{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T10:51:40Z","timestamp":1782211900621,"version":"3.54.5"},"reference-count":23,"publisher":"Termedia Sp. z.o.o.","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pol J Pathol"],"abstract":"<jats:p>In our pilot study we have aimed to assess interlaboratory variability of\u00a0cytological diagnoses in selected laboratories participating in the\u00a0Polish Cervical Cancer Screening Programme (CCSP) to establish grounds for certification system for cytodiagnosticians and to monitor the\u00a0quality of\u00a0services. Set of\u00a050 selected Pap smears, previously reassessed by an\u00a0expert on the\u00a0grounds of\u00a0clinical, colposcopic and histological data was blinded and sent to 15 laboratories in Poland with request for evaluation according to routine practice according to the\u00a0Bethesda 2001 system. Concordance with expert diagnoses reached a\u00a0median of\u00a082% (range: 66% to 92%), with median unweighted \u03ba coefficient at \u03ba\u00a0=\u00a00.67 (range 0.40 to 0.86) depending on laboratory. This indicates substantial agreement among laboratories, however with essential differences in proper evaluation in some outlying laboratories.&lt;br \/&gt;\nAgreement was highest in samples with high-grade, lower for low-grade abnormalities. Slides with ASC-US and ASC-H expert diagnoses were most troubling for cytodiagnosticians. Sets of\u00a0highly selected cytological slides with expert diagnoses may serve as a\u00a0tool in the\u00a0process of\u00a0comprehensive periodic recertification of\u00a0cytodiagnosticians in the\u00a0screening programme. A\u00a0benchmark level of\u00a0agreement with expert diagnoses should be established to guide corrective actions for cytodiagnosticians with lowest agreement.<\/jats:p>","DOI":"10.5114\/pjp.2021.106445","type":"journal-article","created":{"date-parts":[[2021,7,4]],"date-time":"2021-07-04T15:12:10Z","timestamp":1625411530000},"page":"75-83","source":"Crossref","is-referenced-by-count":1,"title":["Interlaboratory agreement in assessment of gynaecological cytology in Cervical Cancer Screening Programme in Poland \u2013 a pilot evaluation"],"prefix":"10.5114","volume":"72","author":[{"given":"Kinga","family":"Zalewska-Otwinowska","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Macios","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarzyna","family":"Komerska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ma\u0142gorzata","family":"Rekosz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrzej","family":"Nowakowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3061","published-online":{"date-parts":[[2021,5,31]]},"reference":[{"key":"ref-1695257","unstructured":"Bernard W. Stewart and Christopher P. Wild. IARC: World cancer report 2014, Lyon 2014."},{"key":"ref-1695258","unstructured":"World Health Organization: Cervical cancer, Geneva 2018. Available at: https:\/\/www.who.int\/cancer\/prevention\/diagnosis-screening\/cervical-cancer\/en\/ (access 16.07.2019)."},{"key":"ref-1695259","unstructured":"Wojciechowska U, Czaderny K, Ciuba A, et al. Cancer in Poland in 2016. Polish National Cancer Registry, Department of\u00a0Epidemiology and Cancer Prevention 2018."},{"key":"ref-1695260","unstructured":"Nowakowski A, Wojciechowska U, Wieszczy P, et al. Trends in cervical cancer incidence and mortality in Poland: is there an\u00a0impact of\u00a0the\u00a0introduction of\u00a0the\u00a0organised screening? Eur."},{"key":"ref-1695261","doi-asserted-by":"crossref","unstructured":"J Epidemiol 2017; 32: 529-532.","DOI":"10.1007\/s10654-017-0291-6"},{"key":"ref-1695262","unstructured":"The Maria Sklodowska-Curie National Research Institute of\u00a0Oncology, Warsaw: National Cancer Registry. Available at: http:\/\/onkologia.org.pl\/nowotwory-szyjki-macicy-kobiet\/ (access 16.07.2019)."},{"key":"ref-1695263","unstructured":"Council of\u00a0the\u00a0European Union (2003). Council recommendation of\u00a02 December 2003 on cancer screening (2003\/878\/EC). Off J Eur Union 2003; L 327: 34-38."},{"key":"ref-1695264","unstructured":"Arbyn M, Anttila A, Jordan J, et al. (eds.). European guidelines for quality assurance in cervical cancer screening. 2nd edition. International Agency for Research on Cancer 2008."},{"key":"ref-1695265","doi-asserted-by":"crossref","unstructured":"Gultekin M, Karaca MZ, Kucukyildiz I, et al. 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PLoS One 2019; 14: e0217108.","DOI":"10.1371\/journal.pone.0217108"},{"key":"ref-1695269","doi-asserted-by":"crossref","unstructured":"Zelazik M, Michalska A, Radowicz-Chil A, et al. Unified cytological reports determine the\u00a0clinical management. Medical Studies 2019; 35: 147-152.","DOI":"10.5114\/ms.2019.86334"},{"key":"ref-1695270","doi-asserted-by":"crossref","unstructured":"Nayar R, Wilbur DC. The\u00a0Bethesda System for Reporting Cervical Cytology: A\u00a0Historical Perspective. Acta Cytol 2017; 61: 359-372.","DOI":"10.1159\/000477556"},{"key":"ref-1695271","unstructured":"Polskie Towarzystwo Ginekologiczne: Rekomendacje PTG dotycz\u00b9ce diagnostyki, profilaktyki i wczesnego wykrywania raka szyjki macicy. Ginekol Pol  2006; 77: 655-659."},{"key":"ref-1695272","unstructured":"StataCorp. 2017. Stata Statistical Software: Release 15. College Station, TX: StataCorp LLC."},{"key":"ref-1695273","doi-asserted-by":"crossref","unstructured":"Baena A, Guevara E, Almonte M, et al. 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Accuracy of\u00a0cervical cytology: comparison of\u00a0diagnoses of\u00a0100 Pap smears read by four pathologists at three hospitals in Norway. BMC Clin Pathol 2017; 17: 18.","DOI":"10.1186\/s12907-017-0058-8"},{"key":"ref-1695277","doi-asserted-by":"crossref","unstructured":"Stoler MH, Schiffman M. Interobserver reproducibility of\u00a0cervical cytologic and histologic interpretations: realistic estimates from the\u00a0ASCUS-LSIL Triage Study. JAMA 2001; 285: 1500-1505.","DOI":"10.1001\/jama.285.11.1500"},{"key":"ref-1695278","doi-asserted-by":"crossref","unstructured":"T\u00fcrkmen IC, Ba\u015fs\u00fcll\u00fc N, Bing\u00f6l B, et al. Interobserver variability in cervical smears from patients with a\u00a0history of\u00a0abnormal cytology: comparison of\u00a0conventional Pap smears and liquid-based cytology. Erciyes Med J 2013; 1: 13-17.","DOI":"10.5152\/etd.2013.03"},{"key":"ref-1695279","doi-asserted-by":"crossref","unstructured":"Wright TC Jr, Stoler MH, Behrens CM, et al. Interlaboratory variation in the\u00a0performance of\u00a0liquid-based cytology: insights from the\u00a0ATHENA trial. Int\u00a0J\u00a0Cancer 2014; 134: 1835-1843.","DOI":"10.1002\/ijc.28514"}],"container-title":["Polish Journal of Pathology"],"original-title":["Zgodno\u015b\u0107 rozpozna\u0144 cytologicznych mi\u0119dzy laboratoriami realizuj\u0105cymi Program Profilaktyki Raka Szyjki Macicy w Polsce - pilota\u017c"],"link":[{"URL":"https:\/\/www.polishjournalofpathology.com\/pdf-129258-136722","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.polishjournalofpathology.com\/pdf-129258-136722","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T10:43:52Z","timestamp":1782211432000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.polishjournalofpathology.com\/Interlaboratory-agreement-in-assessment-of-gynaecological-cytology-in-Cervical-Cancer,129258,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,31]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021]]}},"alternative-id":["129258"],"URL":"https:\/\/doi.org\/10.5114\/pjp.2021.106445","relation":{},"ISSN":["1233-9687","2084-9869"],"issn-type":[{"value":"1233-9687","type":"print"},{"value":"2084-9869","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,31]]}}}