{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T20:06:49Z","timestamp":1791662809184,"version":"4.3.4"},"reference-count":0,"publisher":"AVES YAYINCILIK A.\u015e.","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Turkish Journal of Gastroenterology"],"abstract":"<jats:p>Background: Bovine lactoferrin addition to regimens of Helicobacter pylori treatment has been tried, with conflicting results.\n\nAim: To assess the effect of bovine lactoferrin in addition to the anti-H. pylori treatment.\n\nMethods: We enrolled 400 H. pylori-infected patients who were randomized into 4 equal groups: (A): proton-pump-based triple therapy\n\n(PpTT) for 2 weeks, (B): sequential therapy for 2 weeks, (C): proton-pump-based triple therapy plus bovine lactoferrin for 2 weeks, and\n\n(D): sequential therapy plus bovine lactoferrin for 2 weeks.\n\nResults: In the per-protocol analysis, the success in groups A, B, C, and D were 70.3%, 82.8%, 85.6%, and 94.5%, respectively (P &lt; .001).\n\nThe treatment success rate for the sequential therapy plus bovine lactoferrin regimen was significantly higher than that with sequential\n\ntherapy alone (94.5% vs. 82.8%, P = .013). The same applied for proton-pump-based triple therapy (85.6% vs. 70.3%, P = .014). The\n\naddition of bovine lactoferrin and the presence of endoscopic corpus gastritis were independent predictors for successful eradication\n\nof H. pylori.\n\nConclusion: Bovine lactoferrin could hasten the effectiveness of the proton-pump-based triple therapy or sequential therapy for H.\n\npylori eradication.<\/jats:p>","DOI":"10.5152\/tjg.2021.20923","type":"journal-article","created":{"date-parts":[[2021,9,22]],"date-time":"2021-09-22T03:58:01Z","timestamp":1632283081000},"page":"742-749","source":"Crossref","is-referenced-by-count":15,"title":["Efficacy of Lactoferrin with Standard Triple Therapy or Sequential Therapy for Helicobacter pylori Eradication: A Randomized Controlled Trial"],"prefix":"10.5152","volume":"32","author":[{"given":"Fahmy H.","family":"Hablass","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sameh A.","family":"Lashen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eman A.","family":"Alsayed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3111","published-online":{"date-parts":[[2021,9,15]]},"container-title":["Turkish Journal of Gastroenterology"],"original-title":[],"link":[{"URL":"https:\/\/www.turkjgastroenterol.org\/index.php\/tjg\/article\/download\/3772\/3435","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T11:24:46Z","timestamp":1773228286000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.turkjgastroenterol.org\/index.php\/tjg\/article\/view\/3772"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,15]]},"references-count":0,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2021,9,15]]}},"URL":"https:\/\/doi.org\/10.5152\/tjg.2021.20923","relation":{},"ISSN":["2148-5607"],"issn-type":[{"value":"2148-5607","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,15]]}}}