{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T12:43:57Z","timestamp":1747226637515,"version":"3.40.5"},"reference-count":0,"publisher":"Termedia Sp. z.o.o.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Med Sci"],"published-print":{"date-parts":[[2021,3,10]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Changes typical for cerebral small vessel disease (i.a. white\nmatter hyperintensities \u2013 WMHs) are often found accidentally in neuroimaging studies. Although asymptomatic, this condition increases the risk of future ischaemic incidents and neurodegenerative disorders. Sleep apnoea is\na recognised risk factor for vascular diseases. The aim of our study was to\nassess the prevalence of, and association between, obstructive sleep apnea\n(OSA) and cerebral small vessel disease in the studied population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>Two hundred and seven patients (participants\nof  Prospective Urban Rural Epidemiology Study) took part in our study.\nThe study group consisted of 31 patients with OSA (11 women and 20 men).\nNine of them were diagnosed with mild OSA, nine with moderate OSA, and\n13 with severe OSA. The control group consisted of 176 patients (133 women and 43 men) who scored 0\u20132 points in the  STOP-BANG questionnaire.\nAll patients underwent brain magnetic resonance imaging. We evaluated\nthe occurrence and severity of WMHs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Significantly higher incidence of  WMHs was found in the  study\ngroup compared to controls. In univariate analyses, age was a  significant\npredictor of periventricular white matter changes. For subcortical area, age\nand waist-to-hip ratio were significant predictors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Significantly higher incidence of WMHs in the studied group suggests that patients with OSA may have a higher risk of neurodegeneration.<\/jats:p><\/jats:sec>","DOI":"10.5114\/aoms\/125400","type":"journal-article","created":{"date-parts":[[2021,3,11]],"date-time":"2021-03-11T11:29:44Z","timestamp":1615462184000},"source":"Crossref","is-referenced-by-count":0,"title":["Magnetic resonance white matter changes\nin patients with obstructive sleep apnoea.\nThe subset of the PURE-MIND (Prospective Urban\nand Rural Epidemiological) cohort study"],"prefix":"10.5114","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0615-4927","authenticated-orcid":false,"given":"Katarzyna","family":"Postrzech-Adamczyk","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, 4th Military Hospital, Wroclaw, Poland"},{"name":"Department of Angiology, Hypertension and Diabetology, Wroclaw Medical University,\nWroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Artur","family":"Nahorecki","sequence":"additional","affiliation":[{"name":"Department of Angiology, Hypertension and Diabetology, Wroclaw Medical University,\nWroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jagoda","family":"Jack\u00f3w-Nowicka","sequence":"additional","affiliation":[{"name":"Department of General and Interventional Radiology and Neuroradiology, Wroclaw Medical\nUniversity, Wroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Wo\u0142yniec","sequence":"additional","affiliation":[{"name":"Department of Social Medicine, Wroclaw Medical University, Wroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maciej","family":"Karczewski","sequence":"additional","affiliation":[{"name":"Department of Mathematics, Faculty of Environmental Engineering and Geodesy,\nWroc\u0142aw University of Environmental and Life Sciences, Wroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Skomro","sequence":"additional","affiliation":[{"name":"Department of Angiology, Hypertension and Diabetology, Wroclaw Medical University,\nWroclaw, Poland"},{"name":"University of Saskatchewan, Saskatoon, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Zimny","sequence":"additional","affiliation":[{"name":"Department of General and Interventional Radiology and Neuroradiology, Wroclaw Medical\nUniversity, Wroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrzej","family":"Szuba","sequence":"additional","affiliation":[{"name":"Department of Angiology, Hypertension and Diabetology, Wroclaw Medical University,\nWroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3061","published-online":{"date-parts":[[2021,3,10]]},"container-title":["Archives of Medical Science"],"original-title":[],"link":[{"URL":"https:\/\/www.archivesofmedicalscience.com\/pdf-125400-62528","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.archivesofmedicalscience.com\/pdf-125400-62528","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,29]],"date-time":"2021-10-29T14:17:10Z","timestamp":1635517030000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.archivesofmedicalscience.com\/Magnetic-resonance-white-matter-changes-nin-patients-with-obstructive-sleep-apnoea,125400,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,10]]},"references-count":0,"alternative-id":["125400"],"URL":"https:\/\/doi.org\/10.5114\/aoms\/125400","relation":{},"ISSN":["1734-1922","1896-9151"],"issn-type":[{"type":"print","value":"1734-1922"},{"type":"electronic","value":"1896-9151"}],"subject":[],"published":{"date-parts":[[2021,3,10]]}}}