{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T19:08:21Z","timestamp":1754161701484,"version":"3.41.2"},"reference-count":0,"publisher":"AVES YAYINCILIK A.\u015e.","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["EJR"],"abstract":"<jats:p>Biologic disease-modifying agents (bDMARDs) are highly effective in controlling the symptoms of autoimmune rheumatic diseases. The decision on whether to continue bDMARDs following a cancer diagnosis can be challenging for patients and physicians. Here, we describe a case of a middle-aged male with ankylosing spondylitis who was controlled on infliximab (IFX) and found to have a myeloid neoplasm with Platelet-Derived Growth Factor Receptor Beta rearrangement. The patient was started on a tyrosine kinase inhibitor imatinib. Given its significant positive effect on patient\u2019s quality of life, IFX was continued with a favorable outcome. This case highlights the importance of shared decisionmaking in balancing risks and benefits of immunosuppressants in appropriate cases of hematologic malignancy.\n\nCite this article as: Gupta A, Afinogenova Y, Podoltsev NA, Danve A. Concurrent use of tumor necrosis factor inhibitor and tyrosine kinase inhibitor in ankylosing spondylitis and myeloid neoplasm. Eur J Rheumatol. 2022;9(4):215-216.\n<\/jats:p>","DOI":"10.5152\/eurjrheum.2022.21097","type":"journal-article","created":{"date-parts":[[2022,1,24]],"date-time":"2022-01-24T09:11:28Z","timestamp":1643015488000},"page":"215-216","source":"Crossref","is-referenced-by-count":0,"title":["Concurrent use of tumor necrosis factor inhibitor and tyrosine kinase inhibitor in ankylosing spondylitis and myeloid neoplasm"],"prefix":"10.5152","volume":"9","author":[{"given":"Akash","family":"Gupta","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuliya","family":"Afinogenova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikolai A.","family":"Podoltsev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abhijeet","family":"Danve","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3111","published-online":{"date-parts":[[2022,1,24]]},"container-title":["European Journal of Rheumatology"],"original-title":[],"link":[{"URL":"https:\/\/www.eurjrheumatol.org\/index.php\/pub\/article\/download\/544\/544","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T07:10:45Z","timestamp":1753773045000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.eurjrheumatol.org\/index.php\/pub\/article\/view\/544"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,24]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2023,1,16]]}},"URL":"https:\/\/doi.org\/10.5152\/eurjrheum.2022.21097","relation":{},"ISSN":["2148-4279"],"issn-type":[{"type":"electronic","value":"2148-4279"}],"subject":[],"published":{"date-parts":[[2022,1,24]]}}}