{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T07:55:54Z","timestamp":1776239754041,"version":"3.50.1"},"reference-count":24,"publisher":"Termedia Sp. z.o.o.","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pol J Radiol"],"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Retrospective studies have explored the\u00a0association between computed tomography (CT)-derived secondary signs and renal pelvic urine density (RPUD) with postoperative infection after ureteroscopic lithotripsy (URSL). This study evaluated the\u00a0prognostic value of\u00a0these indicators in chronic kidney disease (CKD) patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and methods<\/jats:title>\n                    <jats:p>Clinical data of\u00a0patients undergoing URSL for ureteral calculi at two tertiary hospitals from June 2015 to June 2025 were retrospectively collected. Patients were categorized into infection and non-infection groups. Baseline demographics, stone characteristics, RPUD, perinephric fat stranding (PFS), tissue rim sign (TRS), CKD history, and intraoperative variables were compared. Independent predictors were identified via multivariate logistic regression, and a\u00a0nomogram was constructed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Postoperative infection occurred in 102 patients (12.6%). The\u00a0infection group had significantly higher rates of\u00a0positive preoperative urine culture, diabetes, larger stone diameter, longer operation time, advanced CKD stage, elevated RPUD, and increased incidence of\u00a0PFS and TRS (all p &lt; 0.05). Multivariate analysis confirmed these variables as independent risk factors. The\u00a0nomogram demonstrated strong discrimination (C-index = 0.932).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Elevated RPUD combined with positive CT secondary signs (PFS and TRS) is significantly associated with postoperative infection risk in CKD patients undergoing URSL. These easily obtainable non-contrast computed tomography-derived markers offer a\u00a0novel and practical approach for preoperative risk stratification, enabling individualized preventive strategies and surgical optimization in this high-risk population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.5114\/pjr\/217731","type":"journal-article","created":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T07:12:06Z","timestamp":1776237126000},"page":"154-162","source":"Crossref","is-referenced-by-count":0,"title":["Secondary signs combined with renal pelvis urine density on preoperative CT as a\u00a0predictor of\u00a0infection following ureteroscopic lithotripsy with chronic kidney disease"],"prefix":"10.5114","volume":"91","author":[{"given":"Mingbin","family":"Xu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zechun","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuming","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daoyuan","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chengyang","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3061","published-online":{"date-parts":[[2026,3,25]]},"reference":[{"key":"ref-1748925","doi-asserted-by":"publisher","DOI":"10.1186\/s12894-020-00754-8"},{"key":"ref-1748926","doi-asserted-by":"crossref","unstructured":"De La Rosette J, Denstedt J, Geavlete P, Keeley F, Matsuda T, Pearle M, et al. 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