{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T02:50:18Z","timestamp":1769136618394,"version":"3.49.0"},"reference-count":0,"publisher":"Caleo","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Adv Otol."],"abstract":"<jats:p>Von Hippel\u2013Lindau disease (VHL) is a rare autosomal dominant disorder. It is caused by a mutation in the tumor suppressor gene localized at\u00a03p25-26. Endolymphatic sac tumors (ELSTs) are rare low-grade adenocarcinomas which can occur sporadically but are more commonly found\u00a0in association with VHL disease. In this paper, we present 3 siblings who underwent comprehensive vestibular assessment following a genetic\u00a0diagnosis of VHL, and review the literature on audiovestibular findings in VHL\/ELST in children. This is the first time that newer objective vestibular\u00a0function tests like the video head impulse test (vHIT), the suppression head impulse test (SHIMP), and the cervical vestibular evoked myogenic\u00a0potential test (cVEMP) have been performed in children with VHL to yield meaningful information about vestibular function. Monitoring audiological\u00a0function has been suggested for early detection of ELSTs. It remains to be seen whether monitoring of vestibular function in patients with\u00a0VHL from an earlier age may yield valuable information about progression of the disease.\n\nCite this article as: Fatih Turgut N, Crunkhorn R, Iqbal J, Dasgupta S. Vestibular function in children with Von Hippel\u2013Lindau disease. J Int Adv Otol.\u00a02021; 17(4): 361-367.<\/jats:p>","DOI":"10.5152\/iao.2021.0190","type":"journal-article","created":{"date-parts":[[2021,7,16]],"date-time":"2021-07-16T09:18:34Z","timestamp":1626427114000},"page":"361-367","source":"Crossref","is-referenced-by-count":1,"title":["Vestibular Function in Children With Von Hippel\u2013Lindau Disease"],"prefix":"10.65717","volume":"17","author":[{"given":"Nesrettin Fatih","family":"Turgut","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosa","family":"Crunkhorn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javed","family":"Iqbal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soumit","family":"Dasgupta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"55248","published-online":{"date-parts":[[2021,7,1]]},"container-title":["The Journal of International Advanced Otology"],"original-title":[],"link":[{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/download\/1516\/1514","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/download\/1525\/1522","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/download\/1525\/1522","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T10:42:50Z","timestamp":1769078570000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/view\/1525"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,1]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,7,16]]}},"URL":"https:\/\/doi.org\/10.5152\/iao.2021.0190","relation":{},"ISSN":["2148-3817"],"issn-type":[{"value":"2148-3817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,1]]}}}