{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T08:14:43Z","timestamp":1766391283844,"version":"3.48.0"},"reference-count":42,"publisher":"Termedia Sp. z.o.o.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Reumatologia"],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>To evaluate physical activity (PA) levels in patients with psoriatic arthritis (PsA) and their associations with cardiovascular (CV) risk factors, psychosocial parameters, and functional status, and to identify distinct patient subgroups using latent class analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and methods<\/jats:title>\n                    <jats:p>In this cross-sectional study, 62 adults with PsA fulfilling Classification Criteria for Psoriatic Arthritis (CASPAR) were consecutively recruited from the\u00a0Institute of\u00a0Rheumatology. Phy\u00adsical activity was assessed using the\u00a0International Physical Activity Questionnaire Short Form (IPAQ-SF) and categorized as low, moderate, or high. Cardiovascular risk factors, fatigue (Functional Assessment of Chronic Illness Therapy Fatigue Scale \u2013 FACIT-F), functional status (Health Assessment Questionnaire Disability Index \u2013 HAQ-DI), depression (Patient Health Questionnaire-9 \u2013 PHQ-9), an\u00adxiety (Beck Anxiety Inventory \u2013 BAI), kinesiophobia (Tampa Scale for Kinesiophobia \u2013 TSK), and sarcopenia risk (SARC-F) were evaluated. Disease activity was measured using the\u00a0clinical Disease Activity Index for Psoriatic Arthritis (cDAPsA). Latent class analysis was applied to identify patient subgroups based on PA, comorbidities, and psychosocial variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Mean age was 44.5 \u00b110.3 years; 52% were female. Physical activity was low in 19.4%, mode\u00adrate in 67.7%, and high in 12.9%. Lower PA was associated with older age (p = 0.04), higher fatigue (FACIT-F 29 \u00b17 vs. 43 \u00b16.4, p = 0.01), and greater disability (HAQ-DI 0.9 vs. 0.1, p = 0.03). The\u00a0prevalence of\u00a0obesity was 51.6% (n = 32), hypertension (HT) 23% (n = 16), dyslipidemia 30% (n = 19), and diabetes mellitus type 2 12.9% (n = 8). Latent class analysis identified two classes: class I\u00a0\u2013 younger, predominantly female (56%), higher education (82%), moderate PA (75%), lower cardiometabolic burden (obesity 46%, HT 14%, dyslipidemia 10%), and lower psychosocial impact; class II \u2013 broader age range, male predominance (54%), lower PA (30% low, 60% moderate), higher cardiometabolic burden (HT 86%, obesity 56%, dyslipidemia 35%), greater kinesiophobia (74%), and sarcopenia risk (19%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In PsA, low PA is associated with higher fatigue, functional impairment, and cardiometabolic and psychosocial burden. Latent class analysis revealed distinct subgroups, suggesting the\u00a0need for personalized, multidisciplinary interventions targeting physical and psychological barriers. Integrating tailored PA promotion alongside pharmacological control may improve both joint and CV outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.5114\/reum\/211836","type":"journal-article","created":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T08:05:17Z","timestamp":1766390717000},"source":"Crossref","is-referenced-by-count":0,"title":["Physical inactivity and other cardiovascular risk factors in patients with psoriatic arthritis: Do we really \u201ckill two birds with one stone\u201d by managing inflammation?"],"prefix":"10.5114","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6203-237X","authenticated-orcid":true,"given":"Sretko","family":"Lukovic","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7386-8757","authenticated-orcid":false,"given":"Nina","family":"Tomonjic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6930-1539","authenticated-orcid":false,"given":"Marina","family":"Vujovic Sestakov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0631-2924","authenticated-orcid":false,"given":"Jovana","family":"Mihailovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleksandra","family":"Neskovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katarina","family":"Lausevic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maja","family":"Zlatanovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-8194-8200","authenticated-orcid":false,"given":"Branko","family":"Barac","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatjana","family":"Zivanovic Radnic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4035-9515","authenticated-orcid":false,"given":"Predrag","family":"Ostojic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3061","published-online":{"date-parts":[[2025,12,19]]},"reference":[{"key":"ref-1621512","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2004.032482"},{"key":"ref-1621513","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ken090"},{"key":"ref-1621514","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-014-0191-y"},{"key":"ref-1621515","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2014-205675"},{"key":"ref-1621516","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2011-201194"},{"key":"ref-1621517","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-"},{"key":"ref-1621518","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2009.94"},{"key":"ref-1621519","doi-asserted-by":"crossref","unstructured":"Metsios GS, Moe RH, Kitas GD. 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