{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:25:47Z","timestamp":1783470347851,"version":"3.55.0"},"reference-count":12,"publisher":"Termedia Sp. z.o.o.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pol J Radiol"],"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>The aim of this retrospective study was to evaluate the correlation between D-dimer levels in positive thrombo\u00adembolic thoracic computed tomography (CT) with the diameter of the pulmonary trunk and to study the relation between the D-dimer and the uni- or bilateralism of the lesions and the presence of pulmonal trunk involvement. We also analysed gender-specific differences in patients with and without dilatation of the pulmonal trunk.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>A total of 100 acute care patients (50 men and 50 women) with positive thromboembolic multiple detector computed tomography of the thorax, performed on two modern CT scanners, were retrospectively studied. All thoracic CTs were evaluated by two expert radiologists, with attention paid to the diameter of the pulmonary trunk and the correlation of D-dimer level with the uni-or bilateralism of the lesions. We also analysed sex-specific correlations. All patients underwent multislice computed tomography-examination after applying 70 ml iodinated non-ionic contrast media. Graphpad Prism 8.1.1 software was used for statistical data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The \u201cstrongest\u201d weak correlation resulted between D-dimer levels and the axial diameter of the pulmonal trunk. Considering the correlation between the axial diameter of the pulmonal trunk and gender-related distributions, we found that female patients had higher axial diameters than men. Another weak relationship, almost zero, was found between the D-dimer level and gender. Regarding the correlation between the uni- or bilateralism of thromboembolism and the D-dimer levels, we also found a weak correlation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This retrospective study showed that D-dimer levels, the diameter of the pulmonal trunk, the location, and gender-related distributions have almost no correlation and are not significantly predictive in imaging.<\/jats:p><\/jats:sec>","DOI":"10.5114\/pjr.2019.88330","type":"journal-article","created":{"date-parts":[[2019,10,11]],"date-time":"2019-10-11T22:48:31Z","timestamp":1570834111000},"page":"347-352","source":"Crossref","is-referenced-by-count":5,"title":["Correlation of acute pulmonal embolism with D-dimer levels and the diameter of the pulmonary trunk in thoracic multislice computed tomography. A single-centre retrospective analysis of 100 patients"],"prefix":"10.5114","volume":"84","author":[{"given":"Sigmund","family":"Stuppner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Ruiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3061","published-online":{"date-parts":[[2019,9,13]]},"reference":[{"key":"ref-1140069","doi-asserted-by":"crossref","first-page":"3033","DOI":"10.1093\/eurheartj\/ehu283","article-title":"; Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC). 2014 ESC guidelines on the diagnosis and management of acute pulmonary embolism","volume":"35","author":"Konstantinides SV","year":"2014","unstructured":"Konstantinides SV, Torbicki A, Agnelli G, et al. (2014). ; Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC). 2014 ESC guidelines on the diagnosis and management of acute pulmonary embolism. Eur Heart J. 35: 3033-3069.","journal-title":"Eur Heart J"},{"key":"ref-1140070","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1148\/radiol.2452070397","article-title":"Management of suspected acute pulmonary embolism in the era of CT angiography: a statement from the Fleischner Society","volume":"245","author":"Remy-Jardin M","year":"2007","unstructured":"Remy-Jardin M, Pistolesi M, Goodman LR, et al. (2007). Management of suspected acute pulmonary embolism in the era of CT angiography: a statement from the Fleischner Society. 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J Am Coll Cardiol. 70: 2411-2420.","journal-title":"J Am Coll Cardiol"},{"key":"ref-1140073","doi-asserted-by":"crossref","first-page":"491","DOI":"10.4103\/1947-2714.143278","article-title":"Effectiveness of D-dimer as a screening test for venous thromboembolism: an update","volume":"6","author":"Pulivarthi S","year":"2014","unstructured":"Pulivarthi S, Gurram MK. (2014). Effectiveness of D-dimer as a screening test for venous thromboembolism: an update. N Am J Med Sci. 6: 491-499.","journal-title":"N Am J Med Sci"},{"key":"ref-1140074","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1161\/CIRCIMAGING.111.968610","article-title":"Reference values for normal pulmonary artery dimensions by noncontrast cardiac computed tomography: the Framingham Heart Study","volume":"5","author":"Truong QA","year":"2012","unstructured":"Truong QA, Massaro JM, Rogers IS, et al. (2012). Reference values for normal pulmonary artery dimensions by noncontrast cardiac computed tomography: the Framingham Heart Study. Circ Cardiovasc Imaging. 5: 147-154.","journal-title":"Circ Cardiovasc Imaging"},{"key":"ref-1140075","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1513\/AnnalsATS.201406-253PP","article-title":"Significance of main pulmonary artery dilation on imaging studies","volume":"11","author":"Raymond TE","year":"2014","unstructured":"Raymond TE, Khabbaza JE, Yadav R, Tonelli AR. (2014). Significance of main pulmonary artery dilation on imaging studies. Ann Am Thorac Soc. 11: 1623-1632.","journal-title":"Ann Am Thorac Soc"},{"key":"ref-1140076","doi-asserted-by":"crossref","first-page":"224","DOI":"10.14797\/mdcj-13-4-224","article-title":"Pulmonary arterial hypertension in women","volume":"13","author":"Memon HA","year":"2017","unstructured":"Memon HA, Park MH. (2017). Pulmonary arterial hypertension in women. Methodist Debakey Cardiovasc J. 13: 224-237.","journal-title":"Methodist Debakey Cardiovasc J"},{"key":"ref-1140077","doi-asserted-by":"crossref","first-page":"225","DOI":"10.21037\/cdt.2017.12.01","article-title":"Imaging of acute pulmonary embolism: an update","volume":"8","author":"Moore AJE","year":"2018","unstructured":"Moore AJE, Wachsmann J, Chamarthy MR, Panjikaran L, Tanabe Y, Rajiah P. (2018). Imaging of acute pulmonary embolism: an update. Cardiovasc Diagn Ther. 8: 225-243.","journal-title":"Cardiovasc Diagn Ther"},{"key":"ref-1140078","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1001\/jama.2014.2135","article-title":"Age-adjusted d-dimer cutoff levels to rule out pulmonary embolism: The adjust-pe study","volume":"311","author":"Righini M","year":"2014","unstructured":"Righini M, Van Es J, Den Exter PL, et al. (2014). Age-adjusted d-dimer cutoff levels to rule out pulmonary embolism: The adjust-pe study. 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