{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T15:44:43Z","timestamp":1767800683256,"version":"3.49.0"},"reference-count":0,"publisher":"AVES YAYINCILIK A.\u015e.","license":[{"start":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T00:00:00Z","timestamp":1767571200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Turkish Journal of Gastroenterology"],"abstract":"<jats:p>Background\/Aims: Helicobacter pylori infection remains an important global health issue, particularly among older adults for whom related complications are more frequent. However, epidemiological data on the elderly populations in T\u00fcrkiye are limited. This study aimed to determine the prevalence, associated factors, and endoscopic\u2013histopathological correlations of H. pylori infection in a large geriatric cohort.\r\nMaterials and Methods: This single-center retrospective study included 2000 adults aged \u226565 years who underwent esophagogastro duodenoscopy between January 2023 and December 2024. Active infection was determined by stool antigen testing according to the Updated Sydney System. Demographic, clinical, endoscopic, and histopathological parameters were analyzed, and independent predic tors were identified using multivariate logistic regression.\r\nResults: The mean age of the participants was 77.5 \u00b1 7.8 years, and 50.2% were male. The overall prevalence of H. pylori infections was 56.3%. Prior eradication therapy was independently protective (31.3% vs. 66.1%; P &lt; .001). Infection rates did not differ significantly according to sex, smoking, alcohol use, or comorbidities. The highest positivity rates were observed for atrophic gastritis (60.8%), pan gastritis (58.0%), and antral gastritis (56.2%). The prevalence declined modestly in the oldest-old group (\u226585 years), whereas atrophic and metaplastic changes increased with age.\r\nConclusion: Helicobacter pylori infection remains highly prevalent among elderly individuals in T\u00fcrkiye, showing a gradual decline com pared with historical national data but a persistent association with premalignant mucosal changes. Early detection and individualized eradication strategies are essential to optimize geriatric gastrointestinal care.\r\n\u00a0\r\nCite this article as: \u00d6zden Y, Bulur O. Prevalence of Helicobacter pylori infection in geriatric adults: a single-center cohort study from T\u00fcrkiye. Turk J Gastroenterol. Published online January 5, 2026. doi: 10.5152\/tjg.2025.25499.<\/jats:p>","DOI":"10.5152\/tjg.2025.25499","type":"journal-article","created":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T12:55:52Z","timestamp":1767790552000},"source":"Crossref","is-referenced-by-count":0,"title":["Prevalence of Helicobacter pylori Infection in Geriatric  Adults: A Single-Center Cohort Study from T\u00fcrkiye"],"prefix":"10.5152","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5760-3529","authenticated-orcid":false,"given":"Yavuz","family":"\u00d6zden","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0332-3871","authenticated-orcid":false,"given":"Oktay","family":"Bulur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3111","published-online":{"date-parts":[[2026,1,5]]},"container-title":["Turkish Journal of Gastroenterology"],"original-title":[],"link":[{"URL":"https:\/\/www.turkjgastroenterol.org\/index.php\/tjg\/article\/download\/4402\/4076","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.turkjgastroenterol.org\/index.php\/tjg\/article\/download\/4402\/4076","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T12:55:53Z","timestamp":1767790553000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.turkjgastroenterol.org\/index.php\/tjg\/article\/view\/4402"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,5]]},"references-count":0,"URL":"https:\/\/doi.org\/10.5152\/tjg.2025.25499","relation":{},"ISSN":["2148-5607"],"issn-type":[{"value":"2148-5607","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,5]]}}}