{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T04:40:24Z","timestamp":1769402424959,"version":"3.49.0"},"reference-count":0,"publisher":"Caleo","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Adv Otol."],"abstract":"<jats:p>Lemierre\u2019s syndrome is characterized by internal jugular vein thrombosis and systemic septic embolism; it is a fatal complication of upper respiratory\u00a0tract infections. To date, it has not been demonstrated how the upper respiratory tract inflammation spreads from the primary infection\u00a0site to internal jugular vein and systemic thrombosis. We report a very rare case of Lemierre\u2019s syndrome derived from malignant otitis externa in\u00a0which the spread of infection and thrombosis process were identified by imaging. A 61-year-old man with severe diabetes mellitus visited our\u00a0hospital with consciousness disturbance and right posterior neck pain. He complained of right ear pain and otorrhea several days prior to the\u00a0neck pain. Contrast-enhanced computed tomography demonstrated thrombosis in internal jugular vein and multiple lung abscesses. Temporal\u00a0bone images revealed continuous lesions from skull base osteomyelitis to suboccipital abscess and sigmoid sinus thrombosis. We diagnosed the\u00a0patient as having Lemierre\u2019s syndrome secondary to skull base osteomyelitis following malignant otitis externa. The patient clinically recovered\u00a0with a combination of drainage of suboccipital abscess and long-term administration of antibiotics, which is the standard treatment of malignant\u00a0otitis externa. Considering the details of imaging and bacterial examination is very useful for understanding the pathophysiology and determining\u00a0appropriate treatment in Lemierre\u2019s syndrome pathophysiology and determining appropriate treatment in Lemierre\u2019s syndrome.\n\nCite this article as: Ogi M, Takahashi K, Morita Y, Horii A. Lemierre\u2019s syndrome due to malignant otitis externa: imaging studies revealed its\u00a0systemic dissemination. J Int Adv Otol. 2021; 17(5): 461-464.<\/jats:p>","DOI":"10.5152\/iao.2021.20142","type":"journal-article","created":{"date-parts":[[2021,10,5]],"date-time":"2021-10-05T02:35:34Z","timestamp":1633401334000},"page":"461-464","source":"Crossref","is-referenced-by-count":3,"title":["Lemierre\u2019s Syndrome Due to Malignant Otitis Externa: Imaging Studies Revealed Its Systemic Dissemination"],"prefix":"10.65717","volume":"17","author":[{"given":"Manabu","family":"Ogi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kuniyuki","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuka","family":"Morita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arata","family":"Horii","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"55248","published-online":{"date-parts":[[2021,9,1]]},"container-title":["The Journal of International Advanced Otology"],"original-title":[],"link":[{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/download\/1567\/1565","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/download\/1543\/1540","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/download\/1543\/1540","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T10:41:25Z","timestamp":1769078485000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/view\/1543"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,1]]},"references-count":0,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2021,9,30]]}},"URL":"https:\/\/doi.org\/10.5152\/iao.2021.20142","relation":{},"ISSN":["2148-3817"],"issn-type":[{"value":"2148-3817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,1]]}}}