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Furthermore, the integration of fusion imaging and artificial intelligence-driven pipelines has made ultrasound indispensable for guiding complex interventional procedures in real-time. \nIn parallel, emerging technologies like targeted microbubbles and ultrasound-targeted microbubble destruction are pushing the field toward molecular imaging and theranostics, turning ultrasound into an active participant in therapy. This review examines these clinical applications, takes a critical look at persistent hurdles, and identifies current research directions.<\/jats:p>","DOI":"10.5114\/pjr\/219104","type":"journal-article","created":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T08:20:11Z","timestamp":1782894011000},"page":"280-287","source":"Crossref","is-referenced-by-count":0,"title":["Current advancements and future directions in contrast-enhanced ultrasound (CEUS) in liver oncology: from quantification to theranostics"],"prefix":"10.5114","volume":"91","author":[{"given":"Agnieszka","family":"Czapska","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrzej","family":"Fedak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Jamro\u015b","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadeusz","family":"Popiela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3061","published-online":{"date-parts":[[2026,6,15]]},"reference":[{"key":"ref-1915547","doi-asserted-by":"crossref","unstructured":"Dietrich CF, Correas JM, Cui XW, Dong Y, Havre RF, Jenssen C, et al. 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