{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T11:45:51Z","timestamp":1783943151559,"version":"3.55.0"},"reference-count":23,"publisher":"King Faisal Specialist Hospital and Research Centre","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Saudi Med"],"published-print":{"date-parts":[[2023,1]]},"abstract":"\n BACKGROUND:<\/jats:title>\n Although obstetric morbidity and mortality have decreased recently, rates are still high enough to constitute a significant health problem. With the COVID-19 pandemic, many obstetric patients have required treatment in intensive care units (ICU).<\/jats:p>\n <\/jats:sec>\n \n OBJECTIVES:<\/jats:title>\n Evaluate critical obstetric patients who were treated in an ICU for COVID-19 and followed up for 90 days.<\/jats:p>\n <\/jats:sec>\n \n DESIGN:<\/jats:title>\n Medical record review<\/jats:p>\n <\/jats:sec>\n \n SETTING:<\/jats:title>\n Intens\u0131ve care unit<\/jats:p>\n <\/jats:sec>\n \n PAT\u0130ENTS AND METHODS:<\/jats:title>\n Obstetric patients admitted to the ICU between 15 March 2020 and 15 March 2022 and followed up for at least 90 days were evaluated retrospectively. Patients with and without COVID-19 were compared by gestational week, indications, comorbidities, length of stay in the hospital and ICU, requirement for mechanical ventilation, blood transfusion, renal replacement therapy (RRT), plasmapheresis, ICU scores, and mortality.<\/jats:p>\n <\/jats:sec>\n \n MAIN OUTCOME MEASURES:<\/jats:title>\n Clinical outcomes and mortality.<\/jats:p>\n <\/jats:sec>\n \n SAMPLE SIZE AND CHARACTERISTICS:<\/jats:title>\n 102 patients with a mean (SD) maternal age of 29.1 (6.3) years, and median (IQR) length of gestation of 35.0 (7.8) weeks.<\/jats:p>\n <\/jats:sec>\n \n RESULTS:<\/jats:title>\n \n About 30% (n=31) of the patients were positive for COVID-19. Most (87.2%) were cesarean deliveries; 4.9% vaginal (8.7% did not deliver). COVID-19, eclampsia\/preeclampsia, and postpartum hemorrhage were the most common ICU indications. While the 28-day mortality was 19.3% (n=6) in the COVID-19 group, it was 1.4% (n=1) in the non-COVID-19 group (\n P<\/jats:italic>\n <.001). The gestational period was significantly shorter in the COVID-19 group (\n P<\/jats:italic>\n =.01) while the duration of stay in ICU (\n P<\/jats:italic>\n <.001) and mechanical ventilation (\n P<\/jats:italic>\n =.03), lactate (\n P<\/jats:italic>\n =.002), blood transfusions (\n P<\/jats:italic>\n =.001), plasmapheresis requirements (\n P<\/jats:italic>\n =.02), and 28-day mortality were significantly higher (\n P<\/jats:italic>\n <.001). APACHE-2 scores (\n P<\/jats:italic>\n =.007), duration of stay in ICU (\n P<\/jats:italic>\n <.001) and mechanical ventilation (\n P<\/jats:italic>\n <.001), RRT (\n P<\/jats:italic>\n =.007), and plasmapheresis requirements (\n P<\/jats:italic>\n =.005) were significantly higher in patients who died than in those who were discharged.\n <\/jats:p>\n <\/jats:sec>\n \n CONCLUSION:<\/jats:title>\n The most common indication for ICU admission was COVID-19. The APACHE-2 scoring was helpful in predicting mortality. We think multicenter studies with larger sample sizes are needed for COVID-19 obstetric patients. In addition to greater mortality and morbidity, the infection may affect newborn outcomes by causing premature birth.<\/jats:p>\n <\/jats:sec>\n \n LIMITATIONS:<\/jats:title>\n Retrospect\u0131ve, single-center, small population size.<\/jats:p>\n <\/jats:sec>\n \n CONFLICT OF INTEREST:<\/jats:title>\n None.<\/jats:p>\n <\/jats:sec>","DOI":"10.5144\/0256-4947.2023.10","type":"journal-article","created":{"date-parts":[[2023,2,5]],"date-time":"2023-02-05T08:01:52Z","timestamp":1675584112000},"page":"10-16","source":"Crossref","is-referenced-by-count":11,"title":["Evaluation of critically ill obstetric patients treated in an intensive care unit during the COVID-19 pandemic"],"prefix":"10.5144","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4061-0746","authenticated-orcid":true,"given":"Kadir","family":"Arslan","sequence":"first","affiliation":[{"name":"From the Department of Anesthesiology and Intensive Care, Istanbul Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hale \u00c7etin","family":"Arslan","sequence":"additional","affiliation":[{"name":"From the Department of Gynecology and Obstetrics, Istanbul Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayca Sultan","family":"\u015eahin","sequence":"additional","affiliation":[{"name":"From the Department of Anesthesiology and Intensive Care, Istanbul Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3134","reference":[{"key":"e_1_3_2_2_2","unstructured":"World Health Statistics 2018: Monitoring healthstatisticreports for the SDGs sustainable development goals. 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