{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T11:46:32Z","timestamp":1782215192116,"version":"3.54.5"},"reference-count":16,"publisher":"Termedia Sp. z.o.o.","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pol J Pathol"],"abstract":"<jats:p>Uveal melanoma is the most common primary malignancy of the eye in adults. It may involve the choroid and ciliary body, and in only 2-3% of cases it involves the iris. &lt;br \/&gt;\nWe present a case of a 56-year-old patient with a 6-year history of unilateral, inflammatory, refractory glaucoma of the right eye. Due to acquired heterochromia and heterogeneous thickness of the iris, iris melanoma was suspected, but the incisional biopsy did not confirm the diagnosis. In the next months, the lesion enlarged and the eye globe was enucleated. Histopathological examination revealed an iridociliary melanoma with annular growth pattern.<\/jats:p>","DOI":"10.5114\/pjp.2021.111777","type":"journal-article","created":{"date-parts":[[2022,1,20]],"date-time":"2022-01-20T04:38:20Z","timestamp":1642653500000},"page":"267-271","source":"Crossref","is-referenced-by-count":1,"title":["Iris melanoma with ciliary body infiltration presenting as a presumed chronic unilateral inflammatory glaucoma. The challenges of iris tumor biopsy assessment"],"prefix":"10.5114","volume":"72","author":[{"given":"Agata","family":"Stodolska-Nowak","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wojciech","family":"Adamski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agata","family":"Br\u0105zert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacek","family":"Sygut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrzej","family":"Marsza\u0142ek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iwona","family":"Rospond-Kubiak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3061","published-online":{"date-parts":[[2022,1,19]]},"reference":[{"key":"ref-1694516","unstructured":"Shields JA, Shields CL. Intraocular Tumors: A Text and Atlas. Philadelphia: WB Saunders, 1992; 61-84."},{"key":"ref-1694517","doi-asserted-by":"crossref","unstructured":"Shields CL, Shields JA, Materin M, et al. Iris melanoma: risk factors for metastasis in 169 consecutive patients. Ophthalmology 2001; 108: 172-178.","DOI":"10.1016\/S0161-6420(00)00449-8"},{"key":"ref-1694518","doi-asserted-by":"crossref","unstructured":"Demirci H, Shields CL, Shields JA, et al. Ring melanoma of the ciliary body: report on twenty-three patients. Retina 2002; 22: 698-706.","DOI":"10.1097\/00006982-200212000-00003"},{"key":"ref-1694519","doi-asserted-by":"crossref","unstructured":"McLean IW, Foster WD, Zimmerman LE, et al. Modifications of Callender\u2019s classification of uveal melanoma at the Armed Forces Institute of Pathology. Am J Ophthalmol 1983; 96: 502-509.","DOI":"10.1016\/S0002-9394(14)77914-0"},{"key":"ref-1694520","doi-asserted-by":"crossref","unstructured":"V\u00e1squez LM, Pavlin CJ, McGowan H, et al. Ring melanoma of the ciliary body: clinical and ultrasound biomicroscopic characteristics. Can J Ophthalmol 2008, 43: 229-233.","DOI":"10.3129\/i08-025"},{"key":"ref-1694521","doi-asserted-by":"crossref","unstructured":"Stadigh A, Puska P, Vesti E, et al. Ring melanoma of the anterior chamber angle as a mimicker of pigmentary glaucoma. Surv Ophthalmol 2017; 62: 670-676.","DOI":"10.1016\/j.survophthal.2017.01.007"},{"key":"ref-1694522","doi-asserted-by":"crossref","unstructured":"Read RW, Zamir E, Rao NA. Neoplastic masquerade syndromes. Surv Ophthalmol 2002; 47: 81-124.","DOI":"10.1016\/S0039-6257(01)00305-8"},{"key":"ref-1694523","doi-asserted-by":"crossref","unstructured":"Chaudhry IM. Iris ring melanoma masquerading as pigmentary glaucoma. Arch Ophthalmol 1997; 115: 1480.","DOI":"10.1001\/archopht.1997.01100160650029"},{"key":"ref-1694524","doi-asserted-by":"crossref","unstructured":"Tay E, Cree IA, Hungerford J, Franks W. Recurrence of treated ciliary body melanoma following trabeculectomy. Clin Exp Ophthalmol 2009; 37: 503-505.","DOI":"10.1111\/j.1442-9071.2009.02069.x"},{"key":"ref-1694525","doi-asserted-by":"crossref","unstructured":"Grossniklaus HE, Brown RH, Stulting RD, et al. Iris melanoma seeding through a trabeculectomy site. Arch Ophthalmol 1990; 108: 1287-1290.","DOI":"10.1001\/archopht.1990.01070110103033"},{"key":"ref-1694526","doi-asserted-by":"crossref","unstructured":"Demirci H, Shields CL, Shields JA, et al. Ring melanoma of the anterior chamber angle: a report of fourteen cases. Am J Ophthalmol 2001; 132: 336-342.","DOI":"10.1016\/S0002-9394(01)01051-0"},{"key":"ref-1694527","doi-asserted-by":"crossref","unstructured":"Gokhale R, Medina CA, Biscotti CV, et al. Diagnostic fine-needle aspiration biopsy for iris melanoma. Asia Pac J Ophthalmol 2015; 4: 89-91.","DOI":"10.1097\/APO.0000000000000083"},{"key":"ref-1694528","doi-asserted-by":"crossref","unstructured":"Finger PT, Latkany P, Kurli M, Iacob C. The Finger iridectomy technique: small incision biopsy of anterior segment tumours.Br J Ophthalmol 2005; 89: 946-949.","DOI":"10.1136\/bjo.2004.062653"},{"key":"ref-1694529","doi-asserted-by":"crossref","unstructured":"Grossniklaus HE. Fine-needle aspiration biopsy of the iris. Arch Ophthalmol 1992; 110: 969Y976.","DOI":"10.1001\/archopht.1992.01080190075033"},{"key":"ref-1694530","doi-asserted-by":"crossref","unstructured":"Mudhar HS, Saunders E, Rundle P, et al. The in vivo modulatory effects of an anterior-chamber microenvironment on uveal melanoma. Br J Ophthalmol 2008; 93: 535-540.","DOI":"10.1136\/bjo.2008.147314"},{"key":"ref-1694531","doi-asserted-by":"crossref","unstructured":"Matthews BJ, Mudhar HS, Rennie IG. Trans-corneal fine cannula aspiration: Rycroft cannula aspiration technique for sampling iris tumours. 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