{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T19:41:15Z","timestamp":1790106075298,"version":"4.0.1"},"reference-count":0,"publisher":"Caleo","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Adv Otol."],"abstract":"<jats:p>OBJECTIVES: Cytomegalovirus (CMV) infection is the most common intrauterine viral infection, affecting approximately 0.5-2.5% of all live births\u00a0in the world. The majority of patients are asymptomatic at birth, but several clinical consequences are related to this infection, including neurosensory\u00a0hearing loss. The cochlear implant is the treatment of choice when the hearing loss is severe to profound. Compare the audiological\u00a0evolution after cochlear implant surgery in a group of children born with congenital CMV infection compared to a control group of children born\u00a0with a genetic cause of congenital hearing loss. Determine prognostic factors predicting the outcome of patients with congenital hearing loss\u00a0secondary to CMV infection following cochlear implantation.\n\nMETHODS: Our retrospective study aimed at the analysis of 48 patients with cochlear implants, 25 patients with congenital CMV, and 23 patients\u00a0in the control group with cochlear cause of hearing loss, who were matched for gender, age of onset, and type of hearing loss. Primary outcomes\u00a0are auditory evolution with the Infant-Toddler Meaningful Auditory Integration Scale (IT-MAIS) and the multimedia audiologic test (MAT).\u00a0Secondary outcomes are evaluation of prognostic factors for the CMV group, like MRI severity sign, antiviral treatment, and neuropsychological\u00a0disorder.\n\nRESULTS: For the MAT, the results are 73.9% in the CMV group and 81.6% in the control group (P = .03). For the IT-MAIS, the results are 29.3\/40 in\u00a0the CMV group and 29.2\/40 in the control group (P = .96). In the CMV group, the children treated with antiviral treatment have IT-MAIS difference\u00a0of 28.5\/40 compared to 23.2\/40 for the children without antiviral treatment (P = .03). We found a little trend in the correlation between auditory\u00a0results and the presence of\u00a0 neuropsychological disorders, but there are no statistically significant results.\n\nCONCLUSION: The results of the audiological tests in the CMV group allow an adequate functioning, even if lower than in the control group.\nThere are benefits of implantation in patients with CMV, and\u00a0 audiological results are still satisfactory for proper functioning. CMV patients enjoy\u00a0superior results in terms of hearing, with antiviral treatment.\n\nCite this article as: H. Bolduc S, Bussi\u00e8res R, Philippon D, C\u00f4t\u00e9 M. The correlation of congenital CMV infection and the outcome of cochlear\u00a0implantation. J Int Adv Otol. 2021;17(3):190-194.<\/jats:p>","DOI":"10.5152\/iao.2021.9335","type":"journal-article","created":{"date-parts":[[2021,6,4]],"date-time":"2021-06-04T08:23:40Z","timestamp":1622795020000},"page":"190-194","source":"Crossref","is-referenced-by-count":10,"title":["The Correlation of Congenital CMV Infection and the Outcome of Cochlear Implantation"],"prefix":"10.65717","volume":"17","author":[{"given":"Simon-Pierre","family":"H. Bolduc","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Bussi\u00e8res","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Philippon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathieu","family":"C\u00f4t\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"55248","published-online":{"date-parts":[[2021,5,1]]},"container-title":["The Journal of International Advanced Otology"],"original-title":[],"link":[{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/download\/1485\/1483","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/download\/1512\/1509","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/download\/1512\/1509","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T10:42:58Z","timestamp":1769078578000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/view\/1512"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,1]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021,5,31]]}},"URL":"https:\/\/doi.org\/10.5152\/iao.2021.9335","relation":{},"ISSN":["2148-3817"],"issn-type":[{"value":"2148-3817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,1]]}}}