{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,9,23]],"date-time":"2022-09-23T12:30:30Z","timestamp":1663936230009},"reference-count":24,"publisher":"Universa BV","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["AGEB"],"published-print":{"date-parts":[[2021,2,16]]},"abstract":"<jats:p>Background and study aims : To investigate the safety and efficacy of splenectomy for hepatolenticular degeneration (HLD) patients with PLT less than 20 \u00d7 109\/L.\n\nPatients and methods : A total of 244 HLD patients with hyper-splenism underwent splenectomy. According to the preopera-tive PLT values, the patients were divided into three groups : group A of 53 patients with PLT &lt; 20 \u00d7 109\/L ; group B of 92 patients with 20 \u00d7 109\/L \u2264 PLT \u2264 30 \u00d7 109\/L ; group C of 99 patients with PLT &gt; 30 \u00d7 109\/L. General information including : blood cell counts, liver function , coagulation function 1 day before sugery and 1, 7, 14 days after surgery ; intraoperative blood loss ; operation time ; vital signs at the beginning, at 60 minutes and the end of the operation. Pressure and blood oxygen ; postoperative drainage ; postoperative complications and mortality.\n\nResults : Blood cell counts, liver function, and coagulation func-tion were improved after splenectomy in three groups (P&lt;0.05) ; there was no significant difference in blood loss, operation time, vital signs during the operation, postoperative drainage, postoper-ative complications and mortality between three groups (P&gt;0.05).\n\nConclusion : For HLD patients with hypersplenism, it is safe and effective to conduct splenectomy under PLT &lt; 20 \u00d7 109\/L.<\/jats:p>","DOI":"10.51821\/84.1.943","type":"journal-article","created":{"date-parts":[[2021,5,13]],"date-time":"2021-05-13T00:46:39Z","timestamp":1620866799000},"page":"51-56","source":"Crossref","is-referenced-by-count":1,"title":["Platelet safety range before splenectomy for hypersplenism : based on 244 cases of splenectomy in hepatolenticular degeneration patients"],"prefix":"10.51821","volume":"84","author":[{"given":"S.T.","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Feng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.H.","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Q.S.","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"27062","published-online":{"date-parts":[[2021,2,16]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"KATHAWALA  M,  GM  HIRSCHFIELD.  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