{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T03:12:04Z","timestamp":1787800324035,"version":"build-2784847793"},"reference-count":12,"publisher":"King Faisal Specialist Hospital and Research Centre","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Saudi Med"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:p>Myometrium myxoidosis is new terminology to describe a non-neo-plastic process of extracellular mucinous accumulation in the myometrium wall of the uterus. We report a rare association of myometrial myxoidosis with lupus erythematosus in a 35-year old woman with a history of leiomyoma. At presentation, this case was diagnosed as a pelvic abscess and treated with specific antibiotherapy, and then discharged after clinical improvement. One week later, after recurrence of the symptoms, the patient underwent hysterectomy with bilateral salpingo-oophorectomy and appendectomy with anterior abdominal soft tissue part resection. Pathological analysis revealed diffuse hypo-cellular myxoid areas intersecting the smooth muscle layer of the uterus and cervix in addition to a focal area in the interstitium of smooth muscles of the appendix and soft tissue of the anterior abdominal wall. This case emphasizes the importance of distinguishing between myxoid neoplastic and non-neoplastic lesions with myxoid changes.<\/jats:p>\n          <jats:sec>\n            <jats:title>SIMILAR CASES PUBLISHED:<\/jats:title>\n            <jats:p>To our knowledge, there are only two similar cases reported.<\/jats:p>\n          <\/jats:sec>","DOI":"10.5144\/0256-4947.2021.121","type":"journal-article","created":{"date-parts":[[2021,4,5]],"date-time":"2021-04-05T12:14:36Z","timestamp":1617624876000},"page":"121-126","source":"Crossref","is-referenced-by-count":1,"title":["Myometrial myxoidosis in a patient with systemic lupus erythematosus"],"prefix":"10.5144","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5230-8352","authenticated-orcid":true,"given":"Doaa Ali","family":"Alghamdi","sequence":"first","affiliation":[{"name":"From the Department of Pathology, King Abdulaziz University, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3134","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"crossref","first-page":"243","DOI":"10.4103\/0377-4929.81582","article-title":"Uterine mesenchymal tumors","volume":"54","author":"Sangle NA","year":"2011","unstructured":"Sangle NA, Lele SM. Uterine mesenchymal tumors. Indian J Pathol Microbiol 2011;54:243-53.","journal-title":"Indian J Pathol Microbiol"},{"key":"e_1_3_3_3_2","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1097\/PGP.0b013e3181c6a79a","article-title":"Myxoid Change of the Myometrium and Cervical Stroma: Description of a Hitherto Unreported Non-neoplastic Phenomenon With Discussion of Myxoid Uterine Lesions","volume":"29","author":"McCluggage WG","year":"2010","unstructured":"McCluggage WG, Young RH. Myxoid Change of the Myometrium and Cervical Stroma: Description of a Hitherto Unreported Non-neoplastic Phenomenon With Discussion of Myxoid Uterine Lesions. 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Myxoid endometrial stromal sarcoma of the uterus. Pathol Int 2003;53:637-41.","journal-title":"Pathol Int"},{"key":"e_1_3_3_6_2","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/S0046-8177(00)80258-0","article-title":"Uterine myxoid leiomyosarcoma within a leiomyoma","volume":"31","author":"Mittal K","year":"2000","unstructured":"Mittal K, Popiolek D, Demopoulos R. Uterine myxoid leiomyosarcoma within a leiomyoma. Hum Pathol 2000;31:398-400.","journal-title":"Hum Pathol"},{"key":"e_1_3_3_7_2","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1007\/s002610000102","article-title":"Myxoid leiomyoma of the uterus: CT and MRI features","volume":"26","author":"Cruz M","year":"2001","unstructured":"Cruz M, Murakami T, Tsuda K, Kurachi H, Enomoto T, Kim T, et al Myxoid leiomyoma of the uterus: CT and MRI features. 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