{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T05:56:23Z","timestamp":1789192583618,"version":"build-2803163510"},"reference-count":0,"publisher":"AVES YAYINCILIK A.\u015e.","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["EJR"],"abstract":"<jats:p>Childhood sarcoidosis is a chronic multisystemic, non-caseating granulomatous disease of unknown etiology. Early-onset disease classically presents with a triad of skin rash, uveitis, and arthritis, but bone marrow involvement is rare. We report a 9-1\/2- year old Indian female child who presented with bleeding manifestation, skin rash, uveitis, and arthritis. Bone marrow biopsy showed multiple non-necrotizing granulomas comprising epithelioid cells, mature lymphocytes, and multinucleated giant cells with few eosinophils in the background, with negative staining for acid-fast bacilli or fungi. She was treated successfully with oral prednisolone. This is the first report of an early-onset childhood sarcoidosis with bone marrow involvement from India.\n\nCite this article as: Meshram RM, Gajimwar VS, Gholap S, Jhanwar M. Bone marrow involvement: atypical presentation of early-onset childhood sarcoidosis. Eur J Rheumatol 2020; 7(4): 190-4.\n<\/jats:p>","DOI":"10.5152\/eurjrheum.2020.20076","type":"journal-article","created":{"date-parts":[[2020,9,9]],"date-time":"2020-09-09T01:28:42Z","timestamp":1599614922000},"page":"190-194","source":"Crossref","is-referenced-by-count":6,"title":["Bone marrow involvement: Atypical presentation of early-onset childhood sarcoidosis"],"prefix":"10.5152","volume":"7","author":[{"given":"Rajkumar M.","family":"Meshram","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vishal S.","family":"Gajimwar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siddhant","family":"Gholap","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madhuri","family":"Jhanwar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3111","published-online":{"date-parts":[[2020,9,8]]},"container-title":["European Journal of Rheumatology"],"original-title":[],"link":[{"URL":"https:\/\/www.eurjrheumatol.org\/index.php\/pub\/article\/download\/425\/425","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T07:16:14Z","timestamp":1753773374000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.eurjrheumatol.org\/index.php\/pub\/article\/view\/425"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,8]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2020,10,8]]}},"URL":"https:\/\/doi.org\/10.5152\/eurjrheum.2020.20076","relation":{},"ISSN":["2148-4279"],"issn-type":[{"value":"2148-4279","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,8]]}}}