{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T10:47:58Z","timestamp":1782211678345,"version":"3.54.5"},"reference-count":17,"publisher":"Termedia Sp. z.o.o.","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pol J Pathol"],"abstract":"<jats:p>We present a case of a 52-year-old man with myasthenia gravis and a mediastinal tumor who was admitted to our hospital for surgical treatment. The pathologic examination of the resected tumor revealed a very rare case of a collision tumor: a B1B2 thymoma and a small lymphocytic lymphoma. Flow cytometry of the peripheral blood revealed the presence of a small number of leukemic cells. After postoperative irradiation of the mediastinum and chemotherapy a complete response in both diseases was achieved. The case confirms that a pathologist should always be aware that two different neoplasms can coexist in rare cases.<\/jats:p>","DOI":"10.5114\/pjp.2017.67620","type":"journal-article","created":{"date-parts":[[2017,5,31]],"date-time":"2017-05-31T07:17:51Z","timestamp":1496215071000},"page":"75-81","source":"Crossref","is-referenced-by-count":6,"title":["Two neoplasms rich in small lymphocytes, B1B2 thymoma and small lymphocytic lymphoma, intermingled in one tumor mass. A case report"],"prefix":"10.5114","volume":"68","author":[{"given":"Malgorzata","family":"Szolkowska","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renata","family":"Langfort","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Winiarski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacek","family":"Zaremba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Prochorec-Sobieszek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grzegorz","family":"Rymkiewicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr","family":"Jaskiewicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dariusz M.","family":"Kowalski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3061","published-online":{"date-parts":[[2017,5,23]]},"reference":[{"key":"ref-1702245","doi-asserted-by":"crossref","unstructured":"Granato F, Ambrosio MR, Spina D, et al. Patients with thymomas have an increased risk of developing additional malignancies: lack of immunological surveillance? Histopathology 2012; 60: 437-442.","DOI":"10.1111\/j.1365-2559.2011.04111.x"},{"key":"ref-1702246","unstructured":"Filosso PL, Galassi C,."},{"key":"ref-1702247","doi-asserted-by":"crossref","unstructured":"Ruffini E, et al. Thymoma and the increased risk of developing extrathymic malignancies: a multicentre study. Eur J Cardiothorac Surg 2013; 44: 219-224.","DOI":"10.1093\/ejcts\/ezs663"},{"key":"ref-1702248","doi-asserted-by":"crossref","unstructured":"Weksler B, Nason KS, Mackey D, et al. Thymomas and extrathymic cancers. Ann Thorac Surg 2012; 93: 884-888.","DOI":"10.1016\/j.athoracsur.2011.05.089"},{"key":"ref-1702249","unstructured":"M\u00fcller-Hermelink HK, Engel\u2028 P, Kuo TT, et al. Tumours of the Thymus. In: Travis WD, Brambilla E, Muller-Hermelink HK, et al. (eds.). WHO Classification of Tumours. Pathology and Genetics. Tumours of the Lung, Pleura, Thymus and Heart. IARC Press, Lyon 2004;145-248."},{"key":"ref-1702250","doi-asserted-by":"crossref","unstructured":"Str\u00f6bel P, Marino M, Feuchtenberger M, et al. Micronodular thymoma: an epithelial tumour with abnormal chemokine expression setting the stage for lymphoma development. J Pathol 2005, 207: 72-82.","DOI":"10.1002\/path.1808"},{"key":"ref-1702251","unstructured":"Swerdlow SH, Campo E, Harris NL, et al. (eds.) WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. 4rd ed. IARC, Lyon 2008."},{"key":"ref-1702252","doi-asserted-by":"crossref","unstructured":"Friedman HD, Inman DA, Hutchison RE, Poiesz BJ. Concurrent invasive thymoma and T-cell lymphoblastic leukemia and lymphoma. A case report with necropsy findings and literature review of thymoma and associated hematologic neoplasm. 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Two malignant tumours in the anterior mediastinum positive for CD5. BMJ Case Rep 2010; 2010: pii: bcr0920092289.","DOI":"10.1136\/bcr.09.2009.2289"},{"key":"ref-1702261","doi-asserted-by":"crossref","unstructured":"Slager SL, Benavente Y, Blair A, et al. Medical history, lifestyle, family history, and occupational risk factors for chronic lymphocytic leukemia\/small lymphocytic lymphoma: the InterLymph Non-Hodgkin Lymphoma Subtypes Project. 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