{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:21:48Z","timestamp":1762867308722},"reference-count":9,"publisher":"Termedia Sp. z.o.o.","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Reumatologia"],"published-print":{"date-parts":[[2017,10,31]]},"abstract":"<jats:p>Granulomatosis with polyangiitis (GPA) is characterised by granulomatous necrotising inflammatory lesions of the upper and lower respiratory tract, often associated with pauci-immune glomerulonephritis. The diagnosis of granulomatosis with polyangiitis is made according to the classification criteria of the ACR criteria for granulomatosis with polyangiitis. We present two cases of granulomatosis with polyangiitis limited\/localised form. The common feature between two clinical cases were not sufficient criteria for a definite diagnosis at the beginning. In both cases the clinical presence was otitis media with acute mastoiditis, peripheral facial nerve palsy, and severe headache. Early diagnosis and treatment of patients with granulomatosis with polyangiitis define favourable prognosis. On the other hand, the treatment of granulomatosis with polyangiitis (corticosteroids and immunosuppressive therapy) has various side effects, and the \u201cex juvantibus\u201d therapy is hazardous.<\/jats:p>","DOI":"10.5114\/reum.2017.71643","type":"journal-article","created":{"date-parts":[[2017,12,20]],"date-time":"2017-12-20T13:26:41Z","timestamp":1513776401000},"page":"256-260","source":"Crossref","is-referenced-by-count":10,"title":["Two clinical cases of granulomatosis with polyangiitis with isolated otitis media and mastoiditis"],"prefix":"10.5114","volume":"55","author":[{"given":"Georgi","family":"Kukushev","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Desislava","family":"Kalinova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan","family":"Sheytanov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rasho","family":"Rashkov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3061","published-online":{"date-parts":[[2017,10,28]]},"reference":[{"key":"ref-795912","unstructured":"Stone JS. Wegener\u2019s granulomatosis. Rheumatology. Hochberg M, Silman A, Smolen J, et al. (eds.). Fifth ed, 2012; 1547-1557."},{"key":"ref-795913","doi-asserted-by":"crossref","unstructured":"Costa CF, Polanski JF. Wegener\u2019s granulomatosis. Arch Otorhinolaryngologia 2015; 19; 266-268.","DOI":"10.1055\/s-0034-1387164"},{"key":"ref-795914","doi-asserted-by":"crossref","unstructured":"Trimarchi M, Sinico RA, Teggi R, et al. Otorhinolaryngological manifestations in granulomatosis with polyangiitis (Wegener\u2019s granulomatosis). Autoimmun Rev 2012; 12; 501-505.","DOI":"10.1016\/j.autrev.2012.08.010"},{"key":"ref-795915","doi-asserted-by":"crossref","unstructured":"Devaney K, Travis W, Hoffman G, et al. Interpretation of head and neck biopsies in Wegener\u2019s granulomatosis. A pathological study of 126 biopsies in 70 patients. Am J Surg 1990; 14: 555.","DOI":"10.1097\/00000478-199006000-00006"},{"key":"ref-795916","doi-asserted-by":"crossref","unstructured":"Hunder GG, Arend WP, Bloch DA, et al. The American College of Rheumatology 1990 Criteria for the classification of vasculitis. Introduction. Arthritis Rheum 1990; 33: 1065-1067.","DOI":"10.1002\/art.1780330802"},{"key":"ref-795917","doi-asserted-by":"crossref","unstructured":"Bloch DA, Michel BA, Hunder GG, et al. The American College of Rheumatology 1990 Criteria for the classification of vasculitis. Patients and methods. Arthritis Rheum 1990; 33: 1068-1073.","DOI":"10.1002\/art.1780330803"},{"key":"ref-795918","doi-asserted-by":"crossref","unstructured":"Fires JF, Hunder GG, Bloch DA, et al. The American College of Rheumatology 1990 Criteria for the classification of vasculitis. Summary. Arthritis Rhem 1990; 33: 1135-1136.","DOI":"10.1002\/art.1780330812"},{"key":"ref-795919","doi-asserted-by":"crossref","unstructured":"Jenette JC, Falk RJ, Andrassy K, et al. Nomenclature of systemic vasculitides: proposal of an International Consensus Conference. Arthritis Rheum 1994; 37: 187-192.","DOI":"10.1002\/art.1780370206"},{"key":"ref-795920","unstructured":"Smith ME. The Pharynx and upper airway. In: Rudolph\u2019s pediatrics. Rudolph CD, Rudolph AM, Lister GE, et al. (eds.). 22nd ed. McGraw-Hill Companies, New York 2017."}],"container-title":["Rheumatology"],"original-title":[],"link":[{"URL":"https:\/\/reu.termedia.pl\/pdf-78672-86339","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/reu.termedia.pl\/pdf-78672-86339","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,30]],"date-time":"2023-01-30T20:54:49Z","timestamp":1675112089000},"score":1,"resource":{"primary":{"URL":"https:\/\/reu.termedia.pl\/Two-clinical-cases-of-granulomatosis-with-polyangiitis-with-isolated-otitis-media,78672,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,28]]},"references-count":9,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017]]}},"alternative-id":["78672"],"URL":"https:\/\/doi.org\/10.5114\/reum.2017.71643","relation":{},"ISSN":["0034-6233","2084-9834"],"issn-type":[{"value":"0034-6233","type":"print"},{"value":"2084-9834","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,28]]}}}