{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T02:23:57Z","timestamp":1785378237620,"version":"3.55.0"},"reference-count":0,"publisher":"Termedia Sp. z.o.o.","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Med Sci"],"published-print":{"date-parts":[[2019,10,8]]},"abstract":"<jats:p>As obesity becomes more common worldwide, the prevalence of obstructive sleep apnoea (OSA) continues to rise. Obstructive sleep apnoea is a\u00a0well-known disorder that causes chronic intermittent hypoxia (CIH), which is considered a\u00a0risk factor for atherosclerosis directly and indirectly. Ischaemic heart disease remains the leading cause of death. Most risk factors for atherosclerosis are well understood. However, other factors such as CIH are less well understood. Several studies have investigated the pathophysiology of CIH, attempting to uncover its link to atherosclerosis and to determine whether OSA treatment can be a\u00a0therapeutic modality to modify the risk for atherosclerosis. In this article, we will review the pathophysiology of OSA as an independent risk factor for cardiovascular disease and discuss the most common markers that have been studied. We will also examine the potential impact of OSA management as a\u00a0risk factor modifier on the reversibility of atherosclerosis.<\/jats:p>","DOI":"10.5114\/aoms.2019.88558","type":"journal-article","created":{"date-parts":[[2019,10,11]],"date-time":"2019-10-11T22:48:43Z","timestamp":1570834123000},"page":"1200-1212","source":"Crossref","is-referenced-by-count":14,"title":["Obstructive sleep apnoea and cardiovascular disease: a literature review"],"prefix":"10.5114","volume":"17","author":[{"given":"Hussein","family":"Assallum","sequence":"first","affiliation":[{"name":"Division of Pulmonary, Critical Care, and Sleep Medicine, New York Medical College, Valhalla, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian Yue","family":"Song","sequence":"additional","affiliation":[{"name":"Division of Pulmonary, Critical Care, and Sleep Medicine, New York Medical College, Valhalla, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilbert","family":"Aronow","sequence":"additional","affiliation":[{"name":"Division of Cardiology, New York Medical College, Valhalla, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dipak","family":"Chandy","sequence":"additional","affiliation":[{"name":"Division of Pulmonary, Critical Care, and Sleep Medicine, New York Medical College, Valhalla, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3061","published-online":{"date-parts":[[2019,10,8]]},"container-title":["Archives of Medical Science"],"original-title":[],"link":[{"URL":"https:\/\/www.archivesofmedicalscience.com\/pdf-109809-68015","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.archivesofmedicalscience.com\/pdf-109809-68015","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,8]],"date-time":"2021-09-08T11:32:47Z","timestamp":1631100767000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.archivesofmedicalscience.com\/Obstructive-sleep-apnoea-and-cardiovascular-disease-a-literature-review,109809,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,8]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021]]}},"alternative-id":["109809"],"URL":"https:\/\/doi.org\/10.5114\/aoms.2019.88558","relation":{},"ISSN":["1734-1922","1896-9151"],"issn-type":[{"value":"1734-1922","type":"print"},{"value":"1896-9151","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,8]]}}}