{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T10:37:26Z","timestamp":1788431846764,"version":"build-2803163510"},"reference-count":0,"publisher":"Caleo","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Adv Otol."],"abstract":"<jats:p>BACKGROUND AND OBJECTIVES: Vestibular schwannomas (VS) frequently lead to ipsilateral sensorineural hearing loss (HL) as part of its natural\u00a0history or as a result of treatment. Cochlear implantation represents a well-documented treatment of profound HL that cannot be treated\u00a0adequately with a conventional hearing aid, thus being offered to selected VS patients. A functional cochlea and cochlear nerve are prerequisites\u00a0for sound perception with a cochlear implant (CI). The potential impact of radiotherapy on these structures is thus an important issue for subsequent\u00a0CI hearing outcomes. The objective of this article is to present a case and to review the existing literature on the outcomes of cochlear\u00a0implantation in irradiated VS patients systematically.\n\nMETHODS: A systematic literature review using preferred reporting items for systematic reviews and meta-analyses was conducted. Medline was\u00a0searched systematically. Papers reporting ipsilateral CI outcomes after radiotherapy of VS were included. Additionally, results of CI after stereotactic\u00a0radiotherapy in a 54-year-old male with neurofibromatosis type 2 are presented.\n\nRESULTS: A total of 14 papers (33 patients) fulfilled inclusion criteria. Moderate preoperative HL was found in 11 patients. Six had moderate to\u00a0severe HL, whereas 16 had severe HL or total deafness. Postoperative hearing outcomes varied from poor in 27% of patients to excellent in 19%,\u00a0with remaining cases lying in between (mean follow-up of 19 months). Most patients achieved improvement in hearing and quality of life.\n\nCONCLUSION: Despite variation in the degree of hearing outcome, CI after radiotherapy of VS appears to be effective in the majority of cases,\u00a0as more than 70% of patients have good or excellent outcomes within 1-2 years post-implantation. Subjective benefits are considerable, even in\u00a0cases with relatively poor objective outcome.\n\nCite this article as: Tian L, West N, Cay\u00e9-Thomasen P. Cochlear implantation after radiotherapy of vestibular schwannomas. J Int Adv Otol. 2021;\u00a017(5): 452-460.<\/jats:p>","DOI":"10.5152\/iao.2021.21008","type":"journal-article","created":{"date-parts":[[2021,10,5]],"date-time":"2021-10-05T02:35:34Z","timestamp":1633401334000},"page":"452-460","source":"Crossref","is-referenced-by-count":15,"title":["Cochlear Implantation After Radiotherapy of Vestibular Schwannomas"],"prefix":"10.65717","volume":"17","author":[{"given":"Luchen","family":"Tian","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niels","family":"West","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per","family":"Cay\u00e9-Thomasen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"55248","published-online":{"date-parts":[[2021,9,1]]},"container-title":["The Journal of International Advanced Otology"],"original-title":[],"link":[{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/download\/1566\/1564","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/download\/1544\/1541","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/download\/1544\/1541","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T10:41:24Z","timestamp":1769078484000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/view\/1544"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,1]]},"references-count":0,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2021,9,30]]}},"URL":"https:\/\/doi.org\/10.5152\/iao.2021.21008","relation":{},"ISSN":["2148-3817"],"issn-type":[{"value":"2148-3817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,1]]}}}