{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T03:19:49Z","timestamp":1764645589320},"reference-count":42,"publisher":"Termedia Sp. z.o.o.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pol J Radiol"],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>To assess the prevalence of the neuroradiological indices of cerebral small vessel disease (CSVD) in patients with severe aortic valve stenosis (AS) in magnetic resonance imaging (MRI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>34 patients (age 60-90 years, 17 women and 17 men) with severe AS and 50 healthy controls (age 61-85 years, 29 women and 21 men) underwent MRI brain examinations, which were analysed for the neuroradiological indices of CSVD: hyperintensities in periventricular white matter (PVWM) and deep white matter (DWM), enlarged perivascular spaces (ePVS), lacunar strokes, and cerebral microbleeds (CMBs).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>PVWM hyperintensities were found in 46% of volunteers and was significantly lower (p = 0.027), corresponding to AS patients (80%), the density of lesions was higher in the AS group than in controls (p = 0.019). DWM hyperintensities were found more often in AS patients (76%) than in controls (66%) (p = 0.303), but the densities were similar in both groups. Lacunar strokes were found in 35% of AS patients and 16% of controls (p = 0.042). The average number of lacunar strokes per person was 0.9 in the AS group and 0.3 in the controls (p = 0.035). The AS group showed higher variance in the number of strokes: SD = 1.96 vs. SD = 1.06 in controls. Both prevalence and density of the ePVS and CMBs did not differ significantly between the groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Neuroradiological indices of the vascular disease do not provide an unequivocal clue to the pathogenesis of CSVD in patients with severe AS. Most observations imply that CSVD is primarily a\u00a0consequence of cerebral hypoperfusion caused by AS.<\/jats:p><\/jats:sec>","DOI":"10.5114\/pjr.2021.110650","type":"journal-article","created":{"date-parts":[[2021,12,16]],"date-time":"2021-12-16T12:27:57Z","timestamp":1639657677000},"page":"564-573","source":"Crossref","is-referenced-by-count":1,"title":["Magnetic resonance imaging assessment of cerebral small vessel disease intensification in patients with severe aortic valve stenosis"],"prefix":"10.5114","volume":"86","author":[{"given":"Jakub","family":"Chrostowski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcin","family":"Majos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrzej","family":"Walczak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariusz","family":"Wachowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agata","family":"Majos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3061","published-online":{"date-parts":[[2021,9,27]]},"reference":[{"key":"ref-1147361","article-title":"Trwanie \u017cycia w 2018 r. [Life expectancy in 2018] stat.gov.pl","author":"GUS","unstructured":"GUS. Trwanie \u017cycia w 2018 r. [Life expectancy in 2018] stat.gov.pl. https:\/\/stat.gov.pl\/obszary-tematyczne\/ludnosc\/trwanie-zycia\/trwanie-zycia-w-2018-r-,2,13.html. Published: 2019."},{"key":"ref-1147362","doi-asserted-by":"crossref","first-page":"e139","DOI":"10.1161\/CIR.0000000000000757","article-title":"Heart disease and stroke statistics\u20132020 update: a report from the American Heart Association","volume":"141","author":"Virani SS","year":"2020","unstructured":"Virani SS, Alonso A, Benjamin EJ, et al. Heart disease and stroke statistics\u20132020 update: a report from the American Heart Association. Circulation 2020; 141: e139-e596.","journal-title":"Circulation"},{"key":"ref-1147363","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.echo.2017.02.009","article-title":"Recommendations on the echocardiographic assessment of aortic valve stenosis: a focused update from the European Association of Cardiovascular Imaging and the American Society of Echocardiography","volume":"30","author":"Baumgartner H","year":"2017","unstructured":"Baumgartner H, Hung J, Bermejo J, et al. Recommendations on the echocardiographic assessment of aortic valve stenosis: a focused update from the European Association of Cardiovascular Imaging and the American Society of Echocardiography. J Am Soc Echocardiogr 2017; 30: 372-392.","journal-title":"J Am Soc Echocardiogr"},{"key":"ref-1147364","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1016\/S0140-6736(09)60211-7","article-title":"Aortic stenosis","volume":"373","author":"Carabello BA","year":"2009","unstructured":"Carabello BA, Paulus WJ. Aortic stenosis. Lancet 2009; 373: 956-966.","journal-title":"Lancet"},{"key":"ref-1147365","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/S1474-4422(10)70104-6","article-title":"Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges","volume":"9","author":"Pantoni L","year":"2010","unstructured":"Pantoni L. Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges. Lancet Neurol 2010; 9: 689-701.","journal-title":"Lancet Neurol"},{"key":"ref-1147366","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/S1474-4422(13)70124-8","article-title":"Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration","volume":"12","author":"Wardlaw JM","year":"2013","unstructured":"Wardlaw JM, Smith EE, Biessels GJ, et al. Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration. Lancet Neurol 2013; 12: 822-838.","journal-title":"Lancet Neurol"},{"key":"ref-1147367","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1212\/WNL.0000000000007654","article-title":"CNS small vessel disease: a clinical review","volume":"92","author":"Cannistraro RJ","year":"2019","unstructured":"Cannistraro RJ, Badi M, Eidelman BH, et al. CNS small vessel disease: a clinical review. Neurology 2019; 92: 1146-1156.","journal-title":"Neurology"},{"key":"ref-1147368","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1161\/01.STR.31.2.425","article-title":"Aortic atherosclerosis at middle age predicts cerebral white matter lesions in the elderly","volume":"31","author":"de Leeuw FE","year":"2000","unstructured":"de Leeuw FE, De Groot JC, Oudkerk M, et al. Aortic atherosclerosis at middle age predicts cerebral white matter lesions in the elderly. Stroke 2000; 31: 425-429.","journal-title":"Stroke"},{"key":"ref-1147369","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1002\/gps.1283","article-title":"White matter lesions on magnetic resonance imaging and their relationship with vascular risk factors in memory clinic attenders","volume":"20","author":"Lazarus R","year":"2005","unstructured":"Lazarus R, Prettyman R, Cherryman G. White matter lesions on magnetic resonance imaging and their relationship with vascular risk factors in memory clinic attenders. Int J Geriatr Psychiatry 2005; 20: 274-279.","journal-title":"Int J Geriatr Psychiatry"},{"key":"ref-1147370","doi-asserted-by":"crossref","first-page":"351","DOI":"10.2214\/ajr.149.2.351","article-title":"MR signal abnormalities at 1.5 Tin Alzheimer\u2019s dementia and normal aging","volume":"149","author":"Fazekas F","year":"1987","unstructured":"Fazekas F, Chawluk JB, Alavi A, et al. MR signal abnormalities at 1.5 Tin Alzheimer\u2019s dementia and normal aging. AJR Am J Roentgenol 1987; 149: 351-356.","journal-title":"AJR Am J Roentgenol"},{"key":"ref-1147371","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1136\/jnnp.2003.030858","article-title":"Enlarged perivascular spaces are associated with cognitive function in healthy elderly men","volume":"75","author":"Maclullich AM","year":"2004","unstructured":"Maclullich AM, Wardlaw JM, Ferguson KJ, et al. Enlarged perivascular spaces are associated with cognitive function in healthy elderly men. J Neurol Neurosurg Psychiatry 2004; 75: 1519-1523.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref-1147372","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1212\/WNL.0b013e3181c34a7d","article-title":"The Microbleed Anatomical Rating Scale (MARS): reliability of a tool to map brain microbleeds","volume":"73","author":"Gregoire SM","year":"2009","unstructured":"Gregoire SM, Chaudhary UJ, Brown MM, et al. The Microbleed Anatomical Rating Scale (MARS): reliability of a tool to map brain microbleeds. Neurology 2009; 73: 1759-1766.","journal-title":"Neurology"},{"key":"ref-1147373","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1002\/gps.1283","article-title":"White matter lesions on magnetic resonance imaging and their relationship with vascular risk factors in memory clinic attenders","volume":"20","author":"Lazarus R","year":"2005","unstructured":"Lazarus R, Prettyman R, Cherryman G. White matter lesions on magnetic resonance imaging and their relationship with vascular risk factors in memory clinic attenders. Int J Geriatr Psychiatry 2005; 20: 274-279.","journal-title":"Int J Geriatr Psychiatry"},{"key":"ref-1147374","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1007\/s004150050586","article-title":"Carotid atherosclerosis and cerebral white matter lesions in a population based magnetic resonance imaging study","volume":"247","author":"de Leeuw FE","year":"2000","unstructured":"de Leeuw FE, de Groot JC, Bots ML, et al. Carotid atherosclerosis and cerebral white matter lesions in a population based magnetic resonance imaging study. J Neurol 2000; 247: 291-296.","journal-title":"J Neurol"},{"key":"ref-1147375","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1046\/j.1532-5415.2001.49126.x","article-title":"Serum carotenoids and cerebral white matter lesions: the Rotterdam scan study","volume":"49","author":"den Heijer T","year":"2001","unstructured":"den Heijer T, Launer LJ, de Groot JC, et al. Serum carotenoids and cerebral white matter lesions: the Rotterdam scan study. J Am Geriatr Soc 2001; 49: 642-646.","journal-title":"J Am Geriatr Soc"},{"key":"ref-1147376","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1136\/jnnp.2006.103549","article-title":"Risk factor profile of cerebral small vessel disease and its subtypes","volume":"78","author":"Khan U","year":"2007","unstructured":"Khan U, Porteous L, Hassan A, Markus HS. Risk factor profile of cerebral small vessel disease and its subtypes. J Neurol Neurosurg Psychiatry 2007; 78: 702-706.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref-1147377","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.biopsych.2008.03.024","article-title":"Classification of white matter lesions on magnetic resonance imaging in elderly persons","volume":"64","author":"Kim KW","year":"2008","unstructured":"Kim KW, MacFall JR, Payne ME. Classification of white matter lesions on magnetic resonance imaging in elderly persons. Biol Psychiatry 2008; 64: 273-280.","journal-title":"Biol Psychiatry"},{"key":"ref-1147378","doi-asserted-by":"crossref","first-page":"144","DOI":"10.5853\/jos.2015.17.2.144","article-title":"A functional perspective on the embryology and anatomy of the cerebral blood supply","volume":"17","author":"Menshawi K","year":"2015","unstructured":"Menshawi K, Mohr JP, Gutierrez J. A functional perspective on the embryology and anatomy of the cerebral blood supply. J Stroke 2015; 17: 144-158.","journal-title":"J Stroke"},{"key":"ref-1147379","first-page":"431","article-title":"Features of the cerebral vascular pattern that predict vulnerability to perfusion or oxygenation deficiency: an anatomic study","volume":"11","author":"Moody DM","year":"1990","unstructured":"Moody DM, Bell MA, Challa VR. Features of the cerebral vascular pattern that predict vulnerability to perfusion or oxygenation deficiency: an anatomic study. AJNR Am J Neuroradiol 1990; 11: 431-439.","journal-title":"AJNR Am J Neuroradiol"},{"key":"ref-1147380","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1161\/01.STR.27.9.1641","article-title":"Cerebral white matter is highly vulnerable to ischemia","volume":"27","author":"Pantoni L","year":"1996","unstructured":"Pantoni L, Garcia JH, Gutierrez JA. Cerebral white matter is highly vulnerable to ischemia. Stroke 1996; 27: 1641-1647.","journal-title":"Stroke"},{"key":"ref-1147381","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/S1474-4422(07)70170-9","article-title":"Silent brain infarcts: a systematic review","volume":"6","author":"Vermeer SE","year":"2007","unstructured":"Vermeer SE, Longstreth WT, Koudstaal PJ. Silent brain infarcts: a systematic review. Lancet Neurol 2007; 6: 611-619.","journal-title":"Lancet Neurol"},{"key":"ref-1147382","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1001\/jamaneurol.2018.1073","article-title":"Advances in understanding the pathophysiology of lacunar stroke: a review","volume":"75","author":"Regenhardt RW","year":"2018","unstructured":"Regenhardt RW, Das AS, Lo EH, Caplan LR. Advances in understanding the pathophysiology of lacunar stroke: a review. JAMA Neurol 2018; 75: 1273-1281.","journal-title":"JAMA Neurol"},{"key":"ref-1147383","doi-asserted-by":"crossref","first-page":"2","DOI":"10.5853\/jos.2015.17.1.2","article-title":"Lacunar infarction and small vessel disease: pathology and pathophysiology","volume":"17","author":"Caplan LR","year":"2015","unstructured":"Caplan LR. Lacunar infarction and small vessel disease: pathology and pathophysiology. J Stroke 2015; 17: 2-6.","journal-title":"J Stroke"},{"key":"ref-1147384","first-page":"220","article-title":"Examining subcortical infarcts in the era of acute multimodality CT imaging","volume":"7","author":"Tan MY","year":"2016","unstructured":"Tan MY, Singhal S, Ma H, et al. Examining subcortical infarcts in the era of acute multimodality CT imaging. Front Neurol 2016; 7: 220.","journal-title":"Front Neurol"},{"key":"ref-1147385","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1111\/ggi.12599","article-title":"Calcifications in the carotid siphon correlate with silent cerebral small vessel disease in community-dwelling older adults: a population-based study in rural Ecuador","volume":"16","author":"Del Brutto OH","year":"2016","unstructured":"Del Brutto OH, Mera RM, Gillman J, et al. Calcifications in the carotid siphon correlate with silent cerebral small vessel disease in community-dwelling older adults: a population-based study in rural Ecuador. Geriatr Gerontol Int 2016; 16: 1063-1067.","journal-title":"Geriatr Gerontol Int"},{"key":"ref-1147386","doi-asserted-by":"crossref","first-page":"312","DOI":"10.5853\/jos.2016.00171","article-title":"Association between aortic atheroma and cerebral small vessel disease in patients with ischemic stroke","volume":"18","author":"Song TJ","year":"2016","unstructured":"Song TJ, Kim YD, Yoo J, et al. Association between aortic atheroma and cerebral small vessel disease in patients with ischemic stroke. J Stroke 2016; 18: 312-320.","journal-title":"J Stroke"},{"key":"ref-1147387","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1007\/s00415-008-0777-y","article-title":"Virchow-Robin spaces relate to cerebral small vessel disease severity","volume":"255","author":"Rouhl RP","year":"2008","unstructured":"Rouhl RP, van Oostenbrugge RJ, Knottnerus IL, et al. Virchow-Robin spaces relate to cerebral small vessel disease severity. J Neurol 2008; 255: 692-696.","journal-title":"J Neurol"},{"key":"ref-1147388","doi-asserted-by":"crossref","first-page":"2116","DOI":"10.1212\/WNL.0000000000001054","article-title":"Topography and associations of perivascular spaces in healthy adults: the Kashima scan study","volume":"83","author":"Yakushiji Y","year":"2014","unstructured":"Yakushiji Y, Charidimou A, Hara M, et al. Topography and associations of perivascular spaces in healthy adults: the Kashima scan study. Neurology 2014; 83: 2116-2123.","journal-title":"Neurology"},{"key":"ref-1147389","doi-asserted-by":"crossref","first-page":"709","DOI":"10.3174\/ajnr.A2366","article-title":"Frequency and location of dilated Virchow-Robin spaces in elderly people: a population-based 3D MR imaging study","volume":"32","author":"Zhu YC","year":"2011","unstructured":"Zhu YC, Dufouil C, Mazoyer B, et al. Frequency and location of dilated Virchow-Robin spaces in elderly people: a population-based 3D MR imaging study. AJNR Am J Neuroradiol 2011; 32: 709-713.","journal-title":"AJNR Am J Neuroradiol"},{"key":"ref-1147390","doi-asserted-by":"crossref","first-page":"2483","DOI":"10.1161\/STROKEAHA.110.591586","article-title":"Severity of dilated Virchow-Robin spaces is associated with age, blood pressure, and MRI markers of small vessel disease: a population-based study","volume":"41","author":"Zhu YC","year":"2010","unstructured":"Zhu YC, Tzourio C, Soumar\u00e9 A, et al. Severity of dilated Virchow-Robin spaces is associated with age, blood pressure, and MRI markers of small vessel disease: a population-based study. Stroke 2010; 41: 2483-2490.","journal-title":"Stroke"},{"key":"ref-1147391","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1159\/000375153","article-title":"Cerebral perivascular spaces visible on magnetic resonance imaging: development of a qualitative rating scale and its observer reliability","volume":"39","author":"Potter GM","year":"2015","unstructured":"Potter GM, Chappell FM, Morris Z, Wardlaw JM. Cerebral perivascular spaces visible on magnetic resonance imaging: development of a qualitative rating scale and its observer reliability. Cerebrovasc Dis 2015; 39: 224-231.","journal-title":"Cerebrovasc Dis"},{"key":"ref-1147392","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1111\/nan.12062","article-title":"Brain haemosiderin in older people: pathological evidence for an ischaemic origin of magnetic resonance imaging (MRI) microbleeds","volume":"40","author":"Janaway BM","year":"2014","unstructured":"Janaway BM, Simpson JE, Hoggard N, et al. Brain haemosiderin in older people: pathological evidence for an ischaemic origin of magnetic resonance imaging (MRI) microbleeds. Neuropathol Appl Neurobiol 2014; 40: 258-269.","journal-title":"Neuropathol Appl Neurobiol"},{"key":"ref-1147393","doi-asserted-by":"publisher","DOI":"10.1111\/1754-9485.12726"},{"key":"ref-1147394","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1136\/jnnp.2007.121913","article-title":"Cerebral microbleeds in the population based AGES-Reykjavik study: prevalence and location","volume":"79","author":"Sveinbjornsdottir S","year":"2008","unstructured":"Sveinbjornsdottir S, Sigurdsson S, Aspelund T, et al. Cerebral microbleeds in the population based AGES-Reykjavik study: prevalence and location. J Neurol Neurosurg Psychiatry 2008; 79: 1002-1006.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref-1147395","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1212\/01.wnl.0000307750.41970.d9","article-title":"Prevalence and risk factors of cerebral microbleeds: the Rotterdam Scan Study","volume":"70","author":"Vernooij MW","year":"2008","unstructured":"Vernooij MW, van der Lugt A, Ikram MA, et al. Prevalence and risk factors of cerebral microbleeds: the Rotterdam Scan Study. Neurology 2008; 70: 1208-1214.","journal-title":"Neurology"},{"key":"ref-1147396","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S1474-4422(09)70013-4","article-title":"Cerebral microbleeds: a guide to detection and interpretation","volume":"8","author":"Greenberg SM","year":"2009","unstructured":"Greenberg SM, Vernooij MW, Cordonnier C, et al. Cerebral microbleeds: a guide to detection and interpretation. Lancet Neurol 2009; 8: 165-174.","journal-title":"Lancet Neurol"},{"key":"ref-1147397","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.1161\/STROKEAHA.114.004130","article-title":"Risk factors, stroke prevention treatments, and prevalence of cerebral microbleeds in the Framingham Heart Study","volume":"45","author":"Romero JR","year":"2014","unstructured":"Romero JR, Preis SR, Beiser A, et al. Risk factors, stroke prevention treatments, and prevalence of cerebral microbleeds in the Framingham Heart Study. Stroke 2014; 45: 1492-1494.","journal-title":"Stroke"},{"key":"ref-1147398","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1212\/WNL.0000000000000285","article-title":"Incidence of cerebral microbleeds in preclinical Alzheimer disease","volume":"82","author":"Yates PA","year":"2014","unstructured":"Yates PA, Desmond PM, Phal PM, et al. Incidence of cerebral microbleeds in preclinical Alzheimer disease. Neurology 2014; 82: 1266-1273.","journal-title":"Neurology"},{"key":"ref-1147399","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1001\/jamaneurol.2015.1359","article-title":"Incidental cerebral microbleeds and cerebral blood flow in elderly individuals","volume":"72","author":"Gregg NM","year":"2015","unstructured":"Gregg NM, Kim AE, Gurol ME, et al. Incidental cerebral microbleeds and cerebral blood flow in elderly individuals. JAMA Neurol 2015; 72: 1021-1028.","journal-title":"JAMA Neurol"},{"key":"ref-1147400","doi-asserted-by":"crossref","first-page":"e002377","DOI":"10.1161\/JAHA.115.002377","article-title":"Carotid Atherosclerosis and Cerebral Microbleeds: The Framingham Heart Study","volume":"5","author":"Romero JR","year":"2016","unstructured":"Romero JR, Preis SR, Beiser A, et al. Carotid Atherosclerosis and Cerebral Microbleeds: The Framingham Heart Study. J Am Heart Assoc 2016; 5: e002377.","journal-title":"J Am Heart Assoc"},{"key":"ref-1147401","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1161\/ATVBAHA.115.305451","article-title":"Carotid arterial stiffness and risk of incident cerebral microbleeds in older people: the Age, Gene\/Environment Susceptibility (AGES)-Reykjavik study","volume":"35","author":"Ding J","year":"2015","unstructured":"Ding J, Mitchell GF, Bots ML, et al. Carotid arterial stiffness and risk of incident cerebral microbleeds in older people: the Age, Gene\/Environment Susceptibility (AGES)-Reykjavik study. Arterioscler Thromb Vasc Biol 2015; 35: 1889-1895.","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"ref-1147402","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1159\/000358513","article-title":"Carotid artery calcification is associated with deep cerebral microbleeds","volume":"72","author":"Chung PW","year":"2014","unstructured":"Chung PW, Park KY, Kim JM, et al. Carotid artery calcification is associated with deep cerebral microbleeds. Eur Neurol 2014; 72: 60-63.","journal-title":"Eur Neurol"}],"container-title":["Polish Journal of Radiology"],"original-title":[],"link":[{"URL":"https:\/\/www.polradiol.com\/pdf-128191-108896","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.polradiol.com\/pdf-128191-108896","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T11:30:49Z","timestamp":1716377449000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.polradiol.com\/Magnetic-resonance-imaging-assessment-of-cerebral-small-vessel-disease-intensification,128191,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,27]]},"references-count":42,"alternative-id":["128191"],"URL":"https:\/\/doi.org\/10.5114\/pjr.2021.110650","relation":{},"ISSN":["1899-0967"],"issn-type":[{"value":"1899-0967","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9,27]]}}}