-asserted-by":"publisher","DOI":"10.1007\/s41999-020-00303-4"},{"key":"ref-1373925","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.0663"},{"key":"ref-1373926","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-01-259028"}],"container-title":["Anaesthesiology Intensive Therapy"],"original-title":[],"link":[{"URL":"https:\/\/www.ait-journal.com\/pdf-184227-121684","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ait-journal.com\/pdf-184227-121684","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T10:20:41Z","timestamp":1743070841000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ait-journal.com\/Nutritional-responsiveness-affects-novel-neutrophil-parameters-and-reduces-in-hospital,184227,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,7]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024]]}},"alternative-id":["184227"],"URL":"https:\/\/doi.org\/10.5114\/ait.2024.136013","relation":{},"ISSN":["1642-5758","1731-2531"],"issn-type":[{"value":"1642-5758","type":"print"},{"value":"1731-2531","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,7]]}}}