{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T13:57:55Z","timestamp":1783691875922,"version":"3.55.0"},"reference-count":0,"publisher":"Termedia Sp. z.o.o.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Med Sci"],"published-print":{"date-parts":[[2021,4,10]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Surgical diseases of the thyroid gland in children are rare in\ncomparison with those in the adult population. The aim of the study was to\nassess clinical aspects of thyroid follicular adenoma in children and attempt\nto develop a management algorithm that is useful in clinical practice.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>The clinical database of all children operated on due\nto thyroid disease in the years 1993\u20132018 at the university pediatric surgical center was reviewed. The children in whom the postoperative histology\nreport showed follicular adenoma were selected and their medical files were\nanalyzed in detail. Clinical course of the disease, medical and family history,\nresults of  imaging studies, details of  surgical management and final outcome were assessed in each case.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 183 children operated on for thyroid pathology in the study\nperiod there were 56 patients with follicular adenoma (30.6%). Their age\nranged from 7 to 18 years. Seven patients were found to be hypothyroid\nand a  further seven showed hyperthyroid status initially. Ultrasound scan\nshowed a  solitary nodule in 37 children (66.1%). Multiple nodules in one\nlobe were detected in 5 patients, while a further 14 children showed bilateral thyroid pathology. The result of preoperative cytologic examination was\nsuspicious in 12 children (21.4%). All children were subjected to operative\nmanagement. Forty-two children (75%) underwent at least unilateral total\nlobectomy. No patient showed a recurrent thyroid disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Follicular adenoma in children presents a  wide clinical and\nmorphological spectrum. High incidence of associated diseases of other systems and congenital anomalies of the thyroid gland may indicate a complex\netiology of follicular adenoma with participation of still unknown endogenic\nfactors in children.<\/jats:p><\/jats:sec>","DOI":"10.5114\/aoms\/130994","type":"journal-article","created":{"date-parts":[[2021,4,10]],"date-time":"2021-04-10T17:38:55Z","timestamp":1618076335000},"source":"Crossref","is-referenced-by-count":1,"title":["Follicular adenoma of the thyroid gland in children: a clinical spectrum"],"prefix":"10.5114","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7641-796X","authenticated-orcid":false,"given":"Sylwester","family":"Gerus","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery and Urology, Wroclaw Medical University, Wroclaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcin","family":"Rasiewicz","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery and Urology, Wroclaw Medical University, Wroclaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maciej","family":"Baglaj","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery and Urology, Wroclaw Medical University, Wroclaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3061","published-online":{"date-parts":[[2021,4,10]]},"container-title":["Archives of Medical Science"],"original-title":[],"link":[{"URL":"https:\/\/www.archivesofmedicalscience.com\/pdf-130994-64486","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.archivesofmedicalscience.com\/pdf-130994-64486","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,29]],"date-time":"2021-10-29T14:15:06Z","timestamp":1635516906000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.archivesofmedicalscience.com\/Follicular-adenoma-of-the-thyroid-gland-in-children-a-clinical-spectrum,130994,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,10]]},"references-count":0,"alternative-id":["130994"],"URL":"https:\/\/doi.org\/10.5114\/aoms\/130994","relation":{},"ISSN":["1734-1922","1896-9151"],"issn-type":[{"value":"1734-1922","type":"print"},{"value":"1896-9151","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,10]]}}}