{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T08:12:56Z","timestamp":1788941576369,"version":"build-2803163510"},"reference-count":0,"publisher":"Caleo","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Adv Otol."],"abstract":"<jats:p>BACKGROUND: Assessment of nystagmus fixation suppression can be used as an additional diagnostic tool for patients with an acute vestibular syndrome to distinguish between a central or peripheral cause. We investigated the ability of physicians to detect fixation suppression using a nystagmus simulation model.\n\nMETHODS: We used a nystagmus simulator to measure the accuracy of the nystagmus fixation suppression test. Fixation suppression was assessed randomly in 6170 trials by 20 otorhinolaryngologists and neurologists, segregated into 2 groups based on their neurootological experience, a beginner and an experienced group. The simulator presented random nystagmus slow velocity (SPV) reductions and presented 3 conditions with either changed nystagmus frequency, amplitude, or both.\n\nRESULTS: The cutoff for the discernment of fixation suppression ranged from 1.2 to 14\u00b0\/s nystagmus velocity difference. The more intense the baseline nystagmus was, the more difficult was the detection of fixation suppression. There was not significant difference (P &gt; .05) in the cutoff values in the experts group compared to the novices for all 3 different conditions. Both, novices and experts, detected frequency changes easier than differences of the nystagmus amplitude. Test sensitivity was very low (19%-65%) for discernment of small nystagmus velocity differences of \u22642\u00b0\/s by experts.\n\nCONCLUSION: In our study, there was no difference between experts and novices in detection of nystagmus suppression by visual fixation. The examiners could only detect large suppression effects at low-intensity baseline nystagmus. Overall, the sensitivity and accuracy of a clinical fixation suppression test is low and the assistance with a video-oculography device is highly recommended.\n\nCite this article as: Siegrist S, Wyss T, Korda A, Mantokoudis G. Clinical assessment of the nystagmus fixation suppression test: An experimental study. J Int Adv Otol. 2024;20(3):241-246.<\/jats:p>","DOI":"10.5152\/iao.2024.231249","type":"journal-article","created":{"date-parts":[[2024,8,26]],"date-time":"2024-08-26T08:24:40Z","timestamp":1724660680000},"page":"241-246","source":"Crossref","is-referenced-by-count":3,"title":["Clinical Assessment of the Nystagmus Fixation Suppression Test: An Experimental Study"],"prefix":"10.65717","volume":"20","author":[{"given":"Stefanie","family":"Siegrist","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Wyss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Athanasia","family":"Korda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgios","family":"Mantokoudis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"55248","published-online":{"date-parts":[[2024,5,23]]},"container-title":["The Journal of International Advanced Otology"],"original-title":[],"link":[{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/download\/1820\/1818","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/advancedotology.org\/index.php\/pub\/article\/download\/1802\/1799","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/advancedotology.org\/index.php\/pub\/article\/download\/1802\/1799","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T11:55:22Z","timestamp":1769082922000},"score":1,"resource":{"primary":{"URL":"https:\/\/advancedotology.org\/index.php\/pub\/article\/view\/1802"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,23]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2024,5,23]]}},"URL":"https:\/\/doi.org\/10.5152\/iao.2024.231249","relation":{},"ISSN":["2148-3817"],"issn-type":[{"value":"2148-3817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,23]]}}}