{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T09:47:45Z","timestamp":1694598465114},"reference-count":0,"publisher":"Termedia Sp. z.o.o.","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Reumatologia"],"published-print":{"date-parts":[[2015,7,30]]},"abstract":"<jats:p>A case report of a boy with juvenile idiopathic arthritis since the age of 2 years, generalized onset, complicated by nephrotic syndrome due to secondary type A amyloidosis is presented.&lt;br \/&gt;\nIn the patient the disease had an especially severe course, complicated by frequent infections, making routine treatment difficult. Amyloidosis was diagnosed in the 5th year of the disease based on a rectal biopsy. Since the disease onset the boy has been taking prednisolone and sequentially cyclosporine A, methotrexate, chlorambucil, etanercept, and cyclophosphamide. Clinical and laboratory remission was observed after treatment with tocilizumab. After 42 months of treatment with tocilizumab the boy\u2019s condition is good. There is no pain or joint edema, and no signs of nephrotic syndrome.<\/jats:p>","DOI":"10.5114\/reum.2015.53138","type":"journal-article","created":{"date-parts":[[2015,10,7]],"date-time":"2015-10-07T11:25:54Z","timestamp":1444217154000},"page":"157-160","source":"Crossref","is-referenced-by-count":2,"title":["Juvenile idiopathic arthritis complicated by amyloidosis with secondary nephrotic syndrome \u2013 effective treatment with tocilizumab"],"prefix":"10.5114","volume":"53","author":[{"given":"Ma\u0142gorzata","family":"Kwiatkowska","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ewa","family":"Jednacz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lidia","family":"Rutkowska-Sak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3061","published-online":{"date-parts":[[2015,8,7]]},"container-title":["Rheumatology"],"original-title":["M\u0142odzie\u0144cze idiopatyczne zapalenie staw\u00f3w powik\u0142ane amyloidoz\u0105 z wt\u00f3rnym zespo\u0142em nerczycowym \u2013 skuteczne leczenie tocilizumabem"],"link":[{"URL":"https:\/\/reu.termedia.pl\/pdf-57293-86460","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/reu.termedia.pl\/pdf-57293-86460","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,30]],"date-time":"2023-01-30T20:59:27Z","timestamp":1675112367000},"score":1,"resource":{"primary":{"URL":"https:\/\/reu.termedia.pl\/Juvenile-idiopathic-arthritis-complicated-by-amyloidosis-with-secondary-nephrotic,57293,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7,30]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015]]}},"alternative-id":["57293"],"URL":"https:\/\/doi.org\/10.5114\/reum.2015.53138","relation":{},"ISSN":["0034-6233","2084-9834"],"issn-type":[{"value":"0034-6233","type":"print"},{"value":"2084-9834","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,7,30]]}}}