{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T08:53:00Z","timestamp":1762851180457,"version":"build-2065373602"},"reference-count":42,"publisher":"Termedia Sp. z.o.o.","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Reumatologia"],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Previous research has explored the\u00a0uncertain association between metabolic syndrome (MetS) and bone mineral density (BMD). The\u00a0objective of\u00a0this study was to determine the\u00a0prevalence of\u00a0MetS in postmenopausal Moroccan women with osteoporosis and to examine the\u00a0relationship between MetS, BMD, and bone turnover markers among this sample.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and methods<\/jats:title>\n                    <jats:p>This was a\u00a0cross-sectional study of\u00a0100 postmenopausal women. Anthropometric parameters and biochemical blood tests were assessed. Bone mineral density and T-scores in the\u00a0lumbar spine and femoral neck were screened. Bone mineral density was determined using dual-energy X-ray absorptiometry. National Cholesterol Education Program-Adult Treatment Panel III criteria were used to define MetS. The\u00a0association between the\u00a0MetS components, BMD, and bone turnover markers was evaluated by partial correlation and multiple linear regression ana\u00adlysis using SPSS software.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Prevalence of\u00a0MetS in our patients was 44%. The\u00a0mean age of\u00a0patients with and those without MetS was 63.82 \u00b18.65 and 60.39 \u00b17.93, respectively; p\u00a0=\u00a00.04. Lumbar spine BMD correlated significantly with high-density lipoprotein cholesterol (HDL-C; r\u00a0=\u00a0\u20130.233; p\u00a0=\u00a00.02). Lumbar spine T-score correlated with systolic blood pressure (SBP; r\u00a0=\u00a0\u20130.196; p\u00a0=\u00a00.005) and waist circumference (r\u00a0=\u00a00.274; p\u00a0=\u00a00.006). Femoral neck T-score correlated with diastolic blood pressure (r\u00a0=\u00a0\u20130.218; p\u00a0=\u00a00.02) and waist circumference (r\u00a0=\u00a00.294; p\u00a0=\u00a00.003). Osteocalcin inversely correlated with HDL-C and fasting plasma glucose (r\u00a0=\u00a0\u20130.199; p\u00a0=\u00a00.04 and r\u00a0=\u00a0\u20130.238; p\u00a0=\u00a00.01 respectively). \nCarboxy-terminal cross-linked telopeptide of\u00a0type I collagen correlated negatively with HDL-C and SBP (r\u00a0=\u00a0\u20130.238; p\u00a0=\u00a00.02 and r\u00a0=\u00a0\u20130.243; p\u00a0=\u00a00.01 respectively). After linear regression, lumbar spine BMD was associated with age (\u03b2\u00a0=\u00a0\u20132.120, p\u00a0=\u00a00.04), SBP (\u03b2\u00a0=\u00a0\u20130.112, p\u00a0=\u00a00.01) and waist circumfe\u00adrence (\u03b2\u00a0=\u00a00.253, p\u00a0=\u00a00.001). Femoral neck BMD was associated with age (\u03b2\u00a0=\u00a0\u20130.227, p\u00a0=\u00a00.02) and waist circumference (\u03b2\u00a0=\u00a00.258, p\u00a0=\u00a00.008).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The\u00a0prevalence of\u00a0MetS was associated with osteoporosis in postmenopausal Moroccan women, predominantly driven by age, blood pressure, and central obesity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.5114\/reum\/203545","type":"journal-article","created":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T08:48:01Z","timestamp":1762850881000},"page":"321-330","source":"Crossref","is-referenced-by-count":0,"title":["Metabolic syndrome in postmenopausal women with osteoporosis and its relationship with bone density and turnover markers"],"prefix":"10.5114","volume":"63","author":[{"given":"Bahouq","family":"Hanane","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bahouq","family":"Madiha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soulaymani","family":"Abdelmajid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3061","published-online":{"date-parts":[[2025,11,11]]},"reference":[{"key":"ref-1592262","doi-asserted-by":"publisher","DOI":"10.1007\/s40618-020-01428-w"},{"key":"ref-1592263","doi-asserted-by":"publisher","DOI":"10.23736\/S2724-606X.20.04689-4"},{"key":"ref-1592264","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.2003.18.4.784"},{"key":"ref-1592265","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.192644"},{"key":"ref-1592266","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-007-0385-1"},{"key":"ref-1592267","doi-asserted-by":"publisher","DOI":"10.1007\/s11657-019-0615-0"},{"key":"ref-1592268","doi-asserted-by":"crossref","unstructured":"Kim BJ, Ahn SH, Bae SJ, et al. 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