{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,7]],"date-time":"2025-12-07T03:51:10Z","timestamp":1765079470913},"reference-count":0,"publisher":"Termedia Sp. z.o.o.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Med Sci"],"published-print":{"date-parts":[[2021,12,14]]},"abstract":"<jats:p>This meta-analysis was to analyze the clinical presentation, magnetic resonance imaging (MRI) characteristics, and the management of Lymphocytic hypophysitis (LYH).\nMeta-analysis showed that the percentage of women in LYH patients was 78%. LYH was associated with pregnancy in 15% of the female patients, with headache (49%) and symptoms of central diabetes insipidus (CDI) (45%) being the most frequent presentation. In 24 % of the LYH patients, there was an association with another autoimmune disease. The incidence of secondary hypogonadism, secondary hypoadrenalism, secondary hypothyroidism, and growth hormone deficit was 54%, 49%, 43%, and 22%, respectively. Pituitary contrast enhancement (63%), symmetrical pituitary enlargement (60%), thickening of the pituitary stalk (58%), sella mass or suprasellar extension (58%), and loss of posterior pituitary hyperintensity (50%) were typical MRI findings. Regarding LYH treatment, the percentage of patients who had observation or hormone replacement, steroid therapy, and surgery was 43%, 36%, and 34%, respectively.<\/jats:p>","DOI":"10.5114\/aoms\/144628","type":"journal-article","created":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T14:00:51Z","timestamp":1639490451000},"source":"Crossref","is-referenced-by-count":2,"title":["Clinical presentation and magnetic resonance imaging characteristics of lymphocytic hypophysitis: a systematic review with meta-analysis"],"prefix":"10.5114","author":[{"given":"Jia-Sheng","family":"Ju","sequence":"first","affiliation":[{"name":"The Eighth Affiliated Hospital of Sun Yet-sen University, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Cui","sequence":"additional","affiliation":[{"name":"920th Hospital of the Combined Service Force of the Chinese People\u2019s Liberation Army, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Zhao","sequence":"additional","affiliation":[{"name":"920th Hospital of the Combined Service Force of the Chinese People\u2019s Liberation Army, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian-Liang","family":"Chen","sequence":"additional","affiliation":[{"name":"The Eighth Affiliated Hospital of Sun Yet-sen University, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hai-Bing","family":"Ju","sequence":"additional","affiliation":[{"name":"920th Hospital of the Combined Service Force of the Chinese People\u2019s Liberation Army, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3061","published-online":{"date-parts":[[2021,12,14]]},"container-title":["Archives of Medical Science"],"original-title":[],"link":[{"URL":"https:\/\/www.archivesofmedicalscience.com\/pdf-144628-70500","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.archivesofmedicalscience.com\/pdf-144628-70500","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T14:00:53Z","timestamp":1639490453000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.archivesofmedicalscience.com\/Clinical-presentation-and-magnetic-resonance-imaging-characteristics-of-lymphocytic,144628,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,14]]},"references-count":0,"alternative-id":["144628"],"URL":"https:\/\/doi.org\/10.5114\/aoms\/144628","relation":{},"ISSN":["1734-1922","1896-9151"],"issn-type":[{"value":"1734-1922","type":"print"},{"value":"1896-9151","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,14]]}}}