{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:34:58Z","timestamp":1762508098115},"reference-count":21,"publisher":"Termedia Sp. z.o.o.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pol J Radiol"],"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>Pulmonary tuberculosis (PTB) is one of the major health problems in the elderly population, causing significant morbidity and mortality. The aim of this study is to evaluate the significance of the high-resolution computed tomography (HRCT) modality for the diagnosis of PTB, in comparison to culture test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>Thoracic HRCT images of the study population, comprising 124 patients clinically suspected for PTB with smear and culture reports, were analysed for sensitivity and specificity of the HRCT test. Features of active PTB were centrilobular nodules, \u2018tree-in-bud\u2019 pattern densities, macro-nodules, consolidations, cavitary lesions, ground-glass opacities, and miliary nodules.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the study population, 108 cases presented HRCT features of active PTB and the remaining cases were negative but had presented a\u00a0few features mimicking PTB. As inferred from positive culture test results, 106 cases had active PTB, the remaining cases were culture negative for PTB. False-positive (FP) or \u2018type I\u00a0error\u2019 cases, and false-negative (FN) or \u2018type II error\u2019 cases were ascertained by Bayes\u2019 theorem. Sensitivity (true positive rate) and specificity (true negative rate) of HRCT test were 0.8125 and 0.8571, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>For proper diagnosis the predictive capability, as two values of \u2018a\u00a0posteriori probability\u2019, was computed; the mean value of \u2018a\u00a0posteriori probability\u2019 for HRCT was 0.6358. When its culture test was positive, the HRCT test was 69.56-92.85% efficient in ascertaining positive results with a\u00a0sample; on the other hand, when its culture test was negative it was 66.66-100% efficient for a\u00a0negative result. Thus, the HRCT test is considerably dependable.<\/jats:p><\/jats:sec>","DOI":"10.5114\/pjr.2020.93697","type":"journal-article","created":{"date-parts":[[2020,4,20]],"date-time":"2020-04-20T21:46:26Z","timestamp":1587419186000},"page":"125-131","source":"Crossref","is-referenced-by-count":4,"title":["Radiological significance of high-resolution computed tomography for elderly pulmonary tuberculosis patients \u2013 an analysis with culture test"],"prefix":"10.5114","volume":"85","author":[{"given":"Niranjan","family":"Sahu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Somadatta","family":"Das","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rabindra Nath","family":"Padhy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3061","published-online":{"date-parts":[[2020,3,6]]},"reference":[{"key":"ref-1145776","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.2169\/internalmedicine.50.5198","article-title":"Relationship between computed tomography findings and nutritional status in elderly patients with pulmonary tuberculosis","volume":"50","author":"Okamura K","year":"2011","unstructured":"Okamura K, Nagata N, Kumazoe H, et al. (2011). Relationship between computed tomography findings and nutritional status in elderly patients with pulmonary tuberculosis. Intern Med. 50: 1809-1814.","journal-title":"Intern Med"},{"key":"ref-1145777","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1159\/000101438","article-title":"Transitional change in the clinical features of pulmonary tuberculosis","volume":"75","author":"Kobashi Y","year":"2008","unstructured":"Kobashi Y, Mouri K, Fukuda M, et al. (2008). Transitional change in the clinical features of pulmonary tuberculosis. Respiration. 75: 304-309.","journal-title":"Respiration"},{"key":"ref-1145778","first-page":"84","article-title":"Clinico-radiological profile of new smear positive pulmonary tuberculosis cases among young adult and elderly people in a tertiary care hospital at Deheradun (Uttarakhand)","volume":"55","author":"Rawat J","year":"2008","unstructured":"Rawat J, Sindhwani G, Juyal R. (2008). Clinico-radiological profile of new smear positive pulmonary tuberculosis cases among young adult and elderly people in a tertiary care hospital at Deheradun (Uttarakhand). Indian J Tuberc. 55: 84-90.","journal-title":"Indian J Tuberc"},{"key":"ref-1145779","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.bjorl.2016.10.010","article-title":"Bayesian analysis of high-resolution ultrasonography and guided FNAC in diagnosis of palpable thyroid nodules","volume":"84","author":"Sahu N","year":"2016","unstructured":"Sahu N, Padhy RN. (2016). Bayesian analysis of high-resolution ultrasonography and guided FNAC in diagnosis of palpable thyroid nodules. Brazilian J Otorhinolaryngol. 84: 20-27.","journal-title":"Brazilian J Otorhinolaryngol"},{"key":"ref-1145780","volume-title":"Fundamentals of biostatistics","author":"Rosner B","year":"2000","unstructured":"Rosner B. (2000). Fundamentals of biostatistics, 5th ed.  Duxbury, Pacific Grove, CA.","edition":"5th ed"},{"key":"ref-1145781","first-page":"286","article-title":"The relationship between malnutrition and tuberculosis: evidence from studies in humans and experimental animals","volume":"8","author":"Cegielski JP","year":"2004","unstructured":"Cegielski JP, McMurray DN. (2004). The relationship between malnutrition and tuberculosis: evidence from studies in humans and experimental animals. Int J Tuberc Lung Dis. 8: 286-298.","journal-title":"Int J Tuberc Lung Dis"},{"key":"ref-1145782","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1080\/028418502127347637","article-title":"Correlation of immunologic status with high resolution CT and distributions of pulmonary tuberculosis","volume":"43","author":"Yabuuchi H","year":"2002","unstructured":"Yabuuchi H, Murayama S, Murakami J, et al. (2002). Correlation of immunologic status with high resolution CT and distributions of pulmonary tuberculosis. Acta Radiologica. 43: 44-47.","journal-title":"Acta Radiologica"},{"key":"ref-1145783","first-page":"611","article-title":"The relation between nutritional state of tuberculous patients admitted in tuberculous ward and their outcome at the time of discharge","volume":"84","author":"Nagata N","year":"2009","unstructured":"Nagata N, Matsunaga K, Wakamatsu K, et al. (2009). The relation between nutritional state of tuberculous patients admitted in tuberculous ward and their outcome at the time of discharge. Kekkaku. 84: 611-616.","journal-title":"Kekkaku"},{"key":"ref-1145784","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1007\/s003910070034","article-title":"Tuberculosis in the elderly","volume":"33","author":"Rajagopalan S","year":"2000","unstructured":"Rajagopalan S, Yoshikawa TT. (2000). Tuberculosis in the elderly. Z Gerontol Geriatr. 33: 374-380.","journal-title":"Z Gerontol Geriatr"},{"key":"ref-1145785","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1111\/j.1532-5415.2006.00850.x","article-title":"Prevalence of tuberculous infection and active tuberculosis in old age homes in Hong Kong","volume":"54","author":"Chan-Yeung M","year":"2006","unstructured":"Chan-Yeung M, Chan F, Cheung A, et al. (2006). Prevalence of tuberculous infection and active tuberculosis in old age homes in Hong Kong. J Am Geriatr Soc. 54: 1334-1340.","journal-title":"J Am Geriatr Soc"},{"key":"ref-1145786","first-page":"21","article-title":"Revised national tuberculosis control programme: Indian perspective","volume":"42","author":"Arora VK","year":"2000","unstructured":"Arora VK, Sarin R. (2000). Revised national tuberculosis control programme: Indian perspective. Indian J Chest Dis Allied Sci. 42: 21-26.","journal-title":"Indian J Chest Dis Allied Sci"},{"key":"ref-1145787","doi-asserted-by":"crossref","first-page":"784","DOI":"10.3346\/jkms.2005.20.5.784","article-title":"Diagnostic and therapeutic problems of pulmonary tuberculosis in elderly patients","volume":"20","author":"Lee JH","year":"2005","unstructured":"Lee JH, Han DH, Song JW, Chung HS. (2005). Diagnostic and therapeutic problems of pulmonary tuberculosis in elderly patients. J Korean Med Sci. 20: 784-789.","journal-title":"J Korean Med Sci"},{"key":"ref-1145788","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1007\/s15010-008-7199-8","article-title":"The impact of age on the demographic, clinical, radiographic characteristics and treatment outcomes of pulmonary tuberculosis patients in Taiwan","volume":"36","author":"Wang CS","year":"2008","unstructured":"Wang CS, Chen HC, Yang CJ, et al. (2008). The impact of age on the demographic, clinical, radiographic characteristics and treatment outcomes of pulmonary tuberculosis patients in Taiwan. Infection. 36: 335-340.","journal-title":"Infection"},{"key":"ref-1145789","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1590\/S1806-37132007000600014","article-title":"Clinical aspects of pulmonary tuberculosis in elderly patients from a university hospital in Rio de Janeiro, Brazil","volume":"33","author":"Cantalice Filho JP","year":"2007","unstructured":"Cantalice Filho JP, Sant Anna CC, B\u00f3ia MN. (2007). Clinical aspects of pulmonary tuberculosis in elderly patients from a university hospital in Rio de Janeiro, Brazil. J Bras Pneumol. 33: 699-706.","journal-title":"J Bras Pneumol"},{"key":"ref-1145790","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1186\/1471-2334-13-121","article-title":"Clinical characteristics and treatment outcomes of tuberculosis in the elderly: a case control study","volume":"13","author":"Kwon YS","year":"2013","unstructured":"Kwon YS, Chi SY, Oh IJ, et al. (2013). Clinical characteristics and treatment outcomes of tuberculosis in the elderly: a case control study. BMC Infect Dis. 13: 121.","journal-title":"BMC Infect Dis"},{"key":"ref-1145791","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1164\/ajrccm.162.5.2001040","article-title":"Progressive age-related changes in pulmonary tuberculosis images and the effect of diabetes","volume":"62","author":"Perez-Guzman C","year":"2000","unstructured":"Perez-Guzman C, Torres-Cruz A, Villarreal-velarde H, Vargas MH. (2000). Progressive age-related changes in pulmonary tuberculosis images and the effect of diabetes. Am J Respir Crit Care Med. 62: 1738-1740.","journal-title":"Am J Respir Crit Care Med"},{"key":"ref-1145792","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/j.athoracsur.2004.09.007","article-title":"Current surgical intervention for pulmonary tuberculosis","volume":"79","author":"Takeda S","year":"2005","unstructured":"Takeda S, Maeda H, Hayakawa M, et al. (2005). Current surgical intervention for pulmonary tuberculosis. Ann Thorac Surg. 79: 959-963.","journal-title":"Ann Thorac Surg"},{"key":"ref-1145793","first-page":"156","article-title":"The problem of geriatric tuberculosis","volume":"5","author":"Sood R","year":"2000","unstructured":"Sood R. (2000). The problem of geriatric tuberculosis. J Indian Acad Clin Med. 5: 156-162.","journal-title":"J Indian Acad Clin Med"},{"key":"ref-1145794","first-page":"83","article-title":"Tuberculosis in the elderly and their treatment outcome under DOTS","volume":"51","author":"Gaur SN","year":"2004","unstructured":"Gaur SN, Dhingra VK, Rajpal S, et al. (2004). Tuberculosis in the elderly and their treatment outcome under DOTS. Indian J Tuberc. 51: 83-87.","journal-title":"Indian J Tuberc"},{"key":"ref-1145795","first-page":"1157","article-title":"TB in the elderly in industrialised countries","volume":"11","author":"Davies PD","year":"2007","unstructured":"Davies PD. (2007). TB in the elderly in industrialised countries. Int J Tuberc Lung Dis. 11: 1157-1159.","journal-title":"Int J Tuberc Lung Dis"},{"key":"ref-1145796","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1159\/000052794","article-title":"Tuberculosis in the elderly","volume":"47","author":"Packham S","year":"2001","unstructured":"Packham S. (2001). Tuberculosis in the elderly. Gerontology. 47: 175-179.","journal-title":"Gerontology"}],"container-title":["Polish Journal of Radiology"],"original-title":[],"link":[{"URL":"https:\/\/www.polradiol.com\/pdf-118071-108862","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.polradiol.com\/pdf-118071-108862","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T11:19:47Z","timestamp":1716376787000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.polradiol.com\/Radiological-significance-of-high-resolution-computed-tomography-for-elderly-pulmonary,118071,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,6]]},"references-count":21,"alternative-id":["118071"],"URL":"https:\/\/doi.org\/10.5114\/pjr.2020.93697","relation":{},"ISSN":["1899-0967"],"issn-type":[{"value":"1899-0967","type":"print"}],"subject":[],"published":{"date-parts":[[2020,3,6]]}}}