{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T23:48:48Z","timestamp":1789688928964,"version":"4.0.1"},"reference-count":27,"publisher":"Termedia Sp. z.o.o.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pol J Radiol"],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>To study the spectrum of imaging findings in hepatic alveolar echinococcosis (HAE) and to evaluate the potential role of diffusion-weighted imaging (DWI) in its characterisation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>Two radiologists with more than seven years of experience retrospectively studied ultrasonography, computed tomography (CT), and magnetic resonance imaging (MRI) findings in 23 histopathologically proven cases of HAE with emphasis on the appearance and extent of disease. DWI characteristics of lesions were noted, and their apparent diffusion values (ADC) were calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ultrasonography features of HAE included heterogeneous, hyperechoic hepatic mass with or without calcification (n = 20), or heterogeneous mass with solid-cystic appearance (n = 2). CT revealed heterogeneous density infiltrative hepatic mass with no contrast enhancement in 19 patients or thick-walled cystic mass (n = 4). Following Kodama classification one type 1, six type 2, two type 3, eight type 4, and two type 5 lesions were identified on T2-weighted MRI. No enhancement was seen on post-contrast T1-weighted images. Mean ADC values were \n1.74 \u00b1 0.48 \u00d7 10-3 mm2\/s (range: 1.39 \u00d7 10-3 mm2\/s to 2.3 \u00d7 10-3 mm2\/s).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>HAE by virtue of its infiltrative growth pattern with a tendency to involve biliary, vascular, and extra hepatic structures can be easily misdiagnosed as malignant hepatic neoplasm. Knowledge of varied imaging appearances of HAE is essential to suspect the condition and to make an appropriate diagnosis. Diffusion-weighted imaging is a useful adjunct with relatively high diffusivity (high ADC values) suggesting diagnosis of alveolar hydatid.<\/jats:p><\/jats:sec>","DOI":"10.5114\/pjr.2020.101015","type":"journal-article","created":{"date-parts":[[2021,1,4]],"date-time":"2021-01-04T20:35:56Z","timestamp":1609792556000},"page":"613-623","source":"Crossref","is-referenced-by-count":17,"title":["The spectrum of multimodality imaging findings in hepatic alveolar echinococcosis and the potential role of diffusion-weighted imaging \nin its characterisation"],"prefix":"10.5114","volume":"85","author":[{"given":"Arshed H.","family":"Parry","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdul H.","family":"Wani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Imza","family":"Feroz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3061","published-online":{"date-parts":[[2020,11,10]]},"reference":[{"key":"ref-1142842","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1016\/S0140-6736(03)14573-4","article-title":"Echinococcosis","volume":"362","author":"McManus DP","year":"2003","unstructured":"McManus DP, Zhang W, Li J, Bartley PB. 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In: Eckert J, Gemmell MA, Meslin FX, Pawlowski ZS (eds.). WHO\/OIE manual on echinococcosis in humans and animals: a public health problem of global concern. Paris, France: WHO\/OIE; 2001, pp. 20-72."},{"key":"ref-1142847","doi-asserted-by":"crossref","first-page":"247","DOI":"10.5152\/dir.2015.15456","article-title":"Multimodality imaging in diagnosis and management of alveolar echinococcosis: an update","volume":"22","author":"Bulak\u00e7\u0131 M","year":"2016","unstructured":"Bulak\u00e7\u0131 M, Kartal MG, Y\u0131lmaz S, et al. Multimodality imaging in diagnosis and management of alveolar echinococcosis: an update. Diagn Interv Radiol 2016; 22: 247-256.","journal-title":"Diagn Interv Radiol"},{"key":"ref-1142848","first-page":"638375","article-title":"Disseminated alveolar hydatid disease resembling a metastatic malignancy: a diagnostic challenge\u2013a report of two cases","volume":"2014","author":"Bulakci M","year":"2014","unstructured":"Bulakci M, Yilmaz E, Cengel F, et al. 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