{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T07:48:14Z","timestamp":1768636094970,"version":"3.49.0"},"reference-count":0,"publisher":"Termedia Sp. z.o.o.","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Med Sci"],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>The majority of hepatitis E (HE) reports come from Western Europe. The aim of the study was to describe the typical epidemiological and clinical characteristics of HE in the Czech Republic.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>The retrospective analysis of 173 patients with HE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At least 90% of cases were autochthonous (HEV-3 genotype). Seventeen patients were treated with ribavirin. Five underwent liver transplants because of fulminant HE. We noted neurological symptomatology in 9 cases. Six patients developed chronic HE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There is a possibility of severe health complications caused by the hepatitis E virus in the Czech Republic.<\/jats:p><\/jats:sec>","DOI":"10.5114\/aoms\/152338","type":"journal-article","created":{"date-parts":[[2022,8,30]],"date-time":"2022-08-30T11:59:34Z","timestamp":1661860774000},"page":"1395-1398","source":"Crossref","is-referenced-by-count":4,"title":["Hepatitis E - epidemiology and clinical course in the largest cohort in the Czech Republic"],"prefix":"10.5114","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2946-658X","authenticated-orcid":false,"given":"Mat\u00fa\u0161","family":"Mihal\u010din","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, Faculty of Medicine, Masaryk University, Brno, Czech Republic"},{"name":"Department of Infectious Diseases, University Hospital Brno, Brno, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9639-2541","authenticated-orcid":false,"given":"Libuse","family":"Husova","sequence":"additional","affiliation":[{"name":"Centre of Cardiovascular and Transplant Surgery Brno, Brno, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6281-5799","authenticated-orcid":false,"given":"Petra","family":"Vasickova","sequence":"additional","affiliation":[{"name":"Veterinary Research Institute, Brno, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6759-7708","authenticated-orcid":false,"given":"Marcel","family":"Bena","sequence":"additional","affiliation":[{"name":"Veterinary Research Institute, Brno, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5501-6219","authenticated-orcid":false,"given":"Petr","family":"Husa","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Faculty of Medicine, Masaryk University, Brno, Czech Republic"},{"name":"Department of Infectious Diseases, University Hospital Brno, Brno, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3061","published-online":{"date-parts":[[2022,8,30]]},"container-title":["Archives of Medical Science"],"original-title":[],"link":[{"URL":"https:\/\/www.archivesofmedicalscience.com\/pdf-152338-78030","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.archivesofmedicalscience.com\/pdf-152338-78030","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,30]],"date-time":"2022-08-30T11:59:39Z","timestamp":1661860779000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.archivesofmedicalscience.com\/Hepatitis-E-epidemiology-and-clinical-course-in-the-largest-cohort-in-the-Czech-Republic,152338,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,30]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022]]}},"alternative-id":["152338"],"URL":"https:\/\/doi.org\/10.5114\/aoms\/152338","relation":{},"ISSN":["1734-1922","1896-9151"],"issn-type":[{"value":"1734-1922","type":"print"},{"value":"1896-9151","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,30]]}}}