{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T01:04:50Z","timestamp":1792458290563,"version":"4.5.0"},"reference-count":0,"publisher":"AVES YAYINCILIK A.\u015e.","issue":"2","license":[{"start":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T00:00:00Z","timestamp":1751241600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Archives of Rheumatology"],"abstract":"<jats:p>Background\/Aims: Assess circulatory Sirtuin-1 (SIRT1) levels in Behcet's disease (BD) and relationships with disease activity and inflammatory markers.\nMaterials and Methods: Forty BD patients and 40 matched controls. Recorded demographics, disease activity (BDCAF), treatments, organ involvement. Measured CRP, IL-6, TNF-\u03b1, and SIRT1 in fasting blood.\nResults: CRP, IL-6, TNF-\u03b1 higher in BD vs controls, regardless of activity. SIRT1 similar across groups and treatments. Patients with vascular + ocular involvement had lower SIRT1 than ocular only.\nConclusion: Circulatory SIRT1 levels are similar in BD and controls but may associate with vascular involvement.<\/jats:p>","DOI":"10.5152\/archrheumatol.2025.11042","type":"journal-article","created":{"date-parts":[[2025,8,18]],"date-time":"2025-08-18T14:04:31Z","timestamp":1755525871000},"page":"182-188","source":"Crossref","is-referenced-by-count":1,"title":["Examining Sirtuin-1 Levels and Inflammation Markers in Behcet's Disease: A Pilot Study"],"prefix":"10.5152","volume":"40","author":[{"given":"Volkan","family":"Ecesoy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hasan","family":"Ar\u0131c\u0131","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fadime P\u0131nar","family":"Ate\u015f","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Usame \u00d6mer","family":"Osmano\u011flu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hilal","family":"Ecesoy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3111","published-online":{"date-parts":[[2025,6,30]]},"container-title":["Archives of Rheumatology"],"original-title":[],"link":[{"URL":"https:\/\/archivesofrheumatology.org\/index.php\/pub\/article\/download\/1489\/2670","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/archivesofrheumatology.org\/index.php\/pub\/article\/download\/1489\/2671","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/archivesofrheumatology.org\/index.php\/pub\/article\/download\/1489\/2670","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T08:42:42Z","timestamp":1761208962000},"score":1,"resource":{"primary":{"URL":"https:\/\/archivesofrheumatology.org\/index.php\/pub\/article\/view\/1489"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,30]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,6,30]]}},"URL":"https:\/\/doi.org\/10.5152\/archrheumatol.2025.11042","relation":{},"ISSN":["2618-6500"],"issn-type":[{"value":"2618-6500","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,30]]}}}