{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T11:27:55Z","timestamp":1779362875190,"version":"3.51.4"},"reference-count":0,"publisher":"AVES YAYINCILIK A.\u015e.","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Turkish Journal of Gastroenterology"],"abstract":"<jats:p>Abstract Background\/Aims: To elucidate the role of 18F-fluorodeoxyglucose positron emission tomography\/computed tomography (18F-FDG-PET\/CT) imaging as an independent prognostic factor in hepatocellular carcinoma (HCC). Materials and Methods: A total of 104 patients with newly diagnosed HCC who underwent 18F-FDG-PET\/CT imaging from 2009 to 2014 were reviewed retrospectively. The ratio of the maximal tumor standardized uptake value (SUV) to the mean mediastinum SUV (TSUVmax\/MSUVmean) was evaluated as the predictive factor. Results: A high TSUVmax\/MSUVmean ratio (&amp;ge;3.1) was significantly associated with tumor burden indices, including &amp;alpha;-fetoprotein (p&amp;lt;0.001), amino transaminase (AST) (p=0.007), tumor size (p=0.043), Tumor, Node, and Metastasis (TNM) stage (p&amp;lt;0.001), and Barcelona Clinic Liver Cancer (BCLC) staging (p&amp;lt;0.001). The mortality rate was higher (48.1% vs. 23.1%, p&amp;lt;0.001) in patients with a high TSUVmax\/MSUVmean ratio (&amp;ge;3.1). Among the 47 patients who underwent transarterial chemoembolization (TACE), patients with a high TSUVmax\/MSUVmean ratio (&amp;ge;3.1) were more likely to have recurrence following TACE (18\/19 vs. 18\/28, p=0.016). Conclusion: A high TSUVmax\/MSUVmean ratio on 18F-FDG-PET\/CT imaging can serve as an independent prognostic factor in HCC and may predict tumor recurrence after TACE.<\/jats:p>","DOI":"10.5152\/tjg.2015.0152","type":"journal-article","created":{"date-parts":[[2015,6,4]],"date-time":"2015-06-04T08:58:19Z","timestamp":1433408299000},"page":"344-350","source":"Crossref","is-referenced-by-count":16,"title":["18F-FDG PET CT as a prognostic factor in hepatocellular carcinoma"],"prefix":"10.5152","volume":"26","author":[{"given":"Eunae","family":"Cho","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chung-Hwan","family":"Jun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ban-Seok","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong-Jun","family":"Son","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Won-Suk","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung-Kyu","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3111","published-online":{"date-parts":[[2015,7,15]]},"container-title":["Turkish Journal of Gastroenterology"],"original-title":[],"link":[{"URL":"https:\/\/www.turkjgastroenterol.org\/index.php\/tjg\/article\/download\/2781\/2462","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:48:17Z","timestamp":1777376897000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.turkjgastroenterol.org\/index.php\/tjg\/article\/view\/2781"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7,15]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2015,7,15]]}},"URL":"https:\/\/doi.org\/10.5152\/tjg.2015.0152","relation":{},"ISSN":["2148-5607"],"issn-type":[{"value":"2148-5607","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,7,15]]}}}