{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T09:52:31Z","timestamp":1789638751506,"version":"4.0.0"},"reference-count":0,"publisher":"Caleo","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Adv Otol."],"abstract":"<jats:p>Background:\u00a0Over the last decade, delayed gadolinium-enhanced magnetic resonance imaging (MRI) of the inner ear has become increasingly used as an objective marker for the diagnosis of endolymphatic hydrops (EH) in M\u00e9ni\u00e8re\u2019s disease (MD). This study evaluates the utility of this imaging technique in the first 100 patients scanned at our tertiary center.\r\n\r\nMethods:\u00a0A retrospective study was conducted in the Department of Otology and Neuro-otology at University College London Hospitals between October 2020 and May 2022. Patients were classified into 4 groups: \u201cdefinite MD,\u201d \u201cprobable MD,\u201d isolated cochlear symptoms, and MD-vestibular migraine (VM) overlap syndrome. The local imaging protocol consisted of an intravenous gadolinium (IV-Gd) injection followed by T2 SPACE and 3D-real inversion recovery magnetic resonance imaging (MRI) of the inner ears after 4 hours.\r\n\r\nResults:\u00a0The first 100 patients scanned were included. All patients with \u201cdefinite MD\u201d and MD-VM overlap syndrome had evidence of radiological EH on MRI. About 38% of patients in the \u201cprobable MD\u201d group and 25% of patients in the isolated cochlear hydrops group had radiological EH. For the \u201cdefinite MD\u201d group, 98% of positive scans correlated with disease laterality; this was 87% in the \u201cprobable MD\u201d group. Duration of disease &gt;4 years and more severe hearing loss were found to be statistically significant factors for the detection of EH.\r\n\r\nConclusion:\u00a0Our study demonstrates that EH is much more likely to be detected in patients with a clinical diagnosis of \u201cdefinite MD\u201d or MD-VM overlap syndrome, and also correlates with the increasing duration and severity of symptoms. Further studies using standardized imaging protocols would be helpful in comparing outcomes.<\/jats:p>","DOI":"10.5152\/iao.2025.241584","type":"journal-article","created":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T01:58:12Z","timestamp":1738288692000},"page":"1-6","source":"Crossref","is-referenced-by-count":2,"title":["The Utility of Contrast-Enhanced 3D-Real Inversion Recovery Magnetic Resonance Imaging in the Diagnosis of Endolymphatic Hydrops\u2014A Retrospective Study of a Newly Implemented Clinical Service at a Tertiary Center"],"prefix":"10.65717","volume":"21","author":[{"family":"Jawad Abdulla","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Yasmin Abbas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Sofia Otero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Simon Morley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Simon Morley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Susan Jawad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Charlotte Agrup","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Hala Kanona","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"55248","published-online":{"date-parts":[[2025,1,27]]},"container-title":["The Journal of International Advanced Otology"],"original-title":[],"link":[{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/download\/1874\/1872","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/download\/1891\/1879","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/download\/1891\/1879","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T09:51:04Z","timestamp":1769075464000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/view\/1891"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,27]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,1,27]]}},"URL":"https:\/\/doi.org\/10.5152\/iao.2025.241584","relation":{},"ISSN":["2148-3817"],"issn-type":[{"value":"2148-3817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,27]]}}}