{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T11:50:37Z","timestamp":1782215437221,"version":"3.54.5"},"reference-count":26,"publisher":"Termedia Sp. z.o.o.","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pol J Pathol"],"abstract":"<jats:p>Odontogenic keratocysts (OKC) are locally aggressive jaw lesions characterized by a\u00a0high recurrence rate. Vimentin 3 (VIM3), a\u00a0truncated splice variant of\u00a0full-length vimentin (VIMFL), has recently emerged as a\u00a0potential biomarker in odontogenic tumors. &lt;br \/&gt;\nHowever, its role in OKC and association with recurrence remain unexplored. Formalin-fixed paraffin-embedded samples from OKC (n = 25) and dentigerous cysts (DC) (n = 25) were analyzed. Immunohistochemical staining for VIM3, VIMFL, p53, and Ki-67 was performed. In parallel, reverse transcription-quantitative polymerase chain reaction was used to assess mRNA expression levels of\u00a0VIM3, VIMFL, and p53. &lt;br \/&gt;\nWhile VIM3 expression did not significantly differ between OKC and DC, recurrent OKC exhibited significantly higher VIM3 labeling indices compared to non-recurrent cases (p = 0.040). &lt;br \/&gt;\nThis study demonstrates, for the\u00a0first time, the\u00a0expression of\u00a0VIM3 in OKC. Although the\u00a0findings are promising, further research with larger cohorts and functional validation is required to clarify the\u00a0mechanistic role of\u00a0VIM3 in odontogenic cyst biology.<\/jats:p>","DOI":"10.5114\/pjp.2025.159041","type":"journal-article","created":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T07:37:59Z","timestamp":1770190679000},"page":"284-291","source":"Crossref","is-referenced-by-count":0,"title":["Vimentin 3 expression in odontogenic keratocysts \u2013 a\u00a0molecular and immunohistochemical study"],"prefix":"10.5114","volume":"76","author":[{"given":"Ipek Atak","family":"Secen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heike","family":"Goebel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emre","family":"Bar\u0131\u015f","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie Freifrau","family":"von Brandenstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sibel Elif","family":"G\u00fcltekin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3061","published-online":{"date-parts":[[2026,2,4]]},"reference":[{"key":"ref-1687445","doi-asserted-by":"crossref","unstructured":"Vered M, Wright JM. 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