{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T10:24:21Z","timestamp":1778495061644,"version":"3.51.4"},"reference-count":0,"publisher":"AVES YAYINCILIK A.\u015e.","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["EAJM"],"abstract":"<jats:p>Abstract\n\tFemale adnexial tumors of probable Wolffian origin (FATWO) are rare tumors derived from the remnants of the mesonephric duct. These tumors generally exhibit a low malignant potential, but recurrence and or metastasis is possible during the course of the disease according to the tumors\u2019 possible malignant potential. We report a case of FATWO without estrogen and progesterone receptors and with negative immunostaining for Ki-67 (a proliferation marker) as a probable low-malignant-potential tumor. A 55-year-old woman presented with a complaint of heavy menstrual bleeding and pelvic pain. Preoperative ultrasonographic evaluation revealed an intramural uterine leiomyoma of 4 cm in diameter and a right adnexial solid mass measuring 5 cm in diameter. Following total abdominal hysterectomy and bilateral salpingo-oophorectomy, immunostaining based on the labeled streptavidin-biotin method was performed on sections from representative blocks of paraffin-embedded tissues sampled from the mass, revealing a low mitotic index with negative Ki-67 immunostaining. Immunohistochemical staining with promising new markers and pathological investigation of the entire tumor are needed to determine the malignant behavior of an individual FATWO. Ki-67 is a helpful marker for determining Wolffian duct tumors\u2019 potential malignant behavior.<\/jats:p>","DOI":"10.5152\/eajm.2012.40","type":"journal-article","created":{"date-parts":[[2012,12,14]],"date-time":"2012-12-14T07:41:21Z","timestamp":1355470881000},"page":"172-175","source":"Crossref","is-referenced-by-count":10,"title":["Female Adnexial Tumor of Probable Wolffian Origin (FATWO)  without Ki-67 Expression Reflecting Low Malignant Potential in a 55-Year-Old Woman"],"prefix":"10.5152","volume":"44","author":[{"given":"Serkan","family":"Kahyaoglu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inci","family":"Kahyaoglu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Levent","family":"Sirvan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilker","family":"Sengul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hakan","family":"Timur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leyla","family":"Mollamahmutoglu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3111","published-online":{"date-parts":[[2019,9,3]]},"container-title":["The Eurasian Journal of Medicine"],"original-title":[],"link":[{"URL":"https:\/\/eajm.org\/index.php\/pub\/article\/download\/2483\/2480","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T00:48:28Z","timestamp":1767055708000},"score":1,"resource":{"primary":{"URL":"https:\/\/eajm.org\/index.php\/pub\/article\/view\/2483"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,3]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2012,1,1]]}},"URL":"https:\/\/doi.org\/10.5152\/eajm.2012.40","relation":{},"ISSN":["1308-8742"],"issn-type":[{"value":"1308-8742","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,3]]}}}