{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T11:34:53Z","timestamp":1793878493347,"version":"4.7.0"},"reference-count":22,"publisher":"King Faisal Specialist Hospital and Research Centre","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Saudi Med"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Mesh-based vNOTES lateral suspension is an emerging minimally invasive technique for apical pelvic organ prolapse repair, but the clinical value of fascial fixation of the lateral mesh arms remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBJECTIVES:<\/jats:title>\n                    <jats:p>To compare 12-month anatomical outcomes and recurrence rates between fascial fixation and non-fixation of the lateral mesh arms during mesh-based vNOTES lateral suspension after vaginal hysterectomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DESIGN:<\/jats:title>\n                    <jats:p>Retrospective comparative study<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>SETTINGS:<\/jats:title>\n                    <jats:p>Tertiary referral center<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PATIENTS AND METHODS:<\/jats:title>\n                    <jats:p>We reviewed women who underwent vaginal hysterectomy combined with mesh-based vNOTES lateral suspension for pelvic organ prolapse between March 2022 and March 2026. Patients were grouped according to whether the lateral mesh arms were fixed to the fascia. Preoperative and 12-month postoperative Pelvic Organ Prolapse Quantification (POP-Q) measurements, recurrence, perioperative outcomes, postoperative complications, and mesh erosion were evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>MAIN OUTCOME MEASURES:<\/jats:title>\n                    <jats:p>The primary outcome was recurrence at 12 months, defined as POP-Q point C &gt;\u22121 cm, reflecting clinically significant apical prolapse. Secondary outcomes included POP-Q values and change scores, operative time, estimated blood loss, length of hospital stay, complications, and mesh erosion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>SAMPLE SIZE:<\/jats:title>\n                    <jats:p>101 patients; 46 in the non-fixation group and 55 in the fixation group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      Both groups demonstrated significant improvement in all evaluated POP-Q points at 12 months compared with baseline (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;.001). Recurrence occurred in four patients (8.7%) in the non-fixation group and four patients (7.3%) in the fixation group (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =1.0). Operative time, estimated blood loss, and length of hospital stay were comparable between groups (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =.347,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =.187, and\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =.274, respectively). Similarly, no significant between-group differences were observed in perioperative complications (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =.59), postoperative complications (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =.426), or mesh erosion (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =1.0).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>Fascial fixation of the lateral mesh arms was not associated with improved short-term anatomical, perioperative, or postoperative outcomes at 12 months following mesh-based vNOTES lateral suspension after vaginal hysterectomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>LIMITATIONS:<\/jats:title>\n                    <jats:p>Retrospective design, single-center setting, modest sample size, and 12-month follow-up period.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.5144\/0256-4947.2026.311","type":"journal-article","created":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T04:44:41Z","timestamp":1791089081000},"page":"311-318","source":"Crossref","is-referenced-by-count":0,"title":["Fascial fixation versus non-fixation in vNOTES lateral suspension after vaginal hysterectomy for pelvic organ prolapse"],"prefix":"10.5144","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8516-5493","authenticated-orcid":true,"given":"Havva Bet\u00fcl","family":"Bacak","sequence":"first","affiliation":[{"name":"From the Obstetrics and Gynecology Department, Gaziosmanpa\u015fa Training and Research Hospital, Istanbul, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatma","family":"Ketenci Gencer","sequence":"additional","affiliation":[{"name":"From the Obstetrics and Gynecology Department, Gaziosmanpa\u015fa Training and Research Hospital, Istanbul, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enes Serhat","family":"Co\u015fkun","sequence":"additional","affiliation":[{"name":"From the Department of Obstetrics and Gynecology, Biruni University Tip Fakultesi, Istanbul, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serkan","family":"Kumbasar","sequence":"additional","affiliation":[{"name":"From the Obstetrics and Gynecology Department, Gaziosmanpa\u015fa Training and Research Hospital, Istanbul, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hayat","family":"Terkan","sequence":"additional","affiliation":[{"name":"From the Obstetrics and Gynecology Department, Gaziosmanpa\u015fa Training and Research Hospital, Istanbul, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pelin","family":"P\u0131nar","sequence":"additional","affiliation":[{"name":"From the Obstetrics and Gynecology Department, Gaziosmanpa\u015fa Training and Research Hospital, Istanbul, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayb\u00fcke","family":"Bulut","sequence":"additional","affiliation":[{"name":"From the Department of Obstetrics and Gynecology, Cengiz G\u00f6k\u00e7ek Gynecology and Maternity Hospital, Gaziantep, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Batuhan","family":"Bulut","sequence":"additional","affiliation":[{"name":"From the Department of Obstetrics and Gynecology, TC Sa\u011fl\u0131k Bakanl\u0131\u011f\u0131 Gaziantep City Hospital, Gaziantep, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatih","family":"\u0130rice","sequence":"additional","affiliation":[{"name":"From the Obstetrics and Gynecology Department, Gaziosmanpa\u015fa Training and Research Hospital, Istanbul, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bar\u0131\u015fcan","family":"Aldanmaz","sequence":"additional","affiliation":[{"name":"From the Obstetrics and Gynecology Department, Gaziosmanpa\u015fa Training and Research Hospital, Istanbul, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sinem","family":"Delig\u00f6zo\u011flu","sequence":"additional","affiliation":[{"name":"From the Obstetrics and Gynecology Department, Gaziosmanpa\u015fa Training and Research Hospital, Istanbul, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00fcleyman","family":"Salman","sequence":"additional","affiliation":[{"name":"From the Obstetrics and Gynecology Department, Gaziosmanpa\u015fa Training and Research Hospital, Istanbul, 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