{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T22:50:46Z","timestamp":1782255046880,"version":"3.54.5"},"reference-count":13,"publisher":"Termedia Sp. z.o.o.","issue":"1","license":[{"start":{"date-parts":[[2019,4,15]],"date-time":"2019-04-15T00:00:00Z","timestamp":1555286400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0\/"},{"start":{"date-parts":[[2019,4,15]],"date-time":"2019-04-15T00:00:00Z","timestamp":1555286400000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0\/"},{"start":{"date-parts":[[2019,4,15]],"date-time":"2019-04-15T00:00:00Z","timestamp":1555286400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cent Eur J Immunol"],"abstract":"<jats:p>Coeliac disease (CD) is an autoimmune disorder of the small intestine triggered by ingested gluten from barley, rye and wheat. It can be associated with other autoimmune conditions, such as type 1 diabetes, autoimmune thyroiditis and hepatitis, Sj\u00f6gren\u2019s syndrome and IgA nephropathy (IgAN). We describe here a case of a 24-year-old man with the above-mentioned atypical form of coeliac disease for whom the diagnosis started with renal disorder. The diagnosis of nephrotic syndrome was established and the coexistence with CD was also suspected. In fact, immunoglobulin (Ig) A and IgG antibodies against endomysium and against gliadin were detected in serum of the patient and the endoscopic biopsy of the duodenum revealed stage 3B CD. Percutaneous kidney biopsy was also performed. Class I IgAN was diagnosed. Gluten-free diet, ACE inhibitor and oral iron were introduced to the patient. The improvement of clinical and laboratory disorders of CD as well as gradual remission of the nephrotic syndrome were observed. In conclusion, there may be a small group of patients with IgAN coexisting with CD in whom a gluten-free diet seems to be the treatment of choice for the resolution of kidney disease.<\/jats:p>","DOI":"10.5114\/ceji.2019.84021","type":"journal-article","created":{"date-parts":[[2019,4,16]],"date-time":"2019-04-16T09:01:17Z","timestamp":1555405277000},"page":"106-108","source":"Crossref","is-referenced-by-count":18,"title":["IgA nephropathy associated with coeliac disease"],"prefix":"10.5114","volume":"44","author":[{"given":"Ireneusz","family":"Habura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarzyna","family":"Fiedorowicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aldona","family":"Wo\u017aniak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilona","family":"Idasiak-Piechocka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pawe\u0142","family":"Kosikowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrzej","family":"Oko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3061","published-online":{"date-parts":[[2019,4,15]]},"reference":[{"key":"ref-1549390","doi-asserted-by":"crossref","first-page":"1333s","DOI":"10.1056\/NEJMcps1301321","article-title":"Against the Grain","volume":"371","author":"Riksfjord Hamnvik OP","year":"2014","unstructured":"Riksfjord Hamnvik OP, Saldana F, Levy BD, et al. (2014). Against the Grain. N Engl J Med. 371: 1333s-1338s.","journal-title":"N Engl J Med"},{"key":"ref-1549391","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1097\/MCG.0b013e318284792e","article-title":"Increased risk of IgA Nephropathy among individuals with celiac disease","volume":"47","author":"Welender A","year":"2013","unstructured":"Welender A, Sundelin B, Fored M, et al. (2013). Increased risk of IgA Nephropathy among individuals with celiac disease. J Clin Gastroenterol. 47: 678-683.","journal-title":"J Clin Gastroenterol"},{"key":"ref-1549392","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1136\/gutjnl-2011-300134","article-title":"Increased risk of end-stage renal disease in individuals with celiac disease","volume":"61","author":"Welender A","year":"2012","unstructured":"Welender A, Prutz KG, Fored M, et al. (2012). Increased risk of end-stage renal disease in individuals with celiac disease. 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Nephrol Dial Transplant. 20: 342-348.","journal-title":"Nephrol Dial Transplant"},{"key":"ref-1549395","first-page":"209","volume-title":"Clinical Practice Guidelines for Glomerulonephritis","author":"KDIGO","year":"2012","unstructured":"KDIGO. (2012). Clinical Practice Guidelines for Glomerulonephritis. 2: 209-217."},{"key":"ref-1549396","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1093\/ndt\/8.12.1382","article-title":"A case of IgA nephropathy with coeliac disease responding to a gluten-free diet","volume":"8","author":"Woodrow G","year":"1993","unstructured":"Woodrow G, Innes A, Boyd SM, Burden RP. (1993). A case of IgA nephropathy with coeliac disease responding to a gluten-free diet. Nephrol Dial Transplant. 8: 1382-1383.","journal-title":"Nephrol Dial Transplant"},{"key":"ref-1549397","first-page":"161","article-title":"A case report: a patient with IgA nephropathy and coeliac disease. Complete clinical remission following gluten-free diet","volume":"2","author":"Koivuviita N","year":"2009","unstructured":"Koivuviita N, Tertti R, Heiro M, Metsarinne K. (2009). A case report: a patient with IgA nephropathy and coeliac disease. Complete clinical remission following gluten-free diet. Nephrol Dial Transplant. 2: 161-163.","journal-title":"Nephrol Dial Transplant"},{"key":"ref-1549398","doi-asserted-by":"crossref","first-page":"2274","DOI":"10.1046\/j.1523-1755.1999.00471.x","article-title":"Small bowel T cells, HLA class II antigen DR, and GroEL stress protein in IgA nephropathy","volume":"55","author":"Rantala I","year":"1999","unstructured":"Rantala I, Collin P, Holm K, et al. (1999). Small bowel T cells, HLA class II antigen DR, and GroEL stress protein in IgA nephropathy. 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