{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T00:18:22Z","timestamp":1787962702515,"version":"build-2784847793"},"reference-count":0,"publisher":"Termedia Sp. z.o.o.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Med Sci"],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>The blood urea nitrogen to serum albumin ratio (BAR) may serve as a prognostic marker. This study evaluated its association with clinical outcomes in patients with acute pancreatitis (AP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>We performed a retrospective cohort analysis using data from the MIMIC-IV 2.2 database, including 650 patients diagnosed with AP. The primary outcomes were 90-day and 365-day mortality.Cox proportional hazards models assessed the relationship between BAR and mortality.Restricted cubic spline (RCS) analysis examined the non-linear relationship. Receiver operating characteristic (ROC) curves were generated to evaluate the predictive performance of BAR for mortality. Kaplan-Meier(KM) survival curves were generated to compare outcomes across the BAR groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the 650 patients, the mortality rates at 90 days and 365 days were 21.2% and 26.2%, respectively. Higher BAR levels correlated with increased 90-day and 365-day mortality (P &lt; 0.001). BAR had hazard ratios of (HR 1.04, 95% CI 1.02\u20131.06) for 90-day and (HR 1.04, 95% CI 1.02\u20131.05) for 365-day mortality. ROC analysis revealed BAR\u2019s AUC was 0.738 for 90-day and 0.714 for 365-day mortality. Subgroup and sensitivity analyses indicated stable results across various conditions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Elevated BAR is significantly associated with increased mortality in AP patients, indicating its potential as a valuable prognostic marker in critical care settings.<\/jats:p><\/jats:sec>","DOI":"10.5114\/aoms\/204369","type":"journal-article","created":{"date-parts":[[2025,6,8]],"date-time":"2025-06-08T09:47:03Z","timestamp":1749376023000},"source":"Crossref","is-referenced-by-count":1,"title":["Increased blood urea nitrogen to serum albumin ratio are associated with poor prognosis in patients with acute pancreatitis: A retrospective cohort study"],"prefix":"10.5114","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-0315-8279","authenticated-orcid":true,"given":"Yun","family":"Huang","sequence":"first","affiliation":[{"name":"The First People\u2019s Hospital of Foshan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-9622-6376","authenticated-orcid":false,"given":"Chunyan","family":"Zhang","sequence":"additional","affiliation":[{"name":"The First People\u2019s Hospital of Foshan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3372-5061","authenticated-orcid":false,"given":"Meiqiu","family":"Li","sequence":"additional","affiliation":[{"name":"The First People\u2019s Hospital of Foshan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-2069-8481","authenticated-orcid":false,"given":"Jun","family":"Mei","sequence":"additional","affiliation":[{"name":"The First People\u2019s Hospital of Foshan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-7024-2098","authenticated-orcid":false,"given":"Yingxin","family":"Wu","sequence":"additional","affiliation":[{"name":"The First People\u2019s Hospital of Foshan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-8494-7327","authenticated-orcid":false,"given":"Xia","family":"XIANG","sequence":"additional","affiliation":[{"name":"The First People\u2019s Hospital of Foshan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3061","published-online":{"date-parts":[[2025,6,8]]},"container-title":["Archives of Medical Science"],"original-title":[],"link":[{"URL":"https:\/\/www.archivesofmedicalscience.com\/pdf-204369-125946","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.archivesofmedicalscience.com\/pdf-204369-125946","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,8]],"date-time":"2025-06-08T09:47:04Z","timestamp":1749376024000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.archivesofmedicalscience.com\/Increased-blood-urea-nitrogen-to-serum-albumin-ratio-are-associated-with-poor-prognosis,204369,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,8]]},"references-count":0,"alternative-id":["204369"],"URL":"https:\/\/doi.org\/10.5114\/aoms\/204369","relation":{},"ISSN":["1734-1922","1896-9151"],"issn-type":[{"value":"1734-1922","type":"print"},{"value":"1896-9151","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,8]]}}}