{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T04:15:58Z","timestamp":1692850558534},"reference-count":37,"publisher":"King Faisal Specialist Hospital and Research Centre","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Saudi Med"],"published-print":{"date-parts":[[1997,7]]},"DOI":"10.5144\/0256-4947.1997.395","type":"journal-article","created":{"date-parts":[[2017,5,16]],"date-time":"2017-05-16T13:46:05Z","timestamp":1494942365000},"page":"395-398","source":"Crossref","is-referenced-by-count":1,"title":["Application of Polymerase Chain Reaction to Detect Rearrangement of Immunoglobulin Heavy Chain Genes in Lymphoproliferative Disease"],"prefix":"10.5144","volume":"17","author":[{"given":"Salem H.","family":"Khalil","sequence":"first","affiliation":[{"name":"From the Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia."},{"name":"Address reprint requests and correspondence to Dr. Khalil: King Faisal Specialist Hospital and Research Centre, MBC 10, P.O. Box 3354, Riyadh, Saudi Arabia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen","family":"Siegrist","sequence":"additional","affiliation":[{"name":"From the Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Akhtar","sequence":"additional","affiliation":[{"name":"From the Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3134","published-online":{"date-parts":[[2017,4,21]]},"reference":[{"key":"10.5144\/0256-4947.1997.395_r1","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1038\/302575a0","article-title":"Somatic generation of antibody diversity","volume":"302","author":"Tonegawa","year":"1983","journal-title":"Nature"},{"key":"10.5144\/0256-4947.1997.395_r2","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.4049\/jimmunol.147.5.1720","article-title":"Multiple mechanisms participate in the generation of diversity of human H chain CDR3 regions","volume":"147","author":"Sanz","year":"1991","journal-title":"J Immunol"},{"key":"10.1520\/0256-4947.1997.395_r3","doi-asserted-by":"crossref","first-page":"511","DOI":"10.4049\/jimmunol.149.2.511","article-title":"The pattern of joining (JH) gene usage in the human IgH chain is established predominantly at the B precursor cell stage","volume":"149","author":"Wasserman","year":"1992","journal-title":"J Immunol"},{"key":"10.1520\/0256-4947.1997.395_r4","doi-asserted-by":"crossref","first-page":"9","DOI":"10.3109\/10428199109068100","article-title":"Detection of immunoglobulin gene rearrangement in B-cell neoplasms by polymerase chain reaction gene amplification","volume":"5","author":"Deane","year":"1991","journal-title":"Leuk Lymphoma"},{"key":"10.1520\/0256-4947.1997.395_r5","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1111\/j.1445-5994.1991.tb04695.x","article-title":"T-cell receptor and immunoglobulin gene rearrangement analysis as a laboratory aid in the diagnosis of human malignant lymphoproliferative disease","volume":"21","author":"Dietzsch","year":"1991","journal-title":"Aust N Z J Med"},{"key":"10.1520\/0256-4947.1997.395_r6","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1056\/NEJM198312293092601","article-title":"Immunoglobulin gene rearrangements as unique clonal markers in human lymphoid neoplasms","volume":"309","author":"Arnold","year":"1983","journal-title":"N Engl J Med"},{"key":"10.1520\/0256-4947.1997.395_r7","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1073\/pnas.81.2.593","article-title":"Immunoglobulin gene rearrangements as a diagnostic criterion of B-cell lymphoma","volume":"81","author":"Cleary","year":"1984","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1520\/0256-4947.1997.395_r8","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1172\/JCI110770","article-title":"Immunoglobulin gene rearrangement and cell surface antigen expression in acute lymphocytic leukemias of T-cell and B-cell precursor origins","volume":"71","author":"Korsmeyer","year":"1983","journal-title":"J Clin Invest"},{"key":"10.1520\/0256-4947.1997.395_r9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1445-5994.1987.tb05039.x","article-title":"Diagnostic use of immunoglobulin and T-cell receptor gene rearrangements in lymphoproliferative disease","volume":"17","author":"Story","year":"1987","journal-title":"Aust N Z J Med"},{"key":"10.1520\/0256-4947.1997.395_r10","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0738-081X(91)90002-3","article-title":"Gene rearrangement in lymphoid neoplasia","volume":"9","author":"Zelickson","year":"1991","journal-title":"Clinics Dermatol"},{"key":"10.1520\/0256-4947.1997.395_r11","unstructured":"Sklar JS, Weiss LM, Cleary ML. Diagnostic molecular biology of non-Hodgkinson's lymphomas. In: Berard CW, Dorfman RF, Kaufman N, eds. Malignant lymphoma. Baltimore: Williams and Wilkins, 1987:204-24."},{"key":"10.1520\/0256-4947.1997.395_r12","first-page":"117","article-title":"Molecular genetics and the diagnosis of lymphoma","volume":"112","author":"Cossman","year":"1988","journal-title":"Arch Pathol Lab Med"},{"key":"10.1520\/0256-4947.1997.395_r13","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1080\/00313029500169293","article-title":"The usefulness of a rapid PCR methodology to detect rearranged Ig heavy genes in lymphoproliferative diseases in a diagnostic setting","volume":"27","author":"Angulo","year":"1995","journal-title":"Pathology"},{"key":"10.1520\/0256-4947.1997.395_r14","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1097\/00019606-199503000-00004","article-title":"Polymerase chain reaction versus Southern blot hybridization, detection of immunoglobulin heavy chain gene rearrangements","volume":"4","author":"Sioutos","year":"1995","journal-title":"Diagn Mol Pathol"},{"key":"10.1520\/0256-4947.1997.395_r15","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1097\/00019606-199503000-00005","article-title":"Routine application of polymerase chain reaction in the diagnosis of monoclonality of B-cell lymphoid proliferations","volume":"4","author":"Achille","year":"1995","journal-title":"Diagn Mol Pathol"},{"key":"10.1520\/0256-4947.1997.395_r16","first-page":"357","article-title":"Utility of a rapid polymerase chain reaction panel for the detection of molecular changes in B-cell lymphoma","volume":"120","author":"Abdel-Reheim","year":"1996","journal-title":"Arch Pathol Lab Med"},{"key":"10.1520\/0256-4947.1997.395_r17","first-page":"726","article-title":"An improved method for detection of B-lymphoid clonality by polymerase chain reaction","volume":"5","author":"Deane","year":"1991","journal-title":"Leukemia"},{"key":"10.1520\/0256-4947.1997.395_r18","unstructured":"Sambrook J, Fritsch EF, Maniatis T. Molecular cloning: a laboratory manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory. 1989;E.3-E.4."},{"key":"10.1520\/0256-4947.1997.395_r19","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1182\/blood.V84.2.574.574","article-title":"Characterization of clone-specific rearranged T-cell receptor \u03b3-chain genes in lymphomas and leukemias by the polymerase chain reaction and DNA sequencing","volume":"84","author":"Kneba","year":"1994","journal-title":"Blood"},{"key":"10.1520\/0256-4947.1997.395_r20","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1182\/blood.V78.1.192.192","article-title":"Gene rearrangement in B- and T-lymphoproliferative disease detected by the polymerase chain reaction","volume":"78","author":"Trainor","year":"1991","journal-title":"Blood"},{"key":"10.1520\/0256-4947.1997.395_r21","doi-asserted-by":"crossref","first-page":"8536","DOI":"10.1073\/pnas.87.21.8536","article-title":"Rapid, nonradioactive detection of clonal T-cell receptor gene rearrangements in lymphoid neoplasms","volume":"87","author":"Bourgouin","year":"1990","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1520\/0256-4947.1997.395_r22","first-page":"171","article-title":"Comparison of PCR with Southern hybridization for the routine detection of immunoglobulin heavy chain gene rearrangements","volume":"103","author":"Lehman","year":"1995","journal-title":"AJCP"},{"key":"10.1520\/0256-4947.1997.395_r23","first-page":"1841","article-title":"Detection of clonal gene rearrangements by polymerase chain reaction, amplification and single-strand conformational polymorphism analysis","volume":"142","author":"Davis","year":"1993","journal-title":"Am J Pathol"},{"key":"10.1520\/0256-4947.1997.395_r24","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1136\/jcp.43.11.888","article-title":"Monoclonality in B-cell lymphoma detected in paraffin wax embedded sections using the polymerase chain reaction","volume":"43","author":"Wan","year":"1990","journal-title":"J Clin Pathol"},{"key":"10.1520\/0256-4947.1997.395_r25","doi-asserted-by":"crossref","first-page":"5123","DOI":"10.1073\/pnas.86.13.5123","article-title":"Detection of minimal disease in hematopoietic malignancies of the B-cell lineage by using third-complementary determining region (CDR-III) specific probes","volume":"86","author":"Yamada","year":"1989","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1520\/0256-4947.1997.395_r26","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1111\/j.1365-2141.1990.tb02643.x","article-title":"Development of a highly sensitive assay, based on the polymerase chain reaction, for rare B-lymphocyte clones in a polyclonal population","volume":"75","author":"Brisco","year":"1990","journal-title":"Br J Haematol"},{"key":"10.1520\/0256-4947.1997.395_r27","first-page":"471","article-title":"Description of a novel FRI IgH PCR strategy and its comparison with three other strategies for the detection of clonality in B cell malignancies","volume":"9","author":"Aubin","year":"1995","journal-title":"Leukemia"},{"key":"10.1520\/0256-4947.1997.395_r28","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/j.1365-2141.1990.tb02579.x","article-title":"Detection of immunoglobulin gene rearrangements in B lymphoid malignancies by polymerase chain reaction gene amplification","volume":"74","author":"Deane","year":"1990","journal-title":"Br J Haematol"},{"key":"10.1520\/0256-4947.1997.395_r29","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1002\/path.1711690303","article-title":"Detection of monoclonality in low-grade B-cell lymphomas using the polymerase chain reaction is dependent of primer selection and lymphoma type","volume":"169","author":"Diss","year":"1993","journal-title":"J Pathol"},{"key":"10.1520\/0256-4947.1997.395_r30","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1136\/jcp.45.9.770","article-title":"Improved PCR method for detecting monoclonal immunoglobulin heavy chain rearrangement in B cell neoplasms","volume":"45","author":"Ramasamy","year":"1992","journal-title":"J Clin Pathol"},{"key":"10.1520\/0256-4947.1997.395_r31","first-page":"840","article-title":"Identification and structural analysis of rearranged immunoglobulin heavy chain genes in lymphomas and leukemias","volume":"9","author":"Linke","year":"1995","journal-title":"Leukemia"},{"key":"10.1520\/0256-4947.1997.395_r32","first-page":"746","article-title":"Detection of immunoglobulin gene rearrangements in B-cell non-Hodgkin's lymphomas and leukemias in fresh, unfixed and formalin-fixed, paraffin-embedded tissue by polymerase chain reaction","volume":"68","author":"Inghirami","year":"1993","journal-title":"Lab Invest"},{"key":"10.1520\/0256-4947.1997.395_r33","doi-asserted-by":"crossref","first-page":"289","DOI":"10.3109\/10428199209049780","article-title":"Variable rate of detection of immunoglobulin heavy chain V-D-J rearrangement by PCR: a systematic study of 41 B-cell non-Hodgkin's lymphomas and leukemias","volume":"7","author":"Ben Ezra","year":"1992","journal-title":"Leuk Lymphoma"},{"key":"10.1520\/0256-4947.1997.395_r34","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1002\/ajh.2830430107","article-title":"Detection of immunoglobulin gene rearrangements in lymphoid malignancies of B-cell lineage by seminested polymerase chain reaction gene amplification","volume":"43","author":"Liang","year":"1993","journal-title":"Am J Hematol"},{"key":"10.1520\/0256-4947.1997.395_r35","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1016\/0046-8177(94)90084-1","article-title":"Optimal primer selection for clonality assessment by polymerase chain reaction analysis: (1) Low grade B-cell lymphoproliferative disorders of nonfollicular cell type","volume":"25","author":"Segal","year":"1994","journal-title":"Hum Pathol"},{"key":"10.1520\/0256-4947.1997.395_r36","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1084\/jem.169.3.613","article-title":"Translocation t(14;18) in B-cell polymerase as a cause for defective immunoglobulin production","volume":"169","author":"De Jong","year":"1989","journal-title":"J Exp Med"},{"key":"10.1520\/0256-4947.1997.395_r37","doi-asserted-by":"crossref","first-page":"3021","DOI":"10.1182\/blood.V78.11.3021.3021","article-title":"Analysis of B-lymphoid malignancies using allele-specific polymerase chain reaction: a technique for sequential quantitation of residual disease","volume":"78","author":"Billadeau","year":"1991","journal-title":"Blood"}],"container-title":["Annals of Saudi Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.annsaudimed.net\/index.php\/vol17\/vol17iss4\/2983.html","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T15:53:08Z","timestamp":1692805988000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.annsaudimed.net\/index.php\/vol17\/vol17iss4\/2983.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,7]]},"references-count":37,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1997,7]]}},"URL":"https:\/\/doi.org\/10.5144\/0256-4947.1997.395","relation":{},"ISSN":["0256-4947","0975-4466"],"issn-type":[{"value":"0256-4947","type":"print"},{"value":"0975-4466","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,7]]}}}