{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T15:02:15Z","timestamp":1780498935593,"version":"3.54.1"},"reference-count":0,"publisher":"Caleo","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Adv Otol"],"abstract":"<jats:p>BACKGROUND:\u00a0This study examines low-dose botulinum toxin at acupuncture points for its effects on vestibular symptoms, headaches, depression, anxiety, and stress in vestibular migraine patients.\r\n\u00a0\r\nMETHODS:\u00a0This prospective study included patients with vestibular migraine per Barany Society criteria. Fifty units of Onabotulinum toxin were injected using a 31-gauge needle at 5 units\/0.1 mL, diluted from 100 units with 2 mL of 0.9% sodium chloride. The injections were given at predetermined acupuncture points: Yintang (EX-HN3), Taiyang (EX-HN5), Baihui (GV20), Shuaigu (GB8), Fengchi (GB20), and Tianzhu (BL10). Six-month follow-up assessments included assessments using the Migraine Disability Assessment Scale (MIDAS), Dizziness Handicap Inventory-Screening Form (DHI-S), Vertigo Symptom Scale-Short Form (VSS-SF), Depression Anxiety Stress Scale (DASS-21), and Allodynia Symptom Checklist (ASC-12).\r\n\u00a0\r\nRESULTS:\u00a0Statistically significant improvements were observed in MIDAS, VSS-SF, DHI-S, and DASS-21 scores at both 3 and 6 months (P &lt; .05).\r\n\u00a0\r\nCONCLUSION:\u00a0Application of Onabotulinum toxin A (BoNT-A) to acupuncture points alleviated headache, vestibular symptoms, and anxiety, with benefits persisting for up to 6 months.<\/jats:p>","DOI":"10.5152\/iao.2025.251876","type":"journal-article","created":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T07:52:06Z","timestamp":1753170726000},"page":"1-6","source":"Crossref","is-referenced-by-count":1,"title":["Efficacy of Low-Dose BoNT-A Acupoint Injections in Managing Headache, Vertigo, and Allodynia in Vestibular Migraine"],"prefix":"10.65717","volume":"21","author":[{"family":"G\u00f6k\u00e7e Aydemir","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Faz\u0131l Necdet Ard\u0131\u00e7","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"C\u00fcneyt Orhan Kara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Eylem De\u011firmenci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"55248","published-online":{"date-parts":[[2025,7,21]]},"container-title":["The Journal of International Advanced Otology"],"original-title":[],"link":[{"URL":"https:\/\/advancedotology.org\/index.php\/pub\/article\/download\/1916\/1907","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/advancedotology.org\/index.php\/pub\/article\/download\/1916\/1907","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T14:05:30Z","timestamp":1780495530000},"score":1,"resource":{"primary":{"URL":"https:\/\/advancedotology.org\/index.php\/pub\/article\/view\/1916"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,21]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,7,18]]}},"URL":"https:\/\/doi.org\/10.5152\/iao.2025.251876","relation":{},"ISSN":["2148-3817"],"issn-type":[{"value":"2148-3817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,21]]}}}