{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T01:43:11Z","timestamp":1792028591451,"version":"4.4.0"},"reference-count":37,"publisher":"King Faisal Specialist Hospital and Research Centre","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Saudi Med"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Hypoparathyroidism (HPT) is a significant potential complication following thyroidectomy. Identifying predictors can aid in risk stratification, management, and potentially prevention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBJECTIVE:<\/jats:title>\n                    <jats:p>To determine clinical and biochemical predictors of permanent HPT in post-thyroidectomy patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DESIGN:<\/jats:title>\n                    <jats:p>Single-center, retrospective cohort study<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>SETTINGS:<\/jats:title>\n                    <jats:p>Tertiary care center in Saudi Arabia<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PATIENTS AND METHODS:<\/jats:title>\n                    <jats:p>We conducted a retrospective analysis of 1085 patients who underwent total thyroidectomy from 2015 to 2022. Patients who developed postoperative HPT were categorized into transient and permanent HPT groups. Demographic, surgical, and biochemical variables were analyzed. Multivariable logistic regression was used to identify independent predictors of permanent HPT, using transient HPT as the reference.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>MAIN OUTCOME MEASURES:<\/jats:title>\n                    <jats:p>Identification of independent predictors associated with permanent HPT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>SAMPLE SIZE:<\/jats:title>\n                    <jats:p>1085 patients, 264 with postoperative HPT<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>We had 264 patients (24.3%) who developed postoperative HPT: 207 (19.1%) had transient and 57 (5.2%) had permanent HPT. Independent predictors of permanent HPT included thyroid cancer (Odds ratio, OR 2.08, 95% Confidence Interval, CI 1.03\u20134.17), autoimmune thyroid disease (OR 2.01, 95% CI 1.00\u20134.08), increased thyroid weight (OR 1.52 per 1 SD increase, 95% CI 1.08\u20132.14), and longer hospital stay (\u22657 days) (OR 3.53, 95% CI 1.87\u20136.68). Preoperative vitamin D deficiency was identified as the only modifiable risk factor (OR 2.25, 95% CI 1.17\u20134.32). A postoperative parathyroid hormone (PTH) level \u22641.52 pmol\/L within 24 hours was strongly associated with the risk of permanent HPT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>Permanent HPT is significantly associated with preoperative vitamin D deficiency, thyroid malignancy, autoimmune thyroid disease, and greater thyroid weight. A postoperative PTH level \u22641.52 pmol\/L is a reliable early biochemical predictor. Risk-based stratification may support individualized patient management and follow-up planning.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>LIMITATIONS:<\/jats:title>\n                    <jats:p>This was a single-center, retrospective study, limiting generalizability, in addition to the heterogeneity in surgeon experience and the time of PTH measurements post-operatively.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.5144\/0256-4947.2025.406","type":"journal-article","created":{"date-parts":[[2025,11,23]],"date-time":"2025-11-23T08:09:23Z","timestamp":1763885363000},"page":"406-413","source":"Crossref","is-referenced-by-count":3,"title":["Predictors of permanent hypoparathyroidism following total thyroidectomy: a retrospective analysis"],"prefix":"10.5144","volume":"45","author":[{"given":"Shaza","family":"Samargandy","sequence":"first","affiliation":[{"name":"From the College of Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-5201-2387","authenticated-orcid":true,"given":"Abdulaziz S.","family":"Alotaibi","sequence":"additional","affiliation":[{"name":"From the College of Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulaziz A.","family":"Alzahrani","sequence":"additional","affiliation":[{"name":"From the College of Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suhail A.","family":"Alzahrani","sequence":"additional","affiliation":[{"name":"From the College of Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed H.","family":"Alghamdi","sequence":"additional","affiliation":[{"name":"From the College of Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulrahman M.","family":"Alotaibi","sequence":"additional","affiliation":[{"name":"From the College of Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassan A.","family":"Alsahafi","sequence":"additional","affiliation":[{"name":"From the College of Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayman A.","family":"Alsolami","sequence":"additional","affiliation":[{"name":"From the College of Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hani Z.","family":"Marzouki","sequence":"additional","affiliation":[{"name":"From the Department of Otolaryngology-Head &amp; Neck Surgery, King Abdulaziz University, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saad","family":"Samargandy","sequence":"additional","affiliation":[{"name":"From the Department of Community Medicince, King Abdulaziz University, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3134","reference":[{"key":"e_1_3_2_2_2","unstructured":"Khan AA Bilezikian JP Brandi ML et al. Evaluation and management of hypoparathyroidism: summary statement and guidelines from the Second International Workshop. J Bone Miner Res. 2022."},{"key":"e_1_3_2_3_2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s12020-021-02663-8","article-title":"What are the real rates of temporary hypoparathyroidism following thyroidectomy? It is a matter of definition: a systematic review","volume":"73","author":"Koimtzis GD","year":"2021","unstructured":"Koimtzis GD, Stefanopoulos L, Giannoulis K, Papavramidis TS. What are the real rates of temporary hypoparathyroidism following thyroidectomy? It is a matter of definition: a systematic review. 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Risks and prediction of postoperative hypoparathyroidism due to thyroid surgery. Sci Rep. 2021;11(1):11876.","journal-title":"Sci Rep"},{"issue":"6","key":"e_1_3_2_6_2","doi-asserted-by":"crossref","first-page":"2300","DOI":"10.1210\/jc.2015-3909","article-title":"Presentation of hypoparathyroidism: etiologies and clinical features","volume":"101","author":"Shoback DM","year":"2016","unstructured":"Shoback DM, Bilezikian JP, Costa AG, Dempster D, Dralle H, Khan AA, et al. Presentation of hypoparathyroidism: etiologies and clinical features. 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Arch Otolaryngol Head Neck Surg. 2001;127(3):304\u2013308.","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtumed.2021.08.001"},{"issue":"1","key":"e_1_3_2_9_2","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1186\/s12893-023-02176-3","article-title":"Incidental parathyroidectomy during total thyroidectomy and functional parathyroid preservation: a retrospective cohort study","volume":"23","author":"Melot C","year":"2023","unstructured":"Melot C, Deniziaut G, Menegaux F, Chereau N. Incidental parathyroidectomy during total thyroidectomy and functional parathyroid preservation: a retrospective cohort study. BMC Surg. 2023;23(1):269.","journal-title":"BMC Surg"},{"key":"e_1_3_2_10_2","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.ijsu.2018.05.737","article-title":"Clinicopathological characteristics of incidental parathyroidectomy after total thyroidectomy: the effect on hypocalcemia. 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