{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T16:55:13Z","timestamp":1700758513654},"reference-count":9,"publisher":"Universa BV","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["AGEB"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:p>Pemphigus vulgaris (PV) is a rare autoimmune blistering disorder of the skin and mucous membranes. The true prevalence of esophageal involvement is unknown; esophageal symptoms almost always occur in the context of oral mucosa involvement. We report the case of a 66-year-old man with cutaneous blisters and esophageal symptoms that did not respond to acid suppression therapy. Esophagogastroduodenoscopy showed esophageal ulcers and mucosal desquamation. Biopsies were consistent with the diagnosis of PV. The patient was started on immunosuppressive therapy, achieving remission. This represents a rare case of esophageal involvement of PV without mucosal involvement and draws attention to a rare cause of dysphagia, which can be fatal if left untreated<\/jats:p>","DOI":"10.51821\/84.2.365","type":"journal-article","created":{"date-parts":[[2021,7,30]],"date-time":"2021-07-30T00:01:55Z","timestamp":1627603315000},"page":"365-366","source":"Crossref","is-referenced-by-count":2,"title":["Pemphigus vulgaris presenting as esophageal ulceration. Report of an underdiagnosed manifestation"],"prefix":"10.51821","volume":"84","author":[{"given":"C","family":"Leal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Barbeiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Vasconcelos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"27062","published-online":{"date-parts":[[2021,6]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"KNEISEL A., HERTL, M. Autoimmune bullous skin diseases. Part 1: clinical manifestations.  Journal  der  Deutschen  Dermatologischen  Gesellschaft 2011, 844-857.","DOI":"10.1111\/j.1610-0387.2011.07793.x"},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"ROBINSON JC., LOZADA-NUR F., FRIEDEN I. Oral pemphigus vulgaris: a review of the literature and a report on the management of 12 cases. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 1997, 84(4) : 349-55.","DOI":"10.1016\/s1079-2104(97)90030-5"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"CALKA O., AKDENIZ N., TUNCER I., METIN A., CESUR RS. Oesophageal involvement during attacks in pemphigus vulgaris patients. Clin. Exp. Dermatol. 2006 Jul, 31(4) : 515-9.","DOI":"10.1111\/j.1365-2230.2006.02132.x"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"GATT K. et  al.  Superimposed  esophageal  pemphigus  vulgaris  and  herpes  simplex infection. Annals of gastroenterology 2019, 654-654.","DOI":"10.20524\/aog.2019.0408"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"FAIAS S., LAGE P., SACHSE F. et  al.  Pemphigus  vulgaris  with  exclusive  involvement  of  the  esophagus:  case  report  and  review.  Gastrointest.  Endosc. 2004, 60 : 312-15.","DOI":"10.1016\/s0016-5107(04)01605-0"},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"W\u00dcRTTENBERGER A, BARNERT J, WIENBECK M. Long-lasting odynophagia and haematemesis \u2013 the only clinical signs of a pemphigus vulgaris. Z. Gastroenterol. 2002, 40 : 419-24.","DOI":"10.1055\/s-2002-32124"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"SALEM  Z.,  STRIPPOLI  A.,  DEPASQUALE  JR.  Isolated  esophageal pemphigus vulgaris. Am J Gastroenterol 2003;98:201.","DOI":"10.1111\/j.1572-0241.2003.08344.x"},{"key":"ref7","doi-asserted-by":"publisher","unstructured":"AL-JANABI A,  GREENFIELD  S.  Pemphigus  vulgaris  :  a  rare  cause  of dysphagia. Case Reports 2015, 2015 : bcr2015212661.","DOI":"10.1136\/bcr-2015-212661"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"AHMED AR, MOY R. Death in pemphigus. J. Am. Acad. Dermatol. 1982, 7 : 221-8","DOI":"10.1016\/S0190-9622(82)70111-2"}],"container-title":["Acta Gastro Enterologica Belgica"],"original-title":[],"language":"en","deposited":{"date-parts":[[2021,7,30]],"date-time":"2021-07-30T12:46:16Z","timestamp":1627649176000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ageb.be\/ageb-journal\/ageb-volume\/ageb-article\/1914\/Pemphigus%20vulgaris%20presenting%20as%20esophageal%20ulceration.%20Report%20of%20an%20underdiagnosedmanifestation\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":9,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021,6]]},"published-print":{"date-parts":[[2021,6]]}},"URL":"https:\/\/doi.org\/10.51821\/84.2.365","relation":{},"ISSN":["1784-3227"],"issn-type":[{"value":"1784-3227","type":"print"}],"subject":[],"published":{"date-parts":[[2021,6]]}}}