{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T15:24:07Z","timestamp":1790090647528,"version":"4.0.1"},"reference-count":27,"publisher":"Termedia Sp. z.o.o.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pol J Radiol"],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>The diagnosis of Crohn\u2019s disease (CD), one of the inflammatory bowel diseases (IBD), along with ulcera\u00adtive colitis (UC), is often challenging due to the limitations of small intestine visualisation. Magnetic resonance enterography (MRE) enables imaging of intraluminal and extraintestinal complications without ionizing radiation. The objective of this study is to select CD-related MRE features and determine the feasibility of this technique to indicate a\u00a0group of patients that should be subjected to more invasive diagnostic procedures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>A\u00a0total of 131 patients (mean age 25) underwent MRE, 60 of whom had been previously diagnosed with CD and 17 with UC. Additionally, 26 patients with suspected IBD and 28 with other or unknown patholo\u00adgies were included in the study. Radiological reports of MRE examinations, effectuated using a\u00a01.5-T field strength, were retrospectively analysed regarding radiological features of IBD, such as the following: bowel wall thickening, enhancement, comb sign, stricture, enlarged mesenteric nodes, inflammatory infiltration, and abnormal diffusion restriction in diffusion-weighted imaging. The statistical model was based on machine learning of the Kohonen map, together with univariate and multivariate analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The selected neuron (Neuron 3) incorporated 23 cases of CD, 9 of suspected IBD, 2 patients with UC, and 4 with other pathologies. The statistical analysis identified bowel wall thickening, intestinal stricture, and lymphadenopathy as the 3 MRE findings most associated with Neuron 3 (AUC = 0.919, p = 0.031).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Bowel wall thickening, stricture, and enlarged mesenteric lymph nodes in MRE are independent predictive factors for CD diagnosis; thus, patients presenting these features should undergo further examinations. MRE constitutes a\u00a0powerful imaging modality in cases of suspected IBD.<\/jats:p><\/jats:sec>","DOI":"10.5114\/pjr.2021.104581","type":"journal-article","created":{"date-parts":[[2021,4,27]],"date-time":"2021-04-27T20:02:41Z","timestamp":1619553761000},"page":"143-150","source":"Crossref","is-referenced-by-count":4,"title":["The value of magnetic resonance enterography in diagnostic difficulties associated with Crohn\u2019s disease"],"prefix":"10.5114","volume":"86","author":[{"given":"Katarzyna B.","family":"Biernacka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dobromi\u0142a","family":"Bara\u0144ska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarzyna","family":"Matera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Micha\u0142","family":"Podg\u00f3rski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"El\u017cbieta","family":"Czkwianianc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarzyna","family":"Szabelska-Zakrzewska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inga","family":"Dziembowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr","family":"Grzelak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3061","published-online":{"date-parts":[[2021,3,3]]},"reference":[{"key":"ref-1150260","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1093\/ibd\/izz004","article-title":"Microbiota-nourishing immunity and its relevance for ulcerative colitis","volume":"25","author":"Byndloss MX","year":"2019","unstructured":"Byndloss MX, Litvak Y, B\u00e4umler AJ. 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