{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T01:48:06Z","timestamp":1769132886321,"version":"3.49.0"},"reference-count":0,"publisher":"Caleo","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Adv Otol."],"abstract":"<jats:p>BACKGROUND:\u00a0This study assessed the audio-vestibular function and symptoms in patients diagnosed with Lyme neuroborreliosis (LNB).METHODS:\u00a0Patients with LNB were included prospectively. Diagnosis was based on a cerebrospinal fluid leukocyte count \u2267 10 \u00d7 106cells\/L anda positive blood antibody production or intrathecal Borrelia burgdorferi antibody titer together with symptoms of LNB. Vestibular assessmentsincluded video head impulse test and a caloric test. Hearing was assessed by pure-tone audiometry at discharge and 30 days after hospitalization and compared to a healthy age- and sex-matched control dataset. Symptoms were assessed by a structured interview and the DizzinessHandicap Inventory (DHI).RESULTS:\u00a0Nineteen patients were included in the study. Four (21%) patients had vestibular dysfunction; 2 were unilateral and 2 were bilateral.The lateral semicircular canal was dysfunctional in 3 patients, the anterior semicircular canal in 2 patients, and the posterior semicircular canal in1 patient. Sensorineural hearing loss, defined by audiometry, was present in 9 (47%) patients according to the audiometry at discharge and 10(59%) patients during the follow-up audiometry. Hearing did not differ significantly from the age- and sex-matched control dataset. Vestibulardysfunction was not significantly associated with the total DHI score or with the mean PTA (Pure tone audiometry). The most commonly reportedsymptoms were peripheral nerve palsy (47%), dizziness (32%), fatigue (32%) and headache (32%).CONCLUSION:\u00a0Audio-vestibular function was affected in patients with LNB but correlated poorly with the patients\u2019 self-reported audio-vestibular symptoms.<\/jats:p>","DOI":"10.5152\/iao.2025.251982","type":"journal-article","created":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T12:01:46Z","timestamp":1758628906000},"page":"1-8","source":"Crossref","is-referenced-by-count":0,"title":["Audio-Vestibular Function in Patients Diagnosed with Lyme Neuroborreliosis"],"prefix":"10.65717","volume":"21","author":[{"family":"Elisa Skovgaard Jensen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Jonas Bruun Kj\u00e6rsgaard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Per Cay\u00e9-Thomasen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Dan Dupont Hougaard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Nicolas Lyneborg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Christian Thomas Brandt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Malene Kirchmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"55248","published-online":{"date-parts":[[2025,9,22]]},"container-title":["The Journal of International Advanced Otology"],"original-title":[],"link":[{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/download\/1929\/1920","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/download\/1929\/1920","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T09:43:56Z","timestamp":1769075036000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/view\/1929"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,22]]},"references-count":0,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2025,9,4]]}},"URL":"https:\/\/doi.org\/10.5152\/iao.2025.251982","relation":{},"ISSN":["2148-3817"],"issn-type":[{"value":"2148-3817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,22]]}}}