{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T11:48:12Z","timestamp":1782215292551,"version":"3.54.5"},"reference-count":19,"publisher":"Termedia Sp. z.o.o.","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pol J Pathol"],"abstract":"<jats:p>The mermaid syndrome, also known as sirenomelia, is considered an extremely rare congenital developmental disorder characterized by anomalies of the lower spine and lower limbs. Affected babies are born with partial or total leg fusion. Sirenomelia is thought to affect one in every 60,000 to 100,000 infants.&lt;br \/&gt;\nWe report a\u00a0case of sirenomelia occurring in a\u00a028-year-old multiparous woman, a\u00a0heavy smoker with gestational diabetes. In the other 5 pregnancies, however, she gave birth to normal babies. The post mortem examination completed  the diagnosis, revealing also multiple malformations of several systems: respiratory, gastro-intestinal, genito-urinary and cardiovascular.&lt;br \/&gt;\nIn our full term neonate case with grade VI sirenomelia, the presence of a\u00a0single umbilical artery plus the abdominal aorta with an aberrant trajectory that ends  in the umbilical cord differentiates this condition from caudal regression syndrome and also explains the under-development of pelvic organs (secondary to vascular steal phenomena).<\/jats:p>","DOI":"10.5114\/pjp.2022.124494","type":"journal-article","created":{"date-parts":[[2023,1,30]],"date-time":"2023-01-30T02:37:43Z","timestamp":1675046263000},"page":"277-280","source":"Crossref","is-referenced-by-count":3,"title":["Sirenomelia with associated systemic anomalies \u2013  an autopsy report in a\u00a0full term neonate"],"prefix":"10.5114","volume":"73","author":[{"given":"Vesa Alexandra","family":"Alina","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Octavian","family":"Maghiar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romina","family":"Cuc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Popescu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramona","family":"Dorobantu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Maghiar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ovidiu","family":"Pop","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Boros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3061","published-online":{"date-parts":[[2023,1,10]]},"reference":[{"key":"ref-1693139","doi-asserted-by":"crossref","unstructured":"Sahu L, Singh S, Gandhi G, Agarwal K. Sirenomelia: a\u00a0case report with literature review. Int J Reprod Contracept Obstet Gynecol 2013; 2: 430-432.","DOI":"10.5455\/2320-1770.ijrcog20130936"},{"key":"ref-1693140","unstructured":"Ramesh Reddy K, Srinivas S, Kumar S, et al. Sirenomelia: a\u00a0rare presentation. J Neonatal Surg 2012; 1: 7."},{"key":"ref-1693141","doi-asserted-by":"crossref","unstructured":"Orioli IM, Amar E, Arteaga-Vazque J, et al. Sirenomelia:  an epidemiologic study in a\u00a0large dataset from the international clearinghouse of birth defects surveillance and research, and literature review, Am J Med Genet C Semin Med Genet 2011; 157C: 358-373.","DOI":"10.1002\/ajmg.c.30324"},{"key":"ref-1693142","doi-asserted-by":"crossref","unstructured":"Ramphul K, Mejias G, Ramphul-Sicharam Y. Mermaid syndrome: a\u00a0case report in Mauritius. Cureus 2018; 10: e2210.","DOI":"10.7759\/cureus.2210"},{"key":"ref-1693143","doi-asserted-by":"crossref","unstructured":"Kavunga EK, Bunduki GK, Mumbere M, Masumbuko CK. Sirenomelia associated with an anterior abdominal wall defect: a\u00a0case report. J Med Case Rep 2019; 13: 213-218.","DOI":"10.1186\/s13256-019-2162-0"},{"key":"ref-1693144","doi-asserted-by":"crossref","unstructured":"Joshi R, Duomai VK, Sangma B. Sirenomelia, the mermaid baby: a\u00a0case report. Int J Reprod Contracept Obstet Gynecol 2019; 8: 4609-4611.","DOI":"10.18203\/2320-1770.ijrcog20194907"},{"key":"ref-1693145","doi-asserted-by":"crossref","unstructured":"Lucas LL, Morava E, Klein WM,\u00a0Schepens-Franke AN,  Oostra RJ. Sirenomelia: a\u00a0multi-systemic polytopic field defect with ongoing controversies. Birth Defects Res 2017; 109: 791-804.","DOI":"10.1002\/bdr2.1049"},{"key":"ref-1693146","doi-asserted-by":"crossref","unstructured":"Stevenson RE. Common pathogenesis for sirenomelia, OEIS complex, limb-body wall defect, and other malformations of caudal structures. Am J Med Genet A\u00a02021; 185: 1379-1387.","DOI":"10.1002\/ajmg.a.62103"},{"key":"ref-1693147","doi-asserted-by":"crossref","unstructured":"Duhamel B. From the mermaid to anal imperforation: the syndrome of caudal regression. Arch Dis Child 1961; 36: 152-154.","DOI":"10.1136\/adc.36.186.152"},{"key":"ref-1693148","unstructured":"Seidahmed MZ, Abdelbasit OB, Alhussein KA, et al. Sirenomelia and severe caudal regression syndrome. Saudi Med  J 2014; 35: S36-S43."},{"key":"ref-1693149","doi-asserted-by":"crossref","unstructured":"Morales-Rosell\u00f3 J, Loscalzo G, Buongiorno S, et al. Sirenomelia, case report and review of the literature. J Matern Fetal Neonatal Med 2022; 35: 1203-1206.","DOI":"10.1080\/14767058.2020.1742693"},{"key":"ref-1693150","doi-asserted-by":"crossref","unstructured":"Fadhlaoui A, Khrouf M, Gaigi S, Zhioua F, Chaker A.  The sirenomelia sequence: a\u00a0case history. Clin Med Insights Case Rep 2010; 3: 41-49.","DOI":"10.4137\/CCRep.S5347"},{"key":"ref-1693151","unstructured":"Verma RP. Genetics of sirenomelia, the mermaid syndrome. IntechOpen 2021."},{"key":"ref-1693152","doi-asserted-by":"crossref","unstructured":"Samal SK, Rathod S. Sirenomelia: the mermaid syndrome:  report of two cases. J Nat Sc Biol Med 2015; 6: 264-266.","DOI":"10.4103\/0976-9668.149227"},{"key":"ref-1693153","doi-asserted-by":"crossref","unstructured":"Kurosawa K, Tanoshima-Takei M, Yamamoto T, et al. Sirenomelia with a\u00a0de novo balanced translocation 46,X,t(X;16)(p11.23;p12.3). Congenit Anom (Kyoto) 2012; 52: 106-110.","DOI":"10.1111\/j.1741-4520.2011.00326.x"},{"key":"ref-1693154","doi-asserted-by":"crossref","unstructured":"Toni G, Grisolia G. Sirenomelia: a\u00a0review on embryogenic enviromental theories, novel three-dimensional ultrasound imaging and first trimester diagnosis in a\u00a0case of mosaic 69,XXX\/46,XX fetus. Arch Ginecol Obstet 2013; 288: 3-11.","DOI":"10.1007\/s00404-013-2847-3"},{"key":"ref-1693155","doi-asserted-by":"crossref","unstructured":"Ceylan Y, Do\u011fan Y, \u00d6zdemir S\u00d6, Y\u00fccesoy G. Prenatal diagnosis of sirenomelia in the first trimester: a\u00a0case report. Turk  J Obstet Gynecol 2016; 13: 50-52.","DOI":"10.4274\/tjod.90688"},{"key":"ref-1693156","doi-asserted-by":"crossref","unstructured":"Sepulveda W, Bornstein E, Andreeva E, et al. First-trimester sonographic diagnosis of sirenomelia: a\u00a0multicenter series  of 12 cases and review of the literature. Prenat Diagn 2020;  40: 626-634.","DOI":"10.1002\/pd.5667"},{"key":"ref-1693157","doi-asserted-by":"crossref","unstructured":"K\u00fc\u00e7\u00fck S, K\u00fc\u00e7\u00fck IG. Sirenomelia (mermaid syndrome): a\u00a0case report. Turk Patoloji Derg 2020; 36: 256-260.","DOI":"10.5146\/tjpath.2020.01491"}],"container-title":["Polish Journal of Pathology"],"original-title":[],"link":[{"URL":"https:\/\/www.polishjournalofpathology.com\/pdf-156642-136657","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.polishjournalofpathology.com\/pdf-156642-136657","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T10:57:00Z","timestamp":1782212220000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.polishjournalofpathology.com\/Sirenomelia-with-associated-systemic-anomalies-an-autopsy-report-in-a-full-term-neonate,156642,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,10]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022]]}},"alternative-id":["156642"],"URL":"https:\/\/doi.org\/10.5114\/pjp.2022.124494","relation":{},"ISSN":["1233-9687","2084-9869"],"issn-type":[{"value":"1233-9687","type":"print"},{"value":"2084-9869","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,10]]}}}