{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T21:24:02Z","timestamp":1788643442513,"version":"build-2803163510"},"reference-count":13,"publisher":"Universa BV","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["AGEB"],"published-print":{"date-parts":[[2021,6]]},"abstract":"Giant condyloma acuminatum, also known as Buschke-L\u00f6wenstein tumor, is a rare variant of verrucous carcinoma presenting in the ano-genital region. While its metastatic potential is limited, aggressive local growth is common, with invasion and destruction of the surrounding tissues often causing important therapeutic challenges. Also, data to inform the optimal management approach are scarce and mostly limited to anectodical reports. We present the case of a human immunodeficiency virus-associated locally advanced Buschke L\u00f6wenstein tumor that was successfully treated with extensive surgery.<\/jats:p>","DOI":"10.51821\/84.2.343","type":"journal-article","created":{"date-parts":[[2021,7,30]],"date-time":"2021-07-30T00:01:50Z","timestamp":1627603310000},"page":"343-345","source":"Crossref","is-referenced-by-count":8,"title":["Buschke-L\u00f6wenstein tumor in a human immunodeficiency virus-positive patient : a case report and short literature review"],"prefix":"10.51821","volume":"84","author":[{"given":"V","family":"Ledouble","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Sclafani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Hendlisz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Gomez Galdon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Liberale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27062","published-online":{"date-parts":[[2021,6]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"BUSCHKE A., L\u00d6WENSTEIN L. \u00dcber carcinomahnliche condylomata acuminata des penis. Klinische Wochenschrift 1925, 4 : 1726-8.","DOI":"10.1007\/bf01728480"},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"AHSAINI M., TAHIRI Y., TAZI M.F., ELAMMARI J., MELLAS S., KHALLOUK A. et al. Verrucous carcinoma arising in an extended giant condyloma acuminatum (Buschke-L\u00f6wenstein tumor) : a case report and review of the literature. Journal of Medical Case Reports. 2013, 7 : 273.","DOI":"10.1186\/1752-1947-7-273"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"KIM H.G., KESEY J.E., GRISWOLD J.A. Giant anorectal condyloma acuminatum of Buschke-L\u00f6wenstein presents difficult management decisions. Journal of Surgical Case Reports. 2018, 4 :1-4.","DOI":"10.1093\/jscr\/rjy058"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"GARLAND S.M., STEBEN M., SINGS H.L., JAMES M., LU S., RAILKAR R et al. Natural history of genital warts : analysis of the placebo arm of 2 randomized phase III trials of a quadrivalent human papillomavirus (types 6, 11, 16, and 18) vaccine. J. Infect. Dis. 2009, 199 : 805-814.","DOI":"10.1086\/597071"},{"key":"ref4","unstructured":"SPINU D., RADULESCU A., BRATU O., CHECHERITA I.A., RANETTI A.E., MISCHIANU D. Giant condyloma acuminatum-Buschke lowenstein disease- a literature review. Chirurgia 2014, 109 : 445-450."},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"BEN KRIDIS W., WERDA I., CHARFI S., TOUMI N., BOUDAWARA T., MZALI R. et al. Buschke-L\u00f6wenstein anal tumor : an ambiguous entity. Exp. Oncol. 2019 41, 2 : 182-184.","DOI":"10.32471\/exp-oncology.2312-8852.vol-41-no-2.13119"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"SHENOY S., NITTALA M., ASSAF Y. Anal carcinoma in giant anal condyloma, multidisciplinary approach necessary for optimal outcome : two case reports ans review of literature. World J. Gastrointest. Oncol. 2019 February 15, 11(2) : 172-180.","DOI":"10.4251\/wjgo.v11.i2.172"},{"key":"ref7","doi-asserted-by":"publisher","unstructured":"GALGANO M.T., CASTLE P.E., ATKINS K.A., BRIX W.K., NASSAU S.R., STOLER M.H. Using biomarkers as objective standards in the diagnosis of cervical biopsies. Am. J. Surg. Pathol. 2010 Aug, 34(8) : 1077-1087.","DOI":"10.1097\/pas.0b013e3181e8b2c4"},{"key":"ref8","doi-asserted-by":"publisher","unstructured":"CHU Q. D., VEZERIDIS M. P., LIBBEY N. P., WANEBO H.J. Giant condyloma acuminatum (Buschke-L\u00f6wenstein tumor) of the anorectal and perianal regions. Analysis of 42 cases. Diseases of the colon & Rectum. 1994, 37, no. 9, 950-957.","DOI":"10.1007\/bf02052606"},{"key":"ref9","doi-asserted-by":"publisher","unstructured":"PURZYCKA-BOHDAN D., SZCZERKOWSKA-DOBOSZ A., SWIATECKA-CZAJ J., PEKSA R., URBAN M., SZCZYPIOR M. et al. Buschke-L\u00f6wenstein tumour associated with low-risk human papillomavirus genotypes succesfully treated surgically. Adv. Dermatol. Allergol. 2019, XXXVI (1) : 112-114.","DOI":"10.5114\/ada.2019.82831"},{"key":"ref10","unstructured":"TRIPOLI M., CORDOVA A., MAGGI F., MOSCHELLA F. Giant condylomata (Buschke-L\u00f6wenstein tumours) : our case load in surgical treatment and review of the current therapies. Eur. Rev. Med. Pharmacol. Sci. 2012, 16 : 747-751."},{"key":"ref11","doi-asserted-by":"publisher","unstructured":"SANDHU R., MIN Z., BHANOT N. A gigantic anogenital lesion : Buschke-L\u00f6wenstein tumor. Case Rep. Dermatol. Med. 2014, 2014 : 650714.","DOI":"10.1155\/2014\/650714"},{"key":"ref12","doi-asserted-by":"publisher","unstructured":"GEUSAU A., HEINZ-PEER G., VOLC-PLATZER B., STINGL G., KIRNBAUER R. Regression of deeply infiltrating Giant Condyloma (Buschke-L\u00f6wenstein tumor) following long-term intralesional interferon alfa therapy. Arch. Dermatol. 2000 June, 136(6) : 707-710","DOI":"10.1001\/archderm.136.6.707"}],"container-title":["Acta Gastro Enterologica Belgica"],"original-title":[],"language":"en","deposited":{"date-parts":[[2021,7,30]],"date-time":"2021-07-30T12:46:04Z","timestamp":1627649164000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ageb.be\/ageb-journal\/ageb-volume\/ageb-article\/1910\/Buschke-L%C3%B6wenstein%20tumor%20in%20a%20human%20immunodeficiency%20virus-positive%20patient%20:a%20case%20report%20and%20short%20literature%20review\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":13,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021,6]]},"published-print":{"date-parts":[[2021,6]]}},"URL":"https:\/\/doi.org\/10.51821\/84.2.343","relation":{},"ISSN":["1784-3227"],"issn-type":[{"value":"1784-3227","type":"print"}],"subject":[],"published":{"date-parts":[[2021,6]]}}}