{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T11:16:06Z","timestamp":1792062966226,"version":"4.4.0"},"reference-count":0,"publisher":"AVES YAYINCILIK A.\u015e.","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["EJR"],"abstract":"<jats:p>Abstract\n\tObjective: Neutrophil lymphocyte ratio (NLR) has emerged as a valuable and reliable method for follow-up of systemic inflammatory disease. We herein aimed to evaluate the role of NLR in the clinical follow-up of inflammation and also to compare its relationship with other measures, such as erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI). \n\n\t\u00a0\n\n\tMaterial and Methods: A total of 35 active ankylosing spondylitis (AS) and 38 healthy volunteers were included in the study. The patient group was enrolled for treatment with one anti-tumor necrosis factor (TNF) drug. Total blood count, ESR, CRP, and BASDAI score were obtained before and 3 months following the treatment. NLR was found with a mathematical calculation of the ratio of neutrophils with lymphocytes.\n\n\t\u00a0\n\n\tResults: The mean NLR value of the control group and patients was 1.90\u00b10.89 and 2.67\u00b11.17, respectively (p&lt;0.05). After a 3-month course of treatment, the patient group had a mean NLR value of 1.8\u00b10.7, which was significantly lower than pretreatment values (p&lt;0.001). The post-treatment mean ESR, CRP, and BASDAI scores were significantly lower than mean baseline scores (p&lt;0.001, p=0.007, p&lt;0.001, respectively). Also, NLR was found to be correlated with BASDAI, ESR, and CRP (r=0.388, p&lt;0.001; r=0.455, p&lt;0.0001; and r=0.3389, p&lt;0.005, respectively).\n\n\t\u00a0\n\n\tConclusion: Neutrophil lymphocyte ratio could be a reliable and easily accessible method for follow-up of patients with AS.\n\n\t\n\n\t\u00a0<\/jats:p>","DOI":"10.5152\/eurjrheumatol.2014.034","type":"journal-article","created":{"date-parts":[[2014,9,9]],"date-time":"2014-09-09T03:45:05Z","timestamp":1410234305000},"page":"101-105","source":"Crossref","is-referenced-by-count":33,"title":["Neutrophil lymphocyte ratio can be a valuable marker in defining disease activity in patients who have started anti-tumor necrosis factor (TNF) drugs for ankylosing spondylitis"],"prefix":"10.5152","volume":"1","author":[{"given":"Belk\u0131s Nihan","family":"Co\u015fkun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa Ferhat","family":"\u00d6ks\u00fcz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selime","family":"Ermurat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ay\u015fe Nur","family":"Tufan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nurdan","family":"Oru\u00e7o\u011flu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akif","family":"Do\u011fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ediz","family":"Dalk\u0131l\u0131\u00e7","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yavuz","family":"Pehlivan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3111","published-online":{"date-parts":[[2019,9,3]]},"container-title":["European Journal of Rheumatology"],"original-title":[],"link":[{"URL":"https:\/\/www.eurjrheumatol.org\/index.php\/pub\/article\/download\/28\/28","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T07:30:24Z","timestamp":1753774224000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.eurjrheumatol.org\/index.php\/pub\/article\/view\/28"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,3]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2019,9,3]]}},"URL":"https:\/\/doi.org\/10.5152\/eurjrheumatol.2014.034","relation":{},"ISSN":["2148-4279"],"issn-type":[{"value":"2148-4279","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,3]]}}}