{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T17:27:30Z","timestamp":1774459650127,"version":"3.50.1"},"reference-count":40,"publisher":"King Faisal Specialist Hospital and Research Centre","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Saudi Med"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:sec>\n            <jats:title>BACKGROUND:<\/jats:title>\n            <jats:p>In adults with acute respiratory distress syndrome (ARDS), high-frequency oscillatory ventilation (HFOV) has been associated with higher mortality rates. Therefore, its use in children with ARDS is still controversial.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>OBJECTIVES:<\/jats:title>\n            <jats:p>Evaluate the overall mortality of HFOV in children with ARDS and explore mortality-related risk factors; compare the outcome of using HFOV post-endotracheal intubation early (\u226424 hours) versus late (\u226424 hours).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>DESIGN:<\/jats:title>\n            <jats:p>Retrospective (medical record review)<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>SETTING:<\/jats:title>\n            <jats:p>Pediatric intensive care unit in a tertiary care center in Saudi Arabia.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>PATIENTS AND METHODS:<\/jats:title>\n            <jats:p>Data were collected from medical records of all pediatric patients with ARDS aged one week to 14 years, who were admitted to the pediatric intensive care unit (PICU) from January 2016-June 2019 and who required HFOV.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>MAIN OUTCOME MEASURES:<\/jats:title>\n            <jats:p>PICU mortality.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>SAMPLE SIZE AND CHARACTERISTICS:<\/jats:title>\n            <jats:p>135 ARDS patients including 74 females (54.8%), and 61 males (45.2%), with a median age (interquar-tile range) of 35 (72) months.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>RESULTS:<\/jats:title>\n            <jats:p>\n              The overall mortality rate was 60.0% (81\/135), and most died in the first 28 days in the PICU (91.3%, 74\/8). Of non-survivors, 75.3% (61\/81) were immunocompromised, and 24.7% (20\/81) were immuno-competent patients, 52 (64.2%) received inotropic support, 40 (49.4%) had a bone-marrow transplant (BMT) before HFOV initiation. Although the prone position was used in 20.7% (28\/135) to improve the survival rate post-HFOV ventilation, only 28.6% (8\/28) survived. In addition, altered code status or chemotherapy reported a significant association with mortality (\n              <jats:italic>P<\/jats:italic>\n              &lt;.05). Interestingly, early HFOV initiation (\u226424 hours) did not seem to have a high impact on survival compared to late initiation (&gt;24 hours); (57.4% vs. 42.6%,\n              <jats:italic>P<\/jats:italic>\n              =.721).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>CONCLUSION:<\/jats:title>\n            <jats:p>Immunocompromised and oncology patients, including post-BMT, reported poorer outcomes, and neither the prone position nor early use of HFOV improved outcomes. However, it is recommended to replicate the study in a larger cohort to generalize the results.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>LIMITATIONS:<\/jats:title>\n            <jats:p>Retrospective single-center study.<\/jats:p>\n          <\/jats:sec>","DOI":"10.5144\/0256-4947.2023.283","type":"journal-article","created":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T08:58:48Z","timestamp":1696841928000},"page":"283-290","source":"Crossref","is-referenced-by-count":3,"title":["The outcome of high-frequency oscillatory ventilation in pediatric patients with acute respiratory distress syndrome in an intensive care unit"],"prefix":"10.5144","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7525-3529","authenticated-orcid":false,"given":"Tareq","family":"Al-Ayed","sequence":"first","affiliation":[{"name":"From the Critical Care Medicine Department, Pediatric Intensive Care Unit, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iyad B.","family":"Alsarhi","sequence":"additional","affiliation":[{"name":"From the Pediatric Intensive Care Unit, International Medical Center, Jeddah, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdullah","family":"Alturki","sequence":"additional","affiliation":[{"name":"From the Critical Care Medicine Department, Pediatric Intensive Care Unit, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fahad","family":"Aljofan","sequence":"additional","affiliation":[{"name":"From the Critical Care Medicine Department, Pediatric Intensive Care Unit, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tariq","family":"Alofisan","sequence":"additional","affiliation":[{"name":"From the Critical Care Medicine Department, Pediatric Intensive Care Unit, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moath Al","family":"Abdulsalam","sequence":"additional","affiliation":[{"name":"From the Critical Care Medicine Department, Pediatric Intensive Care Unit, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deema","family":"Gashgarey","sequence":"additional","affiliation":[{"name":"From the Department of Pediatrics, King Faisal Specialist Hospital and Research Center, Riyadh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rwan","family":"Alrwili","sequence":"additional","affiliation":[{"name":"From the Department of Pediatrics, King Faisal Specialist Hospital and Research Center, Riyadh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wala","family":"Aldihan","sequence":"additional","affiliation":[{"name":"From the Department of Pediatrics, King Faisal Specialist Hospital and Research Center, Riyadh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saleh Badr Bin","family":"Mahfodh","sequence":"additional","affiliation":[{"name":"From the Pediatric Intensive Care Unit, International Medical Center, Jeddah, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fawaz","family":"Alanzi","sequence":"additional","affiliation":[{"name":"From the Department of Pediatrics, King Faisal Specialist Hospital and Research Center, Riyadh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed M.","family":"Al-Wathinani","sequence":"additional","affiliation":[{"name":"From the Emergency Medical Services, King Saud University, Riyadh, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raghad Tariq","family":"Alhuthil","sequence":"additional","affiliation":[{"name":"From the Department of Pediatrics, King Faisal Specialist Hospital and Research Center, Riyadh"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3134","reference":[{"issue":"7","key":"e_1_3_3_2_2","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1097\/CCM.0000000000002406","article-title":"Disassociating Lung Mechanics and Oxygenation in Pediatric Acute Respiratory Distress Syndrome","volume":"45","author":"Yehya N","year":"2017","unstructured":"Yehya N, Thomas NJ. Disassociating Lung Mechanics and Oxygenation in Pediatric Acute Respiratory Distress Syndrome. Crit Care Med. 2017 Jul;45(7):1232\u20131239.","journal-title":"Crit Care Med"},{"issue":"18","key":"e_1_3_3_3_2","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1056\/NEJM200005043421801","article-title":"Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome","volume":"342","author":"Acute Respiratory Distress Syndrome Network","year":"2000","unstructured":"Acute Respiratory Distress Syndrome Network; Brower RG, Matthay MA, Morris A, Schoenfeld D, Thompson BT, Wheeler A. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med. 2000 May 4;342(18):1301\u20138.","journal-title":"N Engl J Med"},{"issue":"1","key":"e_1_3_3_4_2","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1164\/rccm.201707-1404OC","article-title":"Positive End-Expiratory Pressure Lower Than the ARDS Network Protocol Is Associated with Higher Pediatric Acute Respiratory Distress Syndrome Mortality","volume":"198","author":"Khemani RG","year":"2018","unstructured":"Khemani RG, Parvathaneni K, Yehya N, Bhalla AK, Thomas NJ, Newth CJL. Positive End-Expiratory Pressure Lower Than the ARDS Network Protocol Is Associated with Higher Pediatric Acute Respiratory Distress Syndrome Mortality. Am J Respir Crit Care Med. 2018 Jul 1;198(1):77\u201389.","journal-title":"Am J Respir Crit Care Med"},{"issue":"5","key":"e_1_3_3_5_2","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1378\/chest.09-2415","article-title":"Severe hypoxemic respiratory failure","volume":"137","author":"Esan A","year":"2010","unstructured":"Esan A, Hess DR, Raoof S, George L, Sessler CN. Severe hypoxemic respiratory failure. Chest. 2010;137(5):1203\u201316.","journal-title":"Chest"},{"issue":"4","key":"e_1_3_3_6_2","first-page":"S435","article-title":"Acute respiratory distress syndrome and pneumothorax","volume":"6","author":"Terzi E","year":"2014","unstructured":"Terzi E, Zarogoulidis K, Kougioumtzi I, Dryllis G, Kioumis I, Pitsiou G, et al. Acute respiratory distress syndrome and pneumothorax. J Thorac Dis. 2014 Oct;6(Suppl 4):S435\u201342.","journal-title":"J Thorac Dis"},{"issue":"1","key":"e_1_3_3_7_2","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1164\/ajrccm.157.1.9604014","article-title":"Ventilator-induced lung injury: lessons from experimental studies","volume":"157","author":"Dreyfuss D","year":"1998","unstructured":"Dreyfuss D, Saumon G. Ventilator-induced lung injury: lessons from experimental studies. Am J Respir Crit Care Med. 1998 Jan;157(1):294\u2013323.","journal-title":"Am J Respir Crit Care Med"},{"issue":"11","key":"e_1_3_3_8_2","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1097\/PCC.0000000000001305","article-title":"Association of Response to Inhaled Nitric Oxide and Duration of Mechanical Ventilation in Pediatric Acute Respiratory Distress Syndrome","volume":"18","author":"Dowell JC","year":"2017","unstructured":"Dowell JC, Thomas NJ, Yehya N. Association of Response to Inhaled Nitric Oxide and Duration of Mechanical Ventilation in Pediatric Acute Respiratory Distress Syndrome. Pediatr Crit Care Med. 2017 Nov;18(11):1019\u20131026.","journal-title":"Pediatr Crit Care Med"},{"issue":"1","key":"e_1_3_3_9_2","first-page":"P035","article-title":"The importance of prone position ventilation in ARDS for the improvement of oxygenation index","volume":"3","author":"Lewejohann JC","year":"1999","unstructured":"Lewejohann JC, D\u00fcpree HJ, Glei\u03b2 J, Lewe-johann S, Muhl E, Bruch HP. The importance of prone position ventilation in ARDS for the improvement of oxygenation index. Crit Care. 1999;3(Suppl 1):P035.","journal-title":"Crit Care"},{"issue":"2","key":"e_1_3_3_10_2","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1001\/jama.294.2.229","article-title":"Effect of prone positioning on clinical outcomes in children with acute lung injury","volume":"294","author":"Curley MA","year":"2005","unstructured":"Curley MA, Hibberd PL, Fineman LD, Wypij D, Shih M-C, Thompson JE, et al. Effect of prone positioning on clinical outcomes in children with acute lung injury. JAMA. 2005;294(2):229.","journal-title":"JAMA"},{"issue":"1","key":"e_1_3_3_11_2","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1152\/jappl.1954.7.1.27","article-title":"Alveolar ventilation at very low tidal volumes","volume":"7","author":"Briscoe WA","year":"1954","unstructured":"Briscoe WA, Forster RE, Comroe JH Jr. Alveolar ventilation at very low tidal volumes. J Appl Physiol. 1954 Jul;7(1):27\u201330.","journal-title":"J Appl Physiol"},{"issue":"5","key":"e_1_3_3_12_2","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1378\/chest.08-0743","article-title":"Pressure characteristics of mechanical ventilation and incidence of pneumothorax before and after the implementation of protective lung strategies in the management of pediatric patients with severe Ards","volume":"134","author":"Miller MP","year":"2008","unstructured":"Miller MP, Sagy M. Pressure characteristics of mechanical ventilation and incidence of pneumothorax before and after the implementation of protective lung strategies in the management of pediatric patients with severe Ards. Chest. 2008;134(5):969\u201373.","journal-title":"Chest"},{"issue":"4","key":"e_1_3_3_13_2","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/S0022-3476(96)70122-1","article-title":"High-frequency pressure-control ventilation with high positive end-expiratory pressure in children with acute respiratory distress syndrome","volume":"129","author":"Paulson TE","year":"1996","unstructured":"Paulson TE, Spear RM, Silva PD, Peterson BM. High-frequency pressure-control ventilation with high positive end-expiratory pressure in children with acute respiratory distress syndrome. J Pediatr. 1996 Oct;129(4):566\u201373.","journal-title":"J Pediatr"},{"issue":"5","key":"e_1_3_3_14_2","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1097\/PCC.0000000000000350","article-title":"Pediatric acute respiratory distress syndrome: consensus recommendations from the Pediatric Acute Lung Injury Consensus Conference","volume":"16","author":"Pediatric Acute Lung Injury Consensus Conference Group","year":"2015","unstructured":"Pediatric Acute Lung Injury Consensus Conference Group. Pediatric acute respiratory distress syndrome: consensus recommendations from the Pediatric Acute Lung Injury Consensus Conference. Pediatr Crit Care Med. 2015 Jun;16(5):428\u201339.","journal-title":"Pediatr Crit Care Med"},{"issue":"314","key":"e_1_3_3_15_2","first-page":"1","article-title":"CDC growth charts: United States","author":"Kuczmarski RJ","year":"2000","unstructured":"Kuczmarski RJ, Ogden CL, Grummer-Strawn LM, Flegal KM, Guo SS, Wei R, et al. CDC growth charts: United States. Adv Data. 2000 Jun 8;(314):1\u201327.","journal-title":"Adv Data"},{"issue":"4","key":"e_1_3_3_16_2","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1055\/s-0038-1673671","article-title":"Comparison of Pediatric Risk of Mortality III, Pediatric Index of Mortality 2, and Pediatric Index of Mortality 3 in Predicting Mortality in a Pediatric Intensive Care Unit","volume":"7","author":"Tyagi P","year":"2018","unstructured":"Tyagi P, Tullu MS, Agrawal M. Comparison of Pediatric Risk of Mortality III, Pediatric Index of Mortality 2, and Pediatric Index of Mortality 3 in Predicting Mortality in a Pediatric Intensive Care Unit. J Pediatr Intensive Care. 2018 Dec;7(4):201\u2013206.","journal-title":"J Pediatr Intensive Care"},{"issue":"2","key":"e_1_3_3_17_2","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1097\/00003246-199302000-00002","article-title":"High-frequency oscillatory ventilation in pediatric critical care","volume":"21","author":"Kinsella JP","year":"1993","unstructured":"Kinsella JP, Clark RH. High-frequency oscillatory ventilation in pediatric critical care. Crit Care Med. 1993 Feb;21(2):174\u20135.","journal-title":"Crit Care Med"},{"issue":"4","key":"e_1_3_3_18_2","doi-asserted-by":"crossref","first-page":"R430","DOI":"10.1186\/cc3737","article-title":"High frequency oscillatory ventilation compared with conventional mechanical ventilation in adult respiratory distress syndrome: a randomized controlled trial [ISRCTN24242669]","volume":"9","author":"Bollen CW","year":"2005","unstructured":"Bollen CW, van Well GT, Sherry T, Beale RJ, Shah S, Findlay G, et al. High frequency oscillatory ventilation compared with conventional mechanical ventilation in adult respiratory distress syndrome: a randomized controlled trial [ISRCTN24242669]. Crit Care. 2005 Aug;9(4):R430\u20139.","journal-title":"Crit Care"},{"issue":"6","key":"e_1_3_3_19_2","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1016\/j.chest.2017.06.025","article-title":"High-frequency oscillatory ventilation in adults with Ards","volume":"152","author":"Sklar MC","year":"2017","unstructured":"Sklar MC, Fan E, Goligher EC. High-frequency oscillatory ventilation in adults with Ards. Chest. 2017;152(6):1306\u201317.","journal-title":"Chest"},{"key":"e_1_3_3_20_2","article-title":"G235(p) high frequency oscillatory ventilation in pediatric practice: A Single Center experience","author":"Gabr R","year":"2020","unstructured":"Gabr R, Nishil M, Zahraa J. G235(p) high frequency oscillatory ventilation in pediatric practice: A Single Center experience. APEM. 2020;","journal-title":"APEM"},{"issue":"3","key":"e_1_3_3_21_2","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1001\/jamapediatrics.2013.4463","article-title":"Comparison of high-frequency oscillatory ventilation and conventional mechanical ventilation in pediatric respiratory failure","volume":"168","author":"Gupta P","year":"2014","unstructured":"Gupta P, Green JW, Tang X, Gall CM, Gossett JM, Rice TB, Kacmarek RM, Wetzel RC. Comparison of high-frequency oscillatory ventilation and conventional mechanical ventilation in pediatric respiratory failure. JAMA Pediatr. 2014 Mar;168(3):243\u20139.","journal-title":"JAMA Pediatr"},{"issue":"4","key":"e_1_3_3_22_2","doi-asserted-by":"crossref","first-page":"404","DOI":"10.4187\/respcare.05765","article-title":"High-Frequency Oscillatory Ventilation Use and Severe Pediatric ARDS in the Pediatric Hematopoietic Cell Transplant Recipient","volume":"63","author":"Rowan CM","year":"2018","unstructured":"Rowan CM, Loomis A, McArthur J, Smith LS, Gertz SJ, Fitzgerald JC, et al. High-Frequency Oscillatory Ventilation Use and Severe Pediatric ARDS in the Pediatric Hematopoietic Cell Transplant Recipient. Respir Care. 2018 Apr;63(4):404\u2013411.","journal-title":"Respir Care"},{"issue":"5","key":"e_1_3_3_23_2","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1164\/rccm.201507-1381OC","article-title":"Early High-Frequency Oscillatory Ventilation in Pediatric Acute Respiratory Failure. A Propensity Score Analysis","volume":"193","author":"Bateman ST","year":"2016","unstructured":"Bateman ST, Borasino S, Asaro LA, Cheifetz IM, Diane S, Wypij D, et al. Early High-Frequency Oscillatory Ventilation in Pediatric Acute Respiratory Failure. A Propensity Score Analysis. Am J Respir Crit Care Med. 2016 Mar 1;193(5):495\u2013503.","journal-title":"Am J Respir Crit Care Med"},{"issue":"3","key":"e_1_3_3_24_2","doi-asserted-by":"crossref","first-page":"R274","DOI":"10.1186\/cc3520","article-title":"High-frequency oscillatory ventilation in children: a single-center experience of 53 cases","volume":"9","author":"Slee-Wijffels FY","year":"2005","unstructured":"Slee-Wijffels FY, van der Vaart KR, Twisk JW, Markhorst DG, Pl\u00f6tz FB. High-frequency oscillatory ventilation in children: a single-center experience of 53 cases. Crit Care. 2005 Jun;9(3):R274\u20139.","journal-title":"Crit Care"},{"issue":"1","key":"e_1_3_3_25_2","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.jped.2013.02.008","article-title":"High-frequency oscillatory ventilation in children: a 10-year experience","volume":"89","author":"Moniz M","year":"2013","unstructured":"Moniz M, Silvestre C, Nunes P, Abadesso C, Matias E, Loureiro H, et al. High-frequency oscillatory ventilation in children: a 10-year experience. J Pediatr (Rio J). 2013 Jan-Feb;89(1):48\u201355.","journal-title":"J Pediatr (Rio J)"},{"issue":"10","key":"e_1_3_3_26_2","doi-asserted-by":"crossref","first-page":"2162","DOI":"10.1097\/01.CCM.0000181298.05474.2B","article-title":"Comparison of prone positioning and high-frequency oscillatory ventilation in patients with acute respiratory distress syndrome","volume":"33","author":"Papazian L","year":"2005","unstructured":"Papazian L, Gainnier M, Marin V, Donati S, Arnal JM, Demory D, et al. Comparison of prone positioning and high-frequency oscillatory ventilation in patients with acute respiratory distress syndrome. Crit Care Med. 2005 Oct;33(10):2162\u201371.","journal-title":"Crit Care Med"},{"issue":"1","key":"e_1_3_3_27_2","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1097\/01.CCM.0000251128.60336.FE","article-title":"High-frequency oscillatory ventilation following prone positioning prevents a further impairment in oxygenation","volume":"35","author":"Demory D","year":"2007","unstructured":"Demory D, Michelet P, Arnal J-M, Donati S, Forel J-M, Gainnier M, et al. High-frequency oscillatory ventilation following prone positioning prevents a further impairment in oxygenation. Crit Care Med. 2007;35(1):106\u201311.","journal-title":"Crit Care Med"},{"key":"e_1_3_3_28_2","doi-asserted-by":"crossref","first-page":"926686","DOI":"10.3389\/fped.2022.926686","article-title":"Performance of Pediatric Risk of Mortality III and Pediatric Index of Mortality III Scores in Tertiary Pediatric Intensive Unit in Saudi Arabia","volume":"10","author":"Alkhalifah AS","year":"2022","unstructured":"Alkhalifah AS, AlSoqati A, Zahraa J. Performance of Pediatric Risk of Mortality III and Pediatric Index of Mortality III Scores in Tertiary Pediatric Intensive Unit in Saudi Arabia. Front Pediatr. 2022 Jul 7;10:926686.","journal-title":"Front Pediatr"},{"issue":"9","key":"e_1_3_3_29_2","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1056\/NEJMoa012750","article-title":"High-frequency oscillatory ventilation versus conventional mechanical ventilation for very-low-birth-weight infants","volume":"347","author":"Courtney SE","year":"2002","unstructured":"Courtney SE, Durand DJ, Asselin JM, Hudak ML, Aschner JL, Shoemaker CT; Neonatal Ventilation Study Group. High-frequency oscillatory ventilation versus conventional mechanical ventilation for very-low-birth-weight infants. N Engl J Med. 2002 Aug 29;347(9):643\u201352.","journal-title":"N Engl J Med"},{"issue":"4","key":"e_1_3_3_30_2","first-page":"CD004085","article-title":"High-frequency oscillatory ventilation versus conventional ventilation for acute respiratory distress syndrome","volume":"4","author":"Sud S","year":"2016","unstructured":"Sud S, Sud M, Friedrich JO, Wunsch H, Meade MO, Ferguson ND, et al. High-frequency oscillatory ventilation versus conventional ventilation for acute respiratory distress syndrome. Cochrane Database Syst Rev. 2016 Apr 4;4(4):CD004085.","journal-title":"Cochrane Database Syst Rev"},{"issue":"9","key":"e_1_3_3_31_2","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1056\/NEJMoa1215554","article-title":"High-frequency oscillation in early acute respiratory distress syndrome","volume":"368","author":"Ferguson ND","year":"2013","unstructured":"Ferguson ND, Cook DJ, Guyatt GH, Mehta S, Hand L, Austin P, et al. High-frequency oscillation in early acute respiratory distress syndrome. N Engl J Med. 2013 Feb 28;368(9):795\u2013805.","journal-title":"N Engl J Med"},{"key":"e_1_3_3_32_2","unstructured":"Naorungroj T Vilaichone W Tongyoo S Thamrongpairoj P Permpikul C. High-Frequency Oscillatory Ventilation for Patients during Exudative Phase of Severe ARDS [Internet]. ThaiScience. 2015 [cited 2023 Jan 12]. Available from: https:\/\/www.thaiscience.info\/journals\/Article\/JMAT\/10971109.pdf"},{"issue":"9","key":"e_1_3_3_33_2","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1056\/NEJMe020080","article-title":"High-frequency oscillatory ventilation to prevent bronchopulmonary dysplasia\u2014are we there yet?","volume":"347","author":"Stark AR","year":"2002","unstructured":"Stark AR. High-frequency oscillatory ventilation to prevent bronchopulmonary dysplasia\u2014are we there yet? N Engl J Med. 2002 Aug 29;347(9):682\u20134.","journal-title":"N Engl J Med"},{"issue":"1","key":"e_1_3_3_34_2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0378-3782(93)90088-C","article-title":"A multicenter randomized trial of high frequency oscillatory ventilation as compared with conventional mechanical ventilation in preterm infants with respiratory failure","volume":"32","author":"Ogawa Y","year":"1993","unstructured":"Ogawa Y, Miyasaka K, Kawano T, Imura S, Inukai K, Okuyama K, et al. A multicenter randomized trial of high frequency oscillatory ventilation as compared with conventional mechanical ventilation in preterm infants with respiratory failure. Early Hum Dev. 1993 Feb;32(1):1\u201310.","journal-title":"Early Hum Dev"},{"issue":"2","key":"e_1_3_3_35_2","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1542\/peds.107.2.363","article-title":"Prospective randomized multicenter comparison of high-frequency oscillatory ventilation and conventional ventilation in preterm infants of less than 30 weeks with respiratory distress syndrome","volume":"107","author":"Moriette G","year":"2001","unstructured":"Moriette G, Paris-Llado J, Walti Herv\u00e9, Escande Beno\u0131t, Magny Jean-Fran\u00e7ois, Cambonie G, et al. Prospective randomized multicenter comparison of high-frequency oscillatory ventilation and conventional ventilation in preterm infants of less than 30 weeks with respiratory distress syndrome. Pediatrics. 2001;107(2):363\u201372.","journal-title":"Pediatrics"},{"issue":"1","key":"e_1_3_3_36_2","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/s13054-020-2741-x","article-title":"The impact of high frequency oscillatory ventilation on mortality in paediatric acute respiratory distress syndrome","volume":"24","author":"Wong JJ","year":"2020","unstructured":"Wong JJ, Liu S, Dang H, Anantasit N, Phan PH, Phumeetham S, et al). The impact of high frequency oscillatory ventilation on mortality in paediatric acute respiratory distress syndrome. Crit Care. 2020 Jan 31;24(1):31.","journal-title":"Crit Care"},{"issue":"1","key":"e_1_3_3_37_2","doi-asserted-by":"crossref","DOI":"10.1186\/s40560-022-00615-6","article-title":"Ards clinical practice guideline 2021","volume":"10","author":"Tasaka S","year":"2022","unstructured":"Tasaka S, Ohshimo S, Takeuchi M, Yasuda H, Ichikado K, Tsushima K, et al. Ards clinical practice guideline 2021. j intensive care. 2022;10(1).","journal-title":"j intensive care"},{"issue":"4","key":"e_1_3_3_38_2","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1097\/01.PCC.0000227108.38119.2E","article-title":"High-frequency oscillatory ventilation in pediatric patients with acute respiratory failure","volume":"7","author":"Ben Jaballah N","year":"2006","unstructured":"Ben Jaballah N, Khaldi A, Mnif K, Bouziri A, Belhadj S, Hamdi A, et al. High-frequency oscillatory ventilation in pediatric patients with acute respiratory failure. Pediatr Crit Care Med. 2006 Jul;7(4):362\u20137.","journal-title":"Pediatr Crit Care Med"},{"issue":"10","key":"e_1_3_3_39_2","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1097\/00003246-199422100-00006","article-title":"Prospective, randomized comparison of high-frequency oscillatory ventilation and conventional mechanical ventilation in pediatric respiratory failure","volume":"22","author":"Arnold JH","year":"1994","unstructured":"Arnold JH, Hanson JH, Toro-Figuero LO, Gutie\u0155rez J, Berens RJ, Anglin DL. Prospective, randomized comparison of high-frequency oscillatory ventilation and conventional mechanical ventilation in pediatric respiratory failure. Crit Care Med. 1994 Oct;22(10):1530\u20139.","journal-title":"Crit Care Med"},{"issue":"11","key":"e_1_3_3_40_2","doi-asserted-by":"crossref","first-page":"2425","DOI":"10.1097\/00003246-200211000-00004","article-title":"Interactive effects of high-frequency oscillatory ventilation and inhaled nitric oxide in acute hypoxemic respiratory failure in pediatrics","volume":"30","author":"Dobyns EL","year":"2002","unstructured":"Dobyns EL, Anas NG, Fortenberry JD, Deshpande J, Cornfield DN, Tasker RC, et al. Interactive effects of high-frequency oscillatory ventilation and inhaled nitric oxide in acute hypoxemic respiratory failure in pediatrics. Crit Care Med. 2002 Nov;30(11):2425\u20139.","journal-title":"Crit Care Med"},{"issue":"2","key":"e_1_3_3_41_2","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1097\/00003246-199302000-00021","article-title":"High-frequency oscillatory ventilation in pediatric respiratory failure","volume":"21","author":"Arnold JH","year":"1993","unstructured":"Arnold JH, Truog RD, Thompson JE, Fackler JC. High-frequency oscillatory ventilation in pediatric respiratory failure. Crit Care Med. 1993 Feb;21(2):272\u20138.","journal-title":"Crit Care Med"}],"container-title":["Annals of Saudi Medicine"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T12:31:40Z","timestamp":1698841900000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.annsaudimed.net\/doi\/10.5144\/0256-4947.2023.283"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":40,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["10.5144\/0256-4947.2023.283"],"URL":"https:\/\/doi.org\/10.5144\/0256-4947.2023.283","relation":{},"ISSN":["0256-4947","0975-4466"],"issn-type":[{"value":"0256-4947","type":"print"},{"value":"0975-4466","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9]]}}}