{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T11:49:13Z","timestamp":1782215353099,"version":"3.54.5"},"reference-count":6,"publisher":"Termedia Sp. z.o.o.","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pol J Pathol"],"abstract":"<jats:p>We present the\u00a0case of\u00a0a\u00a071-year-old patient, with vaginal bleeding, dyspnea, headache, loss of\u00a0appetite and weakness. Clinical examination revealed a\u00a0pediculated vaginal mass of\u00a025 mm diameter, of\u00a0dark-red color and soft spongy consistency, with an\u00a0ulcerated surface and originating from the\u00a0anterior wall, which was surgically removed. The\u00a0morphology was dominanted by large, round to polygonal tumor cells, arranged in a\u00a0predominantly tubulo-cystic architecture, surrounding numerous blood vessels that dominated the\u00a0appearance, suggesting a\u00a0perivascular epithelioid cell tumor (PEComa) or hemangioblastoma but the\u00a0presence of\u00a0pleomorphic nuclei, numerous mitoses together with immunohistochemistry helped for a\u00a0correct diagnosis of\u00a0vaginal .<\/jats:p>","DOI":"10.5114\/pjp.2023.132229","type":"journal-article","created":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T03:32:41Z","timestamp":1698204761000},"page":"216-218","source":"Crossref","is-referenced-by-count":0,"title":["Vaginal metastasis of\u00a0renal clear cell carcinoma: a\u00a0case report emphasizing the\u00a0role of\u00a0immunohistochemistry in differential diagnosis in the\u00a0absence of\u00a0a\u00a0clinical history"],"prefix":"10.5114","volume":"74","author":[{"given":"Simona","family":"Stolnicu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrei","family":"Patrichi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisc","family":"Rozsnyai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert A.","family":"Soslow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3061","published-online":{"date-parts":[[2023,10,25]]},"reference":[{"key":"ref-1691881","unstructured":"Perez CA, Gersell DJ, McGuire WP, et al. Vaginal cancer. In: Hoskins WJ, Perez CA, Young RC (ed.). Principles and practice of\u00a0gynecologic oncology. Lippincott, Williams and Wilkins, Philadelphia 2000; 811-840."},{"key":"ref-1691882","doi-asserted-by":"crossref","unstructured":"Allard JE, McBroom JW, Zahn CM, et al. Vaginal metastasis and thrombocytopenia from renal cell carcinoma. Gynecol Oncol 2004; 92: 970-973.","DOI":"10.1016\/j.ygyno.2003.11.046"},{"key":"ref-1691883","doi-asserted-by":"crossref","unstructured":"Tse JY, Wong JH, Lo KW, et al. Molecular genetic analysis of\u00a0the\u00a0von Hippel-Lindau disease tumor supressor gene in familial and sporaduc cerebellar hemangioblastomas. Am J Clin Pathol 1997; 107: 459-466.","DOI":"10.1093\/ajcp\/107.4.459"},{"key":"ref-1691884","unstructured":"Peham I. Hypernephrom der linken Niere mitein er Metastase in der Vagina. Zentralbl Gynak Ol 1906; 30: 724-725."},{"key":"ref-1691885","doi-asserted-by":"crossref","unstructured":"Ouellet S, Binette A, Nguyem A, et al. Metastatic renal cell carcinoma initially presenting with hematochezia and subsequently with vaginal bleeding: a\u00a0case report. BMC Urology 2018; 18: 4.","DOI":"10.1186\/s12894-018-0317-8"},{"key":"ref-1691886","doi-asserted-by":"crossref","unstructured":"Torne A, Pahisa J, Castelo-Branco C, et al. Solitary vaginal metastasis as a\u00a0presenting form of\u00a0unsuspected renal adenocarcinoma. Gynecol Oncol 1994; 52: 260-263.","DOI":"10.1006\/gyno.1994.1042"}],"container-title":["Polish Journal of Pathology"],"original-title":[],"link":[{"URL":"https:\/\/www.polishjournalofpathology.com\/pdf-169273-136610","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.polishjournalofpathology.com\/pdf-169273-136610","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T11:01:13Z","timestamp":1782212473000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.polishjournalofpathology.com\/Vaginal-metastasis-of-renal-clear-cell-carcinoma-a-case-report-emphasizing-the-role,169273,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,25]]},"references-count":6,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023]]}},"alternative-id":["169273"],"URL":"https:\/\/doi.org\/10.5114\/pjp.2023.132229","relation":{},"ISSN":["1233-9687","2084-9869"],"issn-type":[{"value":"1233-9687","type":"print"},{"value":"2084-9869","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,25]]}}}